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General

Our General group of Pet Care products contains a drug for treating urinary incontinence in dogs, particularly spayed female dogs.

Use the search feature to quickly find the product you are looking for by entering either the active ingredient, e.g. phenylpropanolamine; or the product name e.g. Propalin.

Urinary incontinence and its treatment

Urinary incontinence is the loss of voluntary control of urination due to weakness or loss of muscle tone in the urethral sphincter, which is the muscle that controls urine flow out of the bladder. This condition is most common in older medium to large spayed female dogs and one cause is a malfunction of nerves in the part of the nervous system that controls urination. An effective treatment for this form of urinary incontinence is a syrup containing the drug phenylpropanolamine that works by acting as an alpha-adrenergic agonist and stimulates the nerves of the sympathetic nervous system. These nerve cells respond to catecholamine neurotransmitters (chemical used by nerve cells to communicate) like adrenaline. Phenylpropanolamine stimulates the alpha-adrenergic receptors in urethral muscle cells which increase muscle tone and results in tightening of the urethra which prevents urine leakage.
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""Excellent service, genuine items. And incredible savings over what I pay even with insurance.""
Wendy CA, USA • February 2021
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Deborah FL, USA • March 2023
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"Thank You for the Professional and Prompt way you have handled my missing shipment.  I have been doing business with you for a long time and I so much appreciate when a company values their customers and addresses issues in such a caring way and with such integrity.  I will be doing business with you for a very long time to come.  Thank You again."
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Richard GA, USA • October 2020
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"Order received - thanks for excellent service!"
Fred MO, USA • February 2024
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"Great service! Products are absolutely the best! I have been ordering from them for many, many years"
Rebecca MO, USA • October 2021
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""Your the best. Thank you" "
Ralph FL, USA • February 2021
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"Been with you since 1996. Always good products, and service."
Mary WA, USA • March 2023
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"I have been a customer for a few years, and will continue to stay. Orders are processed quickly, and delivery is excellent. Thank you all very much. "
EDDIE FL, USA • October 2021
 

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