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High 5HTP Mood Support 100mg

High 5HTP Mood Support general information

What is High 5HTP Mood Support used for?

High 5HTP Mood Support capsules 100mg are a nutritional supplement used in the treatment of various conditions where serotonin is thought to play an important role and serotonin deficiency is thought to be a possible cause.  Serotonin is a neurotransmitter (brain chemical that allows nerve cells to communicate), which regulates many body activities, including sleep, appetite, temperature control, pain sensation, sexual behaviour as well as regulating mood.  High 5HTP Mood Support capsules 100mg have a wide range of applications and are used to support mental wellbeing, including low moods, stress and anxiety, help manage carbohydrate cravings and emotional eating, and improve poor sleeping habits for improved sleep quality.  Evidence from controlled clinical trials suggests that plant extract derived 5-HTP may be effective in treating symptoms of depression1, 2, 3  and in helping with appetite control in overweight subjects during a weight loss program4,5.  There is also some evidence that 5-HTP may also be of clinical benefit in relieving symptoms of fibromyalgia, including pain, stiffness and sleeplessness1,6.  

How does High 5HTP Mood Support work?

High 5HTP Mood Support capsules 100mg contain an extract of the seeds of Griffonia simplicifolia, a tropical shrub native to West Africa, whose seeds are rich in (5-Hydroxytryptophan) 5-HTP7.  5-HTP is is an intermediate metabolite in the biosynthesis of serotonin, a neurotransmitter (brain chemical that allows nerve cells to communicate), which regulates many body activities, including, appetite, temperature control, pain sensation, sexual behaviour, mood and sleep.  Griffonia simplicifolia seed extract has been used traditionally as an herbal remedy for sleep problems.  5-HTP is well absorbed into the blood from the gastrointestinal system and is not affected by food, therefore, it is readily available to cross into the brain where it can be used to synthesise serotonin1.  5-HTP is synthesised from the amino acid tryptophan, which is obtained from the diet.  Tryptophan is converted by the body to 5-HTP, which is an intermediate metabolite in the biosynthesis of serotonin and this takes place both in the central nervous system and in peripheral tissues.  Although serotonin is used in other cells in the body, such as platelets, the serotonin available to the brain must be synthesised within the brain cells or neurones, as serotonin cannot cross the blood brain barrier.  Both tryptophan and 5-HTP easily cross the blood brain barrier and are therefore, available for serotonin synthesis, which raises the amount of serotonin in the brain and in turn increases stimulation of nerve pathways that regulate mood, sleep and other processes.  Serotonin is also converted to melatonin, the hormone produced in the brain that coordinates the circadian rhythms, based on light/dark cycles, with biological processes including sleep.  5-HTP in High 5HTP Mood Support capsules 100mg extracted from Griffonia simplicifolia is thought to work by providing precursors for important chemicals, like serotonin and melatonin known to promote sleep, reduce anxiety and improve mood. 

What does High 5HTP Mood Support contain?

High 5HTP Mood Support contains the active ingredient 5-Hydroxytryptophan (5-HTP) 100mg, derived from the seed of the tropical shrub Griffonia simplicifolia, used to treat conditions due to low serotonin levels. 

High 5HTP Mood Support for mental and emotional wellbeing

High 5HTP Mood Support capsules 100mg contain 5-Hydroxytryptophan (5-HTP), derived from the seed of the tropical shrub Griffonia simplicifolia7 that is used as a nutritional supplement used in the treatment of various conditions where serotonin is thought to play an important role and serotonin deficiency is thought to be a possible cause.  Uses include supporting mental wellbeing, by improving low moods and reducing stress and anxiety, helping balance appetite by managing carbohydrate cravings and emotional eating, and improving poor sleeping habits for improved sleep quality.  Evidence from controlled clinical trials suggests that plant extract derived 5-HTP may be effective in treating symptoms of depression1, 2, 3  and in helping with appetite control in overweight subjects during a weight loss program4,5.  There is also some evidence that 5-HTP may also be of clinical benefit in relieving symptoms of fibromyalgia, including pain, stiffness and sleeplessness1,6.  Griffonia simplicifolia, a rich source of 5-HTP1, has been used traditionally as an herbal remedy for sleep problems.  5-HTP is an intermediate metabolite in the biosynthesis of serotonin, a neurotransmitter (brain chemical that allows nerve cells to communicate) that regulates many body activities, including, appetite, temperature control, pain sensation, sexual behaviour, mood and sleep.  5-HTP is well absorbed into the blood from the gastrointestinal system and is not affected by food, therefore, it is readily available to cross into the brain where it can be used to synthesise serotonin1.  Both tryptophan and 5-HTP easily cross the blood brain barrier and are therefore, available for serotonin synthesis, which raises the amount of serotonin in the brain and in turn increases stimulation of nerve pathways that regulate mood, sleep and other processes.  Serotonin is also converted to melatonin, the hormone produced in the brain that coordinates the circadian rhythms, based on light/dark cycles, with biological processes including sleep.  5-HTP in High 5HTP Mood Support capsules 100mg extracted from Griffonia simplicifolia is thought to work by providing precursors for important chemicals, like serotonin and melatonin known to promote sleep, reduce anxiety and improve mood. 

What are the side effects of High 5HTP Mood Support?

The most commonly reported side effects when taking High 5HTP Mood Support capsules 100mg include nausea, diarrhoea dizziness, and drowsiness.  High levels of serotonin can cause Serotonin Syndrome, with symptoms including, nausea, diarrhoea, dizziness, sweating, increased heart rate and can cause agitation or restlessness fever and seizures. 

When should High 5HTP Mood Support not be used?

You should not use High 5HTP Mood Support capsules 100mg if you:

  • are allergic to 5-HTP or any ingredients in High 5HTP Mood Support
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • are taking medicines that interact with High 5HTP Mood Support, including SSRI and MOI antidepressants, cabidopa for Parkinson’s disease, narcotics, cough medicine containing dextromethorphan, herbal supplements that can cause drowsiness like St John’s Wort

What medications interact with High 5HTP Mood Support?

Several medications interact with High 5HTP Mood Support capsules 100mg and should either not be taken while you are taking High 5HTP Mood Support or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with High 5HTP Mood Support: cabidopa for Parkinson’s disease, SSRI and MOI antidepressants, narcotics, cough medicine containing dextromethorphan, herbal supplements that can cause drowsiness like St John’s Wort
  • Drugs that are affected by High 5HTP Mood Support: cabidopa for Parkinson’s disease

How should High 5HTP Mood Support be taken?

You should take your High 5HTP Mood Support capsules 100mg with a glass of water at night.  The dose you take should be as recommended by your healthcare professional and is usually 1-3 capsules daily.  You should continue to use High 5HTP Mood Support capsules 100mg for as long as directed by your healthcare professional.

How long should you take High 5HTP Mood Support?

You should continue to use High 5HTP Mood Support capsules 100mg for as long as directed by your healthcare professional.

Missed dose of High 5HTP Mood Support

If you miss a dose of High 5HTP Mood Support capsules 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should High 5HTP Mood Support be stored?

You should store your High 5HTP Mood Support below 25°C in a cool dry place. 

 References

  1. Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev 1998; 3: 271-80.
  2. Turner EH, Loftis JM, Blackwell AD. Pharmacol Ther. 2006;109: 325-38. Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan.
  3. Shaw K, Turner J, Del Mar C. Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst Rev. 2002;(1):CD003198.
  4. Rondanelli M, Klersy C, Iadarola P, Monteferrario F, Opizzi A. Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation. Int J Obes 2009;33:1174-82.
  5. Rondanelli M, Opizzi A, Faliva M, Bucci M, Perna S. Relationship between the absorption of 5-hydroxytryptophan from an integrated diet, by means of Griffonia simplicifolia extract, and the effect on satiety in overweight females after oral spray administration. Eat Weight Disord. 2012 Mar;17(1):e22-8. doi: 10.3275/8165
    https://www.ncbi.nlm.nih.gov/pubmed/22142813
  6. Sarzi Puttini P, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study.  J Int Med Res.1992;20:182-9.
  7. Lemaire P, Adosraku RK. An HPLC method for the direct assay of the serotonin precursor, 5-hydroxytrophan, in seeds of Griffonia simplicifolia.  Phytochem Anal. 2002;13: 333-7.
Good HealthNutritional supplement
GBPInhousePharmacy.vuNewOut of Stock1High 5HTP 100mg 60 Capsules/Pack
High 5HTP Mood Support 100mg


High 5HTP Mood Support 100mg

High 5HTP Mood Support 100mg

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Product Name
High 5HTP 100mg 60 Capsules/Pack
5HTP supports mental wellbeing
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Nutritional supplement
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Good Health
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Nutritional supplement
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High 5HTP 100mg 60 Capsules
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High 5HTP Mood Support capsules 100mg contain 5-Hydroxytryptophan.  They are a nutritional supplement used to support mood balance and sleep quality, manage appetite and reduce stress and anxiety. 

High 5HTP Mood Support general information

What is High 5HTP Mood Support used for?

High 5HTP Mood Support capsules 100mg are a nutritional supplement used in the treatment of various conditions where serotonin is thought to play an important role and serotonin deficiency is thought to be a possible cause.  Serotonin is a neurotransmitter (brain chemical that allows nerve cells to communicate), which regulates many body activities, including sleep, appetite, temperature control, pain sensation, sexual behaviour as well as regulating mood.  High 5HTP Mood Support capsules 100mg have a wide range of applications and are used to support mental wellbeing, including low moods, stress and anxiety, help manage carbohydrate cravings and emotional eating, and improve poor sleeping habits for improved sleep quality.  Evidence from controlled clinical trials suggests that plant extract derived 5-HTP may be effective in treating symptoms of depression1, 2, 3  and in helping with appetite control in overweight subjects during a weight loss program4,5.  There is also some evidence that 5-HTP may also be of clinical benefit in relieving symptoms of fibromyalgia, including pain, stiffness and sleeplessness1,6.  

How does High 5HTP Mood Support work?

High 5HTP Mood Support capsules 100mg contain an extract of the seeds of Griffonia simplicifolia, a tropical shrub native to West Africa, whose seeds are rich in (5-Hydroxytryptophan) 5-HTP7.  5-HTP is is an intermediate metabolite in the biosynthesis of serotonin, a neurotransmitter (brain chemical that allows nerve cells to communicate), which regulates many body activities, including, appetite, temperature control, pain sensation, sexual behaviour, mood and sleep.  Griffonia simplicifolia seed extract has been used traditionally as an herbal remedy for sleep problems.  5-HTP is well absorbed into the blood from the gastrointestinal system and is not affected by food, therefore, it is readily available to cross into the brain where it can be used to synthesise serotonin1.  5-HTP is synthesised from the amino acid tryptophan, which is obtained from the diet.  Tryptophan is converted by the body to 5-HTP, which is an intermediate metabolite in the biosynthesis of serotonin and this takes place both in the central nervous system and in peripheral tissues.  Although serotonin is used in other cells in the body, such as platelets, the serotonin available to the brain must be synthesised within the brain cells or neurones, as serotonin cannot cross the blood brain barrier.  Both tryptophan and 5-HTP easily cross the blood brain barrier and are therefore, available for serotonin synthesis, which raises the amount of serotonin in the brain and in turn increases stimulation of nerve pathways that regulate mood, sleep and other processes.  Serotonin is also converted to melatonin, the hormone produced in the brain that coordinates the circadian rhythms, based on light/dark cycles, with biological processes including sleep.  5-HTP in High 5HTP Mood Support capsules 100mg extracted from Griffonia simplicifolia is thought to work by providing precursors for important chemicals, like serotonin and melatonin known to promote sleep, reduce anxiety and improve mood. 

What does High 5HTP Mood Support contain?

High 5HTP Mood Support contains the active ingredient 5-Hydroxytryptophan (5-HTP) 100mg, derived from the seed of the tropical shrub Griffonia simplicifolia, used to treat conditions due to low serotonin levels. 

High 5HTP Mood Support for mental and emotional wellbeing

High 5HTP Mood Support capsules 100mg contain 5-Hydroxytryptophan (5-HTP), derived from the seed of the tropical shrub Griffonia simplicifolia7 that is used as a nutritional supplement used in the treatment of various conditions where serotonin is thought to play an important role and serotonin deficiency is thought to be a possible cause.  Uses include supporting mental wellbeing, by improving low moods and reducing stress and anxiety, helping balance appetite by managing carbohydrate cravings and emotional eating, and improving poor sleeping habits for improved sleep quality.  Evidence from controlled clinical trials suggests that plant extract derived 5-HTP may be effective in treating symptoms of depression1, 2, 3  and in helping with appetite control in overweight subjects during a weight loss program4,5.  There is also some evidence that 5-HTP may also be of clinical benefit in relieving symptoms of fibromyalgia, including pain, stiffness and sleeplessness1,6.  Griffonia simplicifolia, a rich source of 5-HTP1, has been used traditionally as an herbal remedy for sleep problems.  5-HTP is an intermediate metabolite in the biosynthesis of serotonin, a neurotransmitter (brain chemical that allows nerve cells to communicate) that regulates many body activities, including, appetite, temperature control, pain sensation, sexual behaviour, mood and sleep.  5-HTP is well absorbed into the blood from the gastrointestinal system and is not affected by food, therefore, it is readily available to cross into the brain where it can be used to synthesise serotonin1.  Both tryptophan and 5-HTP easily cross the blood brain barrier and are therefore, available for serotonin synthesis, which raises the amount of serotonin in the brain and in turn increases stimulation of nerve pathways that regulate mood, sleep and other processes.  Serotonin is also converted to melatonin, the hormone produced in the brain that coordinates the circadian rhythms, based on light/dark cycles, with biological processes including sleep.  5-HTP in High 5HTP Mood Support capsules 100mg extracted from Griffonia simplicifolia is thought to work by providing precursors for important chemicals, like serotonin and melatonin known to promote sleep, reduce anxiety and improve mood. 

What are the side effects of High 5HTP Mood Support?

The most commonly reported side effects when taking High 5HTP Mood Support capsules 100mg include nausea, diarrhoea dizziness, and drowsiness.  High levels of serotonin can cause Serotonin Syndrome, with symptoms including, nausea, diarrhoea, dizziness, sweating, increased heart rate and can cause agitation or restlessness fever and seizures. 

When should High 5HTP Mood Support not be used?

You should not use High 5HTP Mood Support capsules 100mg if you:

  • are allergic to 5-HTP or any ingredients in High 5HTP Mood Support
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • are taking medicines that interact with High 5HTP Mood Support, including SSRI and MOI antidepressants, cabidopa for Parkinson’s disease, narcotics, cough medicine containing dextromethorphan, herbal supplements that can cause drowsiness like St John’s Wort

What medications interact with High 5HTP Mood Support?

Several medications interact with High 5HTP Mood Support capsules 100mg and should either not be taken while you are taking High 5HTP Mood Support or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with High 5HTP Mood Support: cabidopa for Parkinson’s disease, SSRI and MOI antidepressants, narcotics, cough medicine containing dextromethorphan, herbal supplements that can cause drowsiness like St John’s Wort
  • Drugs that are affected by High 5HTP Mood Support: cabidopa for Parkinson’s disease

How should High 5HTP Mood Support be taken?

You should take your High 5HTP Mood Support capsules 100mg with a glass of water at night.  The dose you take should be as recommended by your healthcare professional and is usually 1-3 capsules daily.  You should continue to use High 5HTP Mood Support capsules 100mg for as long as directed by your healthcare professional.

How long should you take High 5HTP Mood Support?

You should continue to use High 5HTP Mood Support capsules 100mg for as long as directed by your healthcare professional.

Missed dose of High 5HTP Mood Support

If you miss a dose of High 5HTP Mood Support capsules 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should High 5HTP Mood Support be stored?

You should store your High 5HTP Mood Support below 25°C in a cool dry place. 

 References

  1. Birdsall TC. 5-Hydroxytryptophan: a clinically-effective serotonin precursor. Altern Med Rev 1998; 3: 271-80.
  2. Turner EH, Loftis JM, Blackwell AD. Pharmacol Ther. 2006;109: 325-38. Serotonin a la carte: supplementation with the serotonin precursor 5-hydroxytryptophan.
  3. Shaw K, Turner J, Del Mar C. Tryptophan and 5-hydroxytryptophan for depression. Cochrane Database Syst Rev. 2002;(1):CD003198.
  4. Rondanelli M, Klersy C, Iadarola P, Monteferrario F, Opizzi A. Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation. Int J Obes 2009;33:1174-82.
  5. Rondanelli M, Opizzi A, Faliva M, Bucci M, Perna S. Relationship between the absorption of 5-hydroxytryptophan from an integrated diet, by means of Griffonia simplicifolia extract, and the effect on satiety in overweight females after oral spray administration. Eat Weight Disord. 2012 Mar;17(1):e22-8. doi: 10.3275/8165
    https://www.ncbi.nlm.nih.gov/pubmed/22142813
  6. Sarzi Puttini P, Caruso I. Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study.  J Int Med Res.1992;20:182-9.
  7. Lemaire P, Adosraku RK. An HPLC method for the direct assay of the serotonin precursor, 5-hydroxytrophan, in seeds of Griffonia simplicifolia.  Phytochem Anal. 2002;13: 333-7.
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