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Nadolol 80mg
Apo-Nadolol general information
What is Apo-Nadolol used for?
Apo-Nadolol tablets 80mg are used to treat a variety of conditions of the cardiovascular system. These include, control of mild to moderate hypertension (high blood pressure), alone as monotherapy or in combination with other antihypertensive agents, especially thiazide diuretics, to lower blood pressure and reduce the risk of complications such as stroke and heart attack. Apo-Nadolol tablets 80mg are also used for long-term management of angina (chest pain) in patients with heart disease; and control of most forms of arrhythmias (rapid or irregular heart beat). There is also some evidence that using Apo-Nadolol tablets 80mg long-term may help in the prevention of myocardial infarction (heart attack) and treatment of heart failure to improve survival and quality of life. Apo-Nadolol tablets 80mg are also used for preventing migraine, and to treat symptoms of hyperthyroidism (overactive thyroid) as well as preparing patients for thyroid surgery. Apo-Nadolol tablets 80mg work through a common mechanism in several different body systems to manage the condition and relieve symptoms by reducing heart rate (pulse), workload on the heart (force needed to pump) and oxygen demand by the heart, which increases blood flow and lowers blood pressure.
How does Apo-Nadolol work?
Apo-Nadolol tablets 80mg contain nadolol, a non-selective beta-blocker (also known as beta adrenergic antagonist), that binds to beta receptors found in vascular smooth muscle of blood vessel walls and several organs of the body, including the heart and lungs. Nadolol in Apo-Nadolol tablets 80mg blocks the action of chemicals called catecholamines, such as adrenaline (epinephrine) and noradrenaline (nor epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works binds to beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are reduced or inhibited by nadolol in Apo-Nadolol tablets 80mg, to slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. When the heart beats more slowly and with less force, this reduces the pain associated with angina and frequency of angina attacks, also helps the heart beat to become more regular and reduces the force needed to pump blood around the body, which helps lower blood pressure. Since beta-receptors are found in many tissues, all short-term and long-term symptom relief due to taking Apo-Nadolol tablets 80mg, is based on blocking beta-receptors in the target tissue, for example, reducing symptoms associated with hyperthyroidism (overactive thyroid), including rapid heart rate, sweating and tremor. Although the mechanism by which Apo-Nadolol tablets 80mg help prevent migraine is not fully known, it is thought to involve prevention of vasoconstriction (blood vessel narrowing) of the internal carotid artery, by blocking beta receptors in the brain and prevention of excessive adrenergic vasodilation in the external carotid artery, which happens during a migraine attack. Apo-Nadolol tablets 80mg are formulated for controlled release so that nadolol is that released in a sustained and time controlled manner, to ensure a more even effect over 24 hours, which provides better symptom relief with fewer side effects.
What does Apo-Nadolol contain?
Apo-Nadolol tablets 80mg contain the active ingredient nadolol, a beta-blocker that is used to treat variety of conditions of the cardiovascular system and other conditions.
Treating high blood pressure (hypertension) with Apo-Nadolol
Apo-Nadolol tablets 80mg contain nadolol, a non-selective beta-blocker (also known as beta adrenergic antagonist), that binds to beta receptors that are found in vascular smooth muscle in blood vessel walls and several organs of the body, including the heart lungs and kidney. Nadolol in Apo-Nadolol tablets 80mg blocks the action of chemicals called catecholamines, such as adrenaline (epinephrine) and noradrenaline (nor epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline binds to beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are reduced or inhibited by nadolol in Apo-Nadolol tablets 80mg, to slow heart rate and dilate (widen) blood vessels, which prevents resistance to blood flow in peripheral blood vessels and increases blood flow and oxygen to the heart, which result in lower blood pressure. Lowering blood pressure using Nadolol tablets 80mg reduces the risk of complications such as stroke and heart attack, due to high blood pressure.
Treating heart disease with Apo-Nadolol
Apo-Nadolol tablets 80mg contain nadolol, a non-selective beta-blocker (also known as beta adrenergic antagonist), that that binds to beta receptors that are found in vascular smooth muscle in blood vessel walls and several organs of the body, including the heart lungs and kidney. Nadolol in Apo-Nadolol tablets 80mg and blocks the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress, with effects that slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. Apo-Nadolol tablets 80mg are used to treat a variety of conditions of the cardiovascular system to improve survival, reduce symptoms and improve the quality of life in patients with heart disease, including, control of hypertension (high blood pressure), management of angina (chest pain); long-term prevention of myocardial infarction (heart attack) and treatment of heart failure.
What are the side effects of Apo-Nadolol?
The most commonly reported side effects when taking Apo-Nadolol tablets 80mg include: bradycardia (slow heart beat), heart failure (shortness of breath on exertion), dizziness, gastrointestinal disturbances (diarrhoea, constipation, nausea, vomiting, abdominal pain), fatigue, sleepiness, bronchospasm, cold hands and feet (narrowing of the airways), headache.
When should Apo-Nadolol not be used?
You should not use Apo-Nadolol tablets 80mg if you:
- are allergic to nadolol or any ingredients in Apo-Nadolol
- are pregnant or are breastfeeding, without discussion with your doctor
- have a history of obstructive lung disorder, bronchial asthma or bronchospasm
- are diabetic and taking hypoglycaemic therapy, without discussion with your doctor as metoprolol may prolong the hypoglycaemic response to insulin
- have poor peripheral blood circulation, uncontrolled heart failure, low blood pressure (hypotension)
- have a phaeochromocytoma (a rare tumour of the adrenal gland) which is not already being treated with other medicines
- have certain other heart problems
- are taking medication that may interact with Apo-Nadolol, including: other medicines for high blood pressure; angina or an irregular heart beat such as calcium channel blockers (diltiazem, verapamil, and nifedipine), antiarrhythmics (disopyramide) digoxin, clonidine, hydralazine; other beta-blockers, including eye drops; the antibiotic rifampicin; adrenaline for emergencies like anaphylaxis; monoamine oxidase inhibitors; antiinflammatories like ibuprofen or indomethacin; cimetidine for reflux and ulcers; chlorpromazine for psychiatric disorders.
How should Apo-Nadolol be taken?
You should take your Apo-Nadolol tablets 80mg with a glass of water, once daily, with or without food. The dose of Apo-Nadolol tablets 80mg that you are taking depends on what you are being treated for and may be gradually increased by your doctor, depending on your condition and your response. You must take your tablets every day, as instructed and if you are advised to stop taking them, withdrawal should be gradual and treatment should not be discontinued abruptly.
How long should you take Apo-Nadolol?
You should take your Apo-Nadolol tablets 80mg for as long as your doctor recommendations, which may be for a few days, weeks, months or longer depending on the condition you are being treated for.
Missed dose of Apo-Nadolol
If you miss a dose of Apo-Nadolol tablets 80mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Apo-Nadolol be stored?
You should store your Apo-Nadolol below 30°C in a cool dry place, protected from light and moisture..
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Anti Anxiety
Anxiolytic medicationLike all antidepressant drugs, anxiolytic medications act directly at the level of the brain to restore the chemical imbalance that causes symptoms of extreme anxiety.
- Buspirone works by interacting with receptors for the mood enhancing chemical messengers in the brain or neurotransmitters, particularly serotonin and noradrenaline, also dopamine and acetylcholine. Buspirone does not act on receptor sites in the brain that are targets for various sedation-causing drugs like benzodiazepines, barbiturates and inhaled anaesthetics. Therefore buspirone exerts its antianxiety effects without sedation, muscle relaxation, and without compromising mental alertness.
- Tradazone increases the amounts of serotonin and noradrenaline by inhibiting reuptake as well as increasing their activity in the brain. However, it also has sedative properties, by acting on the histamine receptor, which is why it is helpful for treating anxiety.
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Neoceuticals
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Men's Health
About androgens
Androgens are steroid sex hormones produced mainly in the testes that control the development of the male sex organs, the testes, penis, seminal vesicles and prostate gland. They also regulate and maintain secondary male characteristics like the development of body and facial hair, increase in bone and muscle mass and deepening of the voice at puberty. Females also produce small amounts of androgens in the ovaries, but in some cases over production causes androgenisation with characteristics like unwanted body hair.
The main androgens are the male hormone testosterone and its active metabolite dihydrotestosterone (DHT), which is much more potent than testosterone. Both testosterone and DHT bind to the androgen receptor within responsive cells, including brain, bone, hair follicles, testes and prostate cells.
Increased production of or sensitivity to testosterone is thought to be involved in conditions like hypersexuality and aggression in male sex offenders. Also increased sensitivity to DHT and increased conversion of testosterone to DHT is thought to contribute to the hair loss process in male pattern baldness.
The prostate gland
The prostate gland is a small organ that lies just below the bladder and surrounds the top of the urethra, which is the tube that carries urine from the bladder. The prostate gland contributes to the seminal fluid made mainly by the seminal vesicles and the small amount made by the testes, which also contains sperm. Seminal fluid is transported by the urethra through the penis during ejaculation.
Growth and development of the prostate gland is controlled by testosterone, which binds to androgen receptors inside prostate cells. Conditions of the prostate gland include:
- Prostatitis, which is inflammation of the prostate usually due to an infection.
- Benign Prostatic Hyperplasia (BPH), which is an enlarged prostate but is not cancerous.
- Prostate cancer, which is an androgen-dependent tumour and needs testosterone for the cancer cells to grow.
Erectile dysfunction
Erectile dysfunction (ED) is also known as impotence in men and is the inability to achieve or maintain a hard erect penis suitable for sexual activity, which is normally the natural response to sexual stimulation. ED is due to decreased blood flow into the penis and can be treated by specific medication taken at the time of planned sexual activity.
Treatments for men’s health problems
Medications available for treating specific men’s health problems include:
- Anti-androgens that block the production of testosterone and its effects on cells containing androgen receptors, and are used to treat prostate cancer; also hypersexuality in male sex offenders.
- Inhibitors of the enzyme 5α-reductase that converts testosterone to DHT, and is used to treat BPH and male pattern baldness.
- Alpha blockers or alpha-adrenergic antagonists that relax muscle cells in the prostate gland and are used to treat symptoms of BPH.
- Inhibitors of the enzyme phosphodiesterase type 5 (PDE5) that widen blood vessels allowing blood flow into penis, and are used to treat ED.
- Prostaglandins that relax smooth muscle and are used to treat ED.
- Dietary supplements containing a naturally occurring 5α-reductase inhibitor, used to support prostate health and to treat BPH and male pattern baldness.
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Urimax 0.2mg
Urimax general information
What is Urimax used for?
Urimax capsules 0.2mg are used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. Urimax capsules 0.2mg relieve the symptoms of urinary retention caused by restricted urine flow as the prostate becomes enlarged and presses against the urethra (urine outlet tube from the bladder), which helps urine to flow more easily, prevents urine backlog in the bladder and restores bladder control. This relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine. The improved urine flow and reduction in symptoms may reduce the need for surgery.
How does Urimax work?
Urimax capsules 0.2mg contain tamsulosin, an alpha1-blocker (also known as alpha-adrenergic antagonist), that binds selectively to the alpha adrenergic receptor in smooth muscle of the prostate gland and blocks the action of naturally occurring adrenergic chemicals like noradrenaline which causes smooth muscle cells to contract and tighten. Benign prostatic hyperplasia (BPH) is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells. Tamsulosin in Urimax capsules 0.2mg relaxes these muscle cells which relieves the pressure exerted by the enlarged prostate gland on the urethra (urine outlet tube from the bladder); and also causes muscle cells in the neck of the bladder to relax. The action of Tamsulosin in Urimax capsules 0.2mg removes the blockage to urine flow caused by the prostate gland and allows urine to flow more freely through the urethra; it also relaxes the bladder neck, allowing urine to pass out of the bladder more easily. Urimax capsules 0.2mg are formulated for modified release, which means that the rate of absorption of the active ingredient tamsulosin into your blood is controlled and you need only take one capsule a day.
What does Urimax contain?
Urimax capsules 0.2mg contain the active ingredient tamsulosin, an alpha1-blocker used to treat urinary symptoms in benign prostatic hyperplasia (BPH).
Treating urinary symptoms of benign prostatic hyperplasia (BPH) with Urimax
Urimax capsules 0.2mg contain tamsulosin, which is used to treat functional symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate gland. BPH is due to overgrowth of the smooth muscle cells within the prostate gland and increased muscle tone of these cells, which causes the prostate glad to compress the urethra (urine outlet tube from the bladder) running through the gland and obstructs urine flow. Tamsulosin in Urimax capsules 0.2mg is an alpha1-blocker (also known as alpha-adrenergic antagonist), that binds selectively to the alpha adrenergic receptor in smooth muscle of the prostate gland and blocks the action of naturally occurring adrenergic chemicals like noradrenaline, which causes smooth muscle cells to contract and tighten. Urimax capsules 0.2mg relaxes the smooth muscle cells in the prostate gland and removes the pressure against the urethra, allowing urine to flow more freely through the urethra; and also relaxes the bladder neck, allowing urine to pass out of the bladder more easily. This action relieves symptoms like need for frequent urination, inability to empty the bladder, strain and difficulty passing urine. The improved urine flow and reduction in symptoms may reduce the need for surgery.
What are the side effects of Urimax?
The most commonly reported side effects when taking Urimax capsules 0.2mg include: dizziness, headache, abnormal ejaculation, asthenia (weakness), postural hypotension (dizziness on standing) and palpitations. A less common side effect is a persistent painful erection which should be reported to your doctor.
When should Urimax not be used?
You should not use Urimax capsules 0.2mg if you:
- are allergic to tamsulosin or any ingredients in Urimax capsules 0.2mg
- have liver or kidney disease
- have a history of orthostatic hypotension (dizziness, weakness)
- are taking medications that interact with Urimax, including: other alpha-blockers that relaxes smooth muscle, the antiinflammatory diclofenac, the anticoagulant warfarin, cimetidine for stomach ulcers
How should Urimax be taken?
You should take your Urimax capsules 0.2mg swallowed whole with a glass of water, once daily 30 minutes after your first meal of the day. You should continue to take your Urimax capsules 0.2mg for 2-4 weeks; if your symptoms have not improved, your doctor may increase you dose.
How long should you take Urimax?
You should continue to take your Urimax capsules 0.2mg continually for 2-4 weeks, if you miss a few days you may need to begin your course of treatment again.
Missed dose of Urimax
If you miss a dose of Urimax capsules 0.2mg, take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Urimax be stored?
You should Store your Urimax capsules 0.2mg in a cool dry place at room temperature below 30°C, and keep out of direct sunlight.
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