Nutra-Life Joint Care 120s
Nutra-Life Joint Care 120 Capsules/Pack
Dietary supplement (joint health)
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Joint Care general information
What is Joint Care used for?
Joint Food is a dietary supplement used to help maintain healthy joints and cartilage and to help prevent the progression of degenerative joint disease like osteoarthritis, commonly known as wear and tear. Cartilage plays an important role in providing a cushioning effect for bones at the joints and this protects the bones from rubbing against each other. As the joints age, or as a result of injury, cartilage degenerates and this can result in osteoarthritis, where bones are no longer cushioned, causing pain and inflammation, which leads to limited mobility of that joint. Joint Food helps protect cartilage from degradation by providing nutritional support for healthy joints to maintain cartilage and help reduce any further degradation.
How does Joint Care work?
Joint Care capsules contain a combination of glucosamine and chondroitin which are nutritional building blocks for normal cartilage formation. Glucosamine is an amino sugar that is naturally produced by the body as the first step in the hexosamine biosynthesis pathway, and is a precursor for making glycosaminoglycans (GAG). These are complex carbohydrate molecules that combine with protein to form proteoglycans such as chondroitin or form other molecules like hyaluronan which is a component of synovial fluid that lubricates joints. GAGs are important components of connective tissue particularly cartilage and tendons as they are part of the extracellular matrix that gives tensile strength to cartilage and they attract water molecules, which keeps cartilage hydrated and flexible and this helps to maintain its role as the “shock absorbers” of the joints. The combination of glucosamine and chondroitin in Joint Care helps slow the progression of destruction of articular cartilage (cartilage covering bones) caused by wear and tear of aging joints that can result in osteoarthritis, cartilage degeneration and erosion of the bone normally protected by cartilage1,2,3,4,5. During the aging process the ability to produce these important building blocks for joints is impaired and levels of GAGs are reduced, therefore supplementation with Joint Care can help restore levels of these joint nutrients so that the body is less dependent on production of glucosamine and chondroitin. The antioxidants and nutritional cofactors in Joint Care capsules also contribute to maintaining joint health and mobility. Clinical studies have shown that chondroitin (alone or in combination with glucosamine) was better than placebo in improving pain and preventing reduction in minimum joint space width in joints affected by osteoarthritis6. it has also been shown that glucosamine and chondroitin improve pain in knees with osteoarthritis and has an excellent safety profile3. In a randomised controlled trial comparing the efficacy of the combination of chondroitin and glucosamine with the anti-inflammatory celecoxib, it was shown that that the combination of chondroitin plus glucosamine was non-inferior to celecoxib in reducing pain in osteoarthritis, and therefore had comparable efficacy as a treatment for osteoarthritis7.
What does Joint Care contain?
Joint Care capsules contain the active ingredients glucosamine (sulphate, potassium chloride complex 750mg) and bovine chondroitin sulphate (250mg). They also contain copper gluconate (166mcg), manganese sulphate (1mg), zinc oxide (2mg) and Selenomethionine (12.5mcg) Ingredients are derived from shellfish.
Treating osteoarthritis with Joint Care
Joint Care capsules contain a combination of glucosamine and chondroitin which are nutritional building blocks for normal cartilage formation. As the joints age, or as a result of injury, cartilage degenerates and this can result in degenerative joint disease like osteoarthritis, commonly known as wear and tear, where bones are no longer cushioned, causing pain and inflammation, which leads to limited mobility of that joint. Joint Care helps maintain healthy joints and cartilage and helps restore and repair damaged cartilage, by providing the two important precursors for building healthy cartilage, glucosamine and chondroitin, which keeps cartilage hydrated and flexible and this helps to maintain its role as the “shock absorbers” of the joints. Joint Care also contains antioxidants and nutritional cofactors to provide protection from joint wear and tear. This combination of ingredients in Joint Care nourishes the joint tissues and helps with regeneration and repair, which reduces the pain and inflammation of osteoarthritis as well as improving joint flexibility. Clinical studies have shown that chondroitin and glucosamine are effective in slowing down the progression of joint destruction and reducing pain in osteoarthritis1-7.
What are the side effects of Joint Care?
The most commonly reported side effects when taking Joint Care capsules include: gastro-intestinal disturbance like gas, loose stools or nausea, also since glucosamine is a sugar it could contribute to fluctuating sugar and insulin levels in diabetics.
When should Joint Care not be used?
You should not use Joint Care capsules if you:
- are allergic to glucosamine or chondroitin or any ingredients in Joint Food
- are allergic to shellfish
- are pregnant or are breastfeeding
- have gout, high blood pressure or kidney disease, without discussion with your doctor
- have diabetes without discussion with your doctor
- are taking warfarin
What medications interact with Joint Care?
Glucosamine in Joint Care has the potential to interact with the anticoagulant warfarin, and therefore, Joint Care should either not be taken while you are taking warfarin or only after discussion and instruction from your doctor.
How should Joint Care be taken?
You should take your Joint Care capsules with a glass of water, 1-2 capsules daily with food or as directed by your healthcare professional; you should see benefits from 6 weeks to 3 months. You should continue to take your Joint Care capsules regularly and they can be taken long-term.
How long should you take Joint Care?
You should continue to take your Joint Care capsules regularly and they can be taken long-term.
Missed dose of Joint Care
If you miss a dose of Joint Care take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Joint Care be stored?
You should store your Joint Care below 25°C in a cool dry place and away from direct sunlight.
- Bruyere O, Reginster JY. Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis. Drugs Aging 2007;24(7):573-80.
- Black C, Clar C, Henderson R, MacEachern C, McNamee P, Quayyum Z, Royle P, Thomas S. The clinical effectiveness of glucosamine and chondroitin supplements in slowing or arresting progression of osteoarthritis of the knee: a systematic review and economic evaluation. Health Technology Assessment 2009; 13: 52 DOI: 10.3310/hta13520
- Vangsness CT, Spiker W, Erickson J. A review of evidence-based medicine for glucosamine and chondroitin sulfate use in knee osteoarthritis. Arthroscopy 2009; 25(1):86-94.
- Onuora S. Glucosamine–chondroitin combo improves knee OA pain. Nature Reviews Rheumatology 2015:11; 126; doi:10.1038/nrrheum.2015.9
- Bottegoni C, Muzzarelli RA, Giovannini F, Busilacchi A, Gigante A. Oral chondroprotection with nutraceuticals made of chondroitin sulphate plus glucosamine sulphate in osteoarthritis. Carbohydr Polym 2014 Aug 30;109:126-38. doi: 10.1016/j.carbpol.2014.03.033. Epub 2014 Mar 27.
- Singh JA, Noorbaloochi S, MacDonald R, Maxwell LJ. Chondroitin for osteoarthritis. Cochrane Database Syst Rev. 2015 Jan 28;1:CD005614. doi: 10.1002/14651858.CD005614.pub2.
- Hochberg MC,Martel-Pelletier J,Monfort J, Möller I,Castillo JR, Arden N, Berenbaum F, Blanco FJ, Conaghan PG, Doménech G, Henrotin Y, Pap T, Richette P, Sawitzke A, du Souich P, Pelletier JP; on behalf of the MOVES Investigation Group. Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis: a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib. Ann Rheum Dis. 2015 Jan 14. pii: annrheumdis-2014-206792. doi: 10.1136/annrheumdis-2014-206792. [Epub ahead of print]