100% Pure Colostrum Powder 100gm/Pack
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Colostrum general information
What is Colostrum used for?
100% Pure Colostrum powder is a nutritional supplement sourced from pasture fed New Zealand cows and is suitable for adults and children, to support immune function and promote digestive health. It is often known as “Nature’s superfood”. Colostrum is the first milk produced by mammals after birth of a newborn and contains high levels of nutrients, growth factors and immunoglobulins, providing protection against infection until the immune system of the newborn has matured. Bovine colostrum is rich source of immunoglobulins, about 10 times higher than human colostrum and was used as a source of immunoglobulin for the first oral polio vaccine1. Human immunoglobulins cross the placenta, providing passive immunity before birth, with continued protection provided by immunoglobulins in the colostrum. As well as providing passive immunity against opportunistic infections to the newborn calf, bovine colostrum is also a rich source of growth factors that promotes growth and development of the calf’s digestive tract2, 3. In several cultures, colostrum was traditionally fed to children and pregnant women as a health food and it has since been demonstrated that oral colostrum is rich in immunoglobulins as well as other bioactive ingredients and does have certain health-promoting properties4, 5, 6. Indications are that bovine Colostrum may have benefit in protection against enteric pathogens such as bacterial infections of the gut4, gastro-intestinal diseases like inflammatory bowel disease, nonsteroidal antiinflammatory drug–induced gut injury, and chemotherapy induced mucositis (inflammation and ulceration of the gut lining).5, 7, 8; also feeding of preterm infants if there is insufficient mother’s milk9.
How does Colostrum work?
100% Pure Colostrum contains several natural ingredients including immunoglobulins, growth factors and antimicrobials that provide certain clinically proven health benefits. The health benefits due to colostrum are mainly due to its antibacterial effect, including neutralising bacterial lipopolysaccharides, which are bacterial toxins that can cause health problems in the gut; also modulation of the immune response5, 6. Immunoglobulins are antibodies produced by B cells of the immune system. They are large glycoproteins that provide immunity against invading pathogens like bacteria and viruses by binding to the pathogen and neutralising it with the assistance of other cells of the immune system. The most common form of immunoglobulin is IgG. Other antibodies include IgE, which mediates the allergic response, and IgA which is found mainly associated with mucosal membranes like the gut.
Colostrum also contains other bioactive antimicrobial peptides2. Lactoferrin is a large glycoprotein present in high concentrations in both colostrum and milk and also in other secretions including tears and nasal secretions. It has antibacterial properties against several bacteria, including Escherichia coli, due to its ability to bind free iron, which is an essential substrate for bacterial growth, making it unavailable for the bacterial development; also by binding to certain receptors on the bacterial cell wall which causes bacterial death. Lactoferrin also has antiviral, antifungal and anti-parasitic properties10, 11, 12. As well as its antimicrobial effects, several studies have demonstrated that lactoferrin has anti-cancer properties thought to be due to its ability to interfere with several aspects of cancer cell growth and its immunomodulatory activities, as well as promoting apoptosis (programmed cell death)13.
Lactoperoxidase is an antibacterial peptide found in milk, saliva and tears is involved in the natural host defence system against pathogenic microorganisms. Lactoperoxidase is an enzyme that catalyses the production of several products that are toxic to bacteria but not harmful to their host14. It can inactivate some viruses including polio virus, vaccinia, and human immunodeficiency virus type-I in-vitro3.
Lysozyme is a lytic enzyme with antibacterial properties that is present in high concentrations in colostrum. It is effective against several gram-positive bacteria like bacillus and streptococcus and works by breaking down the peptidoglycans in bacterial cell walls, killing the bacteria.
Colostrum also contains other bioactive components such as growth factors, including Insulin-like Growth Factor I and II (IGF-I and IGF-II), Transforming Growth Factor beta (TGF beta) and Epidermal Growth Factor (EGF). Growth factors have many roles to play in cell growth and differentiation and may contribute to health benefits in certain gastrointestinal disorders 7. Colostrum also contains cytokines like interleukins which are involved in regulation of the immune system and may contribute to the immunoregulatory properties of colostrum2, 7.
What does Colostrum contain?
Colostrum powder contains the active ingredient IgG (15-20%). Each 3g serve (one rounded teaspoon) contains the following:
- Energy 46kJ
- Protein 1.8g
- Fat, total Less than 1g
- Fat saturated Less than 1g
- Carbohydrate Less than 1g
- Sugars Less than 1g
- Sodium 10mg
- IgG 0.5g
Colostrum for immune support and digestive health
100% Pure Colostrum is sourced from pasture fed New Zealand cows and is suitable for adults and children to support immune function. Colostrum provides protection against infection until the immune system of the newborn has matured and is a rich source of Immunoglobulin (IG) antibodies, particularly IgG, which is the most common form of immunoglobulin. Antibodies are produced by B cells of the immune system to protect against invading pathogens like bacteria and viruses. They work by binding to the pathogen and neutralising it with the assistance of other cells of the immune system. It is thought that that bovine Colostrum may have benefit in protection against enteric pathogens, which are bacteria that invade the gastrointestinal system and cause bacterial infections of the gut. Colostrum contains several bioactive antimicrobial proteins, including lactoferrin, lactoperoxidase and lysozyme which have antibacterial properties and work by either killing the bacteria or neutralising their toxins. Colostrum also contains cytokines like interleukins which are involved in regulation of the immune system and may contribute to the immunoregulatory properties of colostrum.
Colostrum for gastrointestinal conditions
Goodhealth 100% Pure Colostrum contains several bioactive components and clinical studies have indicated that Colostrum may have benefit in treatment of a wide variety of gastrointestinal conditions, including inflammatory bowel disease, nonsteroidal antiinflammatory drug induced gut injury, and chemotherapy induced mucositis (inflammation and ulceration of the gut lining). Growth factors like Insulin-like Growth Factor I and II (IGF-I and IGF-II), Transforming Growth Factor beta (TGF beta) and Epidermal Growth Factor (EGF) have many roles to play in cell growth and differentiation. These components of Goodhealth 100% Pure Colostrum may contribute to health benefits in certain gastrointestinal disorders by stimulating growth and repair of intestinal cells. Goodhealth 100% Pure Colostrum is sourced from pasture fed New Zealand cows and is suitable for adults and children to help with certain gastrointestinal conditions.
What are the side effects of Colostrum?
The most commonly reported side effects when taking Colostrum include lactose intolerance.
When should Colostrum not be used?
You should not use Colostrum if you:
- are allergic to lactose, soy (may be present n traces) or any ingredients in Colostrum
- have lactose intolerance
Colostrum is not suitable as a complete food for infants under 12 months
How should Colostrum be taken?
You should take your 100% Pure Colostrum powder once or twice daily by mixing with milk preferably on an empty stomach and as recommended by your health professional. The dose you take should be as recommended by your health professional, and is usually one teaspoon for adults and half a teaspoonful for children. You should not eat or take any other supplements for 20 minutes after taking 100% Pure Colostrum.
How long should you take Colostrum?
You should take your 100% Pure Colostrum for as long as recommended by your health professional.
Missed dose of Colostrum
If you miss a dose of 100% Pure Colostrum take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Colostrum be stored?
You should store your Colostrum below 25°C in a cool dry place.
- Sabin AB. Antipoliomyelitic substance in milk of human beings and certain cows. AMA Am J Dis Child 1950 Nov;80(5):866-7.
- Pakkanen R, Aalto J: Growth factors and antimicrobial factors of bovine colostrum. Int Diary J 1997, 7:285–297.
- Tripathi V, Vashishtha B. Bioactive compounds of colostrum and its application. Food Rev Int (2006) 22:225–44.
- Solomons NW. Modulation of the immune system and the response against pathogens with bovine colostrum concentrates. Eur J Clin Nutr 2002 Aug;56 Suppl 3:S24-8.
- Kelly GS. Bovine colostrums: a review of clinical uses. Altern Med Rev 2003 Nov;8(4):378-94.
- Struff WG, Sprotte G. Bovine colostrum as a biologic in clinical medicine: a review. Part I: biotechnological standards, pharmacodynamic and pharmacokinetic characteristics and principles of treatment. Int J Clin Pharmacol Ther 2007 Apr;45(4):193-202.
- Playford RJ, Macdonald CE, Johnson WS. Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders. Am J Clin Nutr 2000 Jul;72(1):5-14.
- Rathe M, Müller K, Sangild PT, Husby S. Clinical applications of bovine colostrum therapy: a systematic review. Nutr Rev 2014 Apr;72(4):237-54.
- Li Y, Juhl SM, Ye X, Shen RL, Iyore EO, Dai Y, Sangild PT, Greisen GO. A Stepwise, Pilot Study of Bovine Colostrum to Supplement the First Enteral Feeding in Preterm Infants (Precolos): Study Protocol and Initial Results. Front Pediatr 2017 Mar 3;5:42
- 10. Farnaud S, Evans RW. Lactoferrin--a multifunctional protein with antimicrobial properties. Mol Immunol 2003 Nov;40(7):395-405.
- Valenti P, Berlutti F, Conte MP, Longhi C, Seganti L. Lactoferrin functions: current status and perspectives. J Clin Gastroenterol. 2004 Jul;38(6 Suppl):S127-9.
- Orsi N. The antimicrobial activity of lactoferrin: current status and perspectives. Biometals 2004 Jun;17(3):189-96.
- Zhang Y, Lima CF, Rodrigues LR. Anticancer effects of lactoferrin: underlying mechanisms and future trends in cancer therapy. Nutr Rev 2014 Dec;72(12):763-73
- Koksal Z, Gulcin I, Ozdemir H. An Important Milk Enzyme: Lactoperoxidase. https://cdn.intechopen.com/pdfs-wm/51564.pdf