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Arrow Topiramate-50 60 Tablets/Pack


Arrow Topiramate-50 60 Tablets/Pack

Topiramate-50mg

 

Product Name
Arrow Topiramate-50 60 Tablets/Pack
Active Ingredient
Topiramate 50mg
Manufacturer
Arrow Pharmaceuticals
Product Type
Anticonvulsant, Anti-epileptic
Product expiry date we are currently shipping
Discontinued, no stock

This product has been discontinued, but we do have alternatives below.

Arrow-Topiramate tablets 50mg contain topiramate, an anticonvulsant used to treat epilepsy and control seizures, also to prevent migraine attacks. 

Arrow-Topiramate general information

What is Arrow-Topiramate used for?

Arrow-Topiramate tablets 50mg are used to treat epilepsy in adults and children (over 2 years) to control seizures.  Arrow-Topiramate tablets 50mg are used as monotherapy (on its own) for adults and children who have just been diagnosed with idiopathic epilepsy (of unknown cause) and who have either generalised tonic-clonic seizures, seizures affecting the whole brain (formerly known as grand mal seizures), which usually last 1-3 minutes; or partial seizures, which affect only part of the brain but can spread to the whole brain and these are called secondarily generalised seizures.  Arrow-Topiramate tablets 50mg are also used in addition to another medication for controlling seizures in adults and children (over 2 years of age) in partial onset seizures, generalised tonic-clonic seizures but who have been unable to achieve control of seizures with other medications; also in children for treatment seizures associated with of Lennox-Gastaut syndrome, a form of childhood-onset epilepsy that causes frequent seizures and developmental problems.  Arrow-Topiramate tablets 50mg are also used for the prevention of migraines in adults who have regular migraines (3 or more per month). 

How does Arrow-Topiramate work?

Arrow-Topiramate tablets 50mg contain topiramate, an anticonvulsant used to treat epilepsy and control seizures.  Nerve cells throughout the central nervous system communicate by sending out electrical signals, generated by the movement of electrically charged particles in and out of nerve cells, which travel to the all parts of the body via chemical messengers called neurotransmitters.  This usually happens in an orderly fashion to control all our actions and thought processes.  Epileptic seizures are thought to be caused by abnormal electrical activity in the brain, with uncontrolled, rapid and repetitive electrical signals being sent continually to various parts of the body, although the trigger for this abnormality is not known.  Topiramate in Arrow-Topiramate tablets 50mg works directly on the brain cells to reduce the rate at which electrical signals are generated, calming the overactive nerve activity, by three different mechanisms.  Conduction of electrical impulses is dependent on the flow of positive sodium ions into and out of the nerve cell through special sodium channels.  Topiramate blocks these sodium channels and therefore, reduces the neurone’s ability to send out continuous signals which cause seizures.  Topiramate also has the ability to enhance the activity of gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter that regulates how much neurones can be excited (stimulated to send out electrical impulses), and inhibits the activity of the excitatory neurotransmitter glutamate, which adds to the calming effect on brain electrical activity.  These three mechanisms are thought to contribute to the anticonvulsant activity of Arrow-Topiramate tablets 50mg, which control seizures in epilepsy, but cannot cure them.

What does Arrow-Topiramate contain?

Arrow-Topiramate tablets 50mg contain the active ingredient topiramate, which is an anticonvulsant used to treat epilepsy and control seizures.  They also contain microcrystalline cellulose, sodium starch glycollate, pregelatinised maize starch, lactose, aniseed flavour and saccharin sodium and colouring agent Opadry AMB 80W62680 Yellow.

Treating epilepsy with Arrow-Topiramate

Arrow-Topiramate tablets 50mg contain topiramate, an anticonvulsant used to treat epilepsy in adults and children (over 2 years) to control tonic-clonic seizures, which are seizures affecting the whole brain (formerly known as grand mal seizures), and partial seizures, which affect only part of the brain but can spread to the whole brain and are called secondarily generalised seizures.  Epileptic seizures happen when there is abnormal electrical activity in the brain, with uncontrolled, rapid and repetitive electrical signals being sent continually to various parts of the body, although the trigger for this abnormality is not known.  Topiramate in Arrow-Topiramate tablets 50mg works directly on the brain to reduce the rate at which electrical signals are generated, by blocking the ability of nerve cells to transmit electrical signals.  This action is thought to contribute to the anticonvulsant activity of Arrow-Topiramate tablets 50mg, which prevent the overload of electrical activity in the brain that causes seizures in epilepsy and therefore controls the seizures, but cannot cure epilepsy.

Arrow-Topiramate for preventing migraine

Arrow-Topiramate tablets 50mg contain topiramate, an anticonvulsant that is used to treat epilepsy to control seizures.  They are also used for the prevention of migraines in adults who have regular migraines (3 or more per month) that interfere with normal daily activities.  Topiramate in Arrow-Topiramate tablets 50mg works directly on the brain to reduce the rate at which electrical signals are generated and reducing the transmission of electrical signals by over excitable nerve cells.  This action of Arrow-Topiramate tablets 50mg is thought to contribute to the blocking of pain signals, which reduces the occurrence of a migraine headache.  Arrow-Topiramate tablets 50mg are not intended to treat a migraine attack but can control the number of migraine attacks if they happen regularly and frequently, to help you manage your daily life.

What are the side effects of Arrow-Topiramate?

The most commonly reported side effects when taking Arrow-Topiramate tablets 50mg include: unusual tiredness, drowsiness, weakness, dizziness; decrease in appetite or weight loss, slowness of thought processes (bradyphrenia), tingling and numbness of hands and feet (paresthesia); headache; nausea, diarrhoea, constipation; memory impairment; double vision (diplopia); inability to sleep; speech disturbances; anxiety and depression;

When should Arrow-Topiramate not be used?

You should not use Arrow-Topiramate tablets 50mg if you:

  • are allergic to topiramate or any ingredients in Arrow-Topiramate
  • are pregnant or are breastfeeding
  • have or have had kidney stones
  • have kidney disease or liver disease or glaucoma
  • have a psychiatric disorder
  • are taking medication that interact with Arrow-Topiramate, including: other epilepsy medicines like phenytoin or carbamazepine; digoxin for heart failure; CNS depressant medicines and alcohol; oral contraceptives; lithium and risperidone (for bipolar disorder and schizophrenia), the diuretic hydrochlorothiazide; metformin, pioglitazone, glibenclamide for diabetes; the anticonvulsant valproic acid
  • are taking any medicine which slows your reactions, such as medicines to help you sleep or relieve pain, antidepressants, tranquillisers or antihistamines which can make you drowsy

What medications interact with Arrow-Topiramate?

Several medications interact with Arrow-Topiramate tablets 50mg and should either not be taken while you are taking Arrow-Topiramate or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction or increases side effects with Arrow-Topiramate: any medicine which slows your reactions (CNS depressants), such as medicines to help you sleep or relieve pain, antidepressants, tranquillisers or antihistamines which can make you drowsy and the effects may be worse when combines with Arrow-Topiramate; the anticonvulsant valproic acid can cause metabolic disturbances
  • Drugs that affect Arrow-Topiramate: other epilepsy medicines like phenytoin or carbamazepine; the diuretic hydrochlorothiazide
  • Drugs that are affected by Arrow-Topiramate; digoxin for heart failure; oral contraceptives; lithium and risperidone (for bipolar disorder and schizophrenia); metformin, pioglitazone, glibenclamide for diabetes

How should Arrow-Topiramate be taken?

You should take your Arrow-Topiramate tablets 50mg swallowed whole with a glass of water, with or without food, once daily preferably at the end of the day.  Your doctor will probably start you on a low dose and then increase your dose, which may be taken as 2 tablets morning and evening, depending on how well you respond, what you are being treated for and your doctor’s recommendation.  You should continue to take your Arrow-Topiramate tablets 50mg for as long as recommended by your doctor, which may be for several months or longer.  If your doctor recommends discontinuing taking Arrow-Topiramate 50mg, you will probably discontinue treatment gradually.

How long should you take Arrow-Topiramate?

You should continue to take your Arrow-Topiramate tablets 50mg for as long as recommended by your doctor, which may be for several months or longer.  If your doctor recommends discontinuing taking Arrow-Topiramate 50mg, you will probably discontinue treatment gradually.

Missed dose of Arrow-Topiramate

If you miss a dose of Arrow-Topiramate tablets 50mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Arrow-Topiramate be stored?

You should store your Arrow-Topiramate tablets 50mg below 25°C in a cool dry place. 

 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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