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Mood Enhancer

Our Mood Enhancer class of antidepressants contains several medications that work by different mechanisms and are used to relieve symptoms of depression and other mood disorders and help prevent relapse.

Use the search feature to quickly find the product you are looking for by entering either the active ingredient, e.g. venlafaxine; or the product name e.g. Venlor.

...Read more
Our Mood Enhancer class of antidepressants contains several medications that work by different mechanisms and are used to relieve symptoms of depression and other mood disorders and help prevent relapse.

Use the search feature to quickly find the product you are looking for by entering either the active ingredient, e.g. venlafaxine; or the product name e.g. Venlor.

...Read more

APO-Escitalopram 10mg
APO-Escitalopram 10mg

Escitalopram
Also known as Lexapro or Cipralex
From $0.86 per Tablet
Loxamine 20mg (Paroxetine)
Loxamine 20mg (Paroxetine)

Paroxetine 20mg
Also known as Paxil
From $0.78 per Tablet
S Citadep (Escitalopram 5mg) Tablets
S Citadep (Escitalopram 5mg) Tablets

Escitalopram
Also known as Lexapro or Cipralex
Out Of Stock
Xet 20mg (Paroxetine)
Xet 20mg (Paroxetine)

Paroxetine
Also known as Paxil
From $1.15 per Tablet
APO-Escitalopram (Escitalopram 20mg)
APO-Escitalopram (Escitalopram 20mg)

Escitalopram
Also known as Lexapro or Cipralex
From $1.00 per Tablet
APO-Mirtazapine 30mg
APO-Mirtazapine 30mg

Mirtazapine 30mg
Also known as Remeron
From $0.87 per Tablet
APO-Paroxetine 20mg Tablets
APO-Paroxetine 20mg Tablets

Paroxetine
Also known as Aropax or Paxil
Out Of Stock
Brintellix (Vortioxetine 20mg)
Brintellix (Vortioxetine 20mg)
Vortioxetine
Also known as Trintellix
Out Of Stock
S Citadep 10mg (Escitalopram)
S Citadep 10mg (Escitalopram)

escitalopram
Also known as Lexapro or Cipralex
From $0.92 per Tablet
Cipramil 20mg 28 Tablets/Pack
Cipramil 20mg 28 Tablets/Pack
Citalopram hydrobromide
Also known as Celexa
From $2.72 per Tablet
Citalopram 20mg
Citalopram 20mg

Citalopram 20mg
Also known as Celexa or Cipramil
From $0.65 per Tablet
S Citadep 20mg (Escitalopram)
S Citadep 20mg (Escitalopram)

escitalopram
Also known as Lexapro or Cipralex
From $1.15 per Tablet
Depsonil (Imipramine 25mg)
Depsonil (Imipramine 25mg)
On Sale

Imipramine
Also known as Tofranil
From $0.20 per Tablet
Edronax (Reboxetine 4mg)
Edronax (Reboxetine 4mg)
Reboxetine
Discontinued
Efexor XR 75mg
Efexor XR 75mg
Venlafaxine
From $1.33 per Capsule
Venlor XR 75mg
Venlor XR 75mg

Venlafaxine
Also known as Efexor
Out Of Stock
Efexor XR 150mg
Efexor XR 150mg
Venlafaxine
From $1.54 per Capsule
Venlor XR 150mg
Venlor XR 150mg

Venlafaxine
Also known as Efexor
Out Of Stock
Enlafax XR (Venlafaxine 37.5mg)
Enlafax XR (Venlafaxine 37.5mg)

Venlafaxine
Also known as Effexor or Efexor
From $0.59 per Capsule
Enlafax XR (Venlafaxine 75mg)
Enlafax XR (Venlafaxine 75mg)

Venlafaxine
Also known as Effexor or Efexor
From $0.69 per Capsule
Enlafax XR (Venlafaxine 150mg)
Enlafax XR (Venlafaxine 150mg)

Venlafaxine
Also known as Effexor or Efexor
From $0.71 per Capsule
Fluoxetine Dispersible 20mg
Fluoxetine Dispersible 20mg

Fluoxetine
Out Of Stock
Fluvoxin 50 (Fluvoxamine maleate 50mg) Tablets
Fluvoxin 50 (Fluvoxamine maleate 50mg) Tablets

Fluvoxamine maleate
Also known as Luvox
From $0.85 per Tablet
Fluvoxin 100 (Fluvoxamine maleate 100mg) Tablets
Fluvoxin 100 (Fluvoxamine maleate 100mg) Tablets

Fluvoxamine maleate
Also known as Luvox
From $1.13 per Tablet
Fluvoxin CR 50 (Fluvoxamine maleate 50mg) Tablets
Fluvoxin CR 50 (Fluvoxamine maleate 50mg) Tablets

Fluvoxamine maleate
Also known as Luvox
From $0.87 per Tablet
Fluvoxin CR 100 (Fluvoxamine maleate 100mg) Tablets
Fluvoxin CR 100 (Fluvoxamine maleate 100mg) Tablets

Fluvoxamine maleate
Also known as Luvox
From $1.20 per Tablet
Newven (Desvenlafaxine 100mg)
Newven (Desvenlafaxine 100mg)

Desvenlafaxine
Also known as Pristiq or Prestiq
From $0.99 per Tablet
Newven (Desvenlafaxine 50mg)
Newven (Desvenlafaxine 50mg)

Desvenlafaxine
Also known as Pristiq or Prestiq
From $0.68 per Tablet
Paxil (Paroxetine 20mg) (Sourced from Turkey)
Paxil (Paroxetine 20mg) (Sourced from Turkey)
Paroxetine
Original branded product (Turkish writing) - comes with English language leaflet.
Out Of Stock
Prozac 20mg
Prozac 20mg
Fluoxetine
From $2.31 per Capsule
Elevat 20mg (Fluoxetine)
Elevat 20mg (Fluoxetine)

Fluoxetine 20 mg
Also known as Prozac
From $0.75 per Capsule
Fludac 20mg (Fluoxetine) 15's
Fludac 20mg (Fluoxetine) 15's

Fluoxetine 20 mg
Also known as Prozac
From $0.75 per Capsule
Prozac 20mg (Sourced from Turkey)
Prozac 20mg (Sourced from Turkey)
Fluoxetine
Original branded product (Turkish writing) - comes with English language leaflet.
Out Of Stock
Setrona (Sertraline 50mg) Tablets
Setrona (Sertraline 50mg) Tablets

Sertraline
Also known as Zoloft
Out Of Stock
Zosert 50mg (sertraline)
Zosert 50mg (sertraline)

Sertraline
Also known as Zoloft
Out Of Stock
Sertraline 50
Sertraline 50

Sertraline
Also known as Zoloft
Discontinued
Setrona (Sertraline 100mg) Tablets
Setrona (Sertraline 100mg) Tablets

Sertraline
Also known as Zoloft
From $0.74 per Tablet
Stablon (Tianeptine 12.5mg)
Stablon (Tianeptine 12.5mg)

Tianeptine 12.5mg
From $0.82 per Tablet
Symbal 20mg (Duloxetine)
Symbal 20mg (Duloxetine)

Duloxetine
Also known as Cymbalta
Out Of Stock
Symbal 30mg (Duloxetine)
Symbal 30mg (Duloxetine)

Duloxetine
Also known as Cymbalta
Out Of Stock
Symbal 60mg (Duloxetine)
Symbal 60mg (Duloxetine)

Duloxetine
Also known as Cymbalta
From $1.44 per Tablet
Tofranil 10mg (Imipramine)
Tofranil 10mg (Imipramine)
Imipramine
From $0.48 per Tablet
Tofranil 25mg (Imipramine)
Tofranil 25mg (Imipramine)
Imipramine
From $0.49 per Tablet
Venlor XR 37.5mg
Venlor XR 37.5mg

Venlafaxine
Also known as Efexor
From $0.96 per Capsule
Zoloft 100mg
Zoloft 100mg
Sertraline
From $5.84 per Tablet
Zosert 100 (Sertraline)
Zosert 100 (Sertraline)

Sertraline
Also known as Zoloft
Out Of Stock
Sertraline 100
Sertraline 100

Sertraline
Also known as Zoloft
Discontinued
APO-Mirtazapine 45mg
APO-Mirtazapine 45mg

Mirtazapine 45mg
Also known as Remeron
From $0.96 per Tablet

Symptoms of depression

Depression, also known as clinical depression, major depression or major depressive disorder, is characterised by symptoms including anxiety, loss of interest in activities that are usually pleasurable, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. If these symptoms continue for more than two weeks this suggests that the depression is a clinical condition and not just feeling low. Once an episode of major depression has occurred there is a high risk of recurrence of another depressive episode. Mood enhancing medications are used to treat depressive episodes and are also used as maintenance against relapse or recurrence of depressive episode.

Mood enhancing neurotransmitters

Serotonin and noradrenaline are the two most important neurotransmitters in the area of the brain that regulates mood. When serotonin or noradrenaline is released from one nerve cell it passes across the gap between nerve cells (synapse) and fires up the next nerve cell. This sets up a communication signal that is transmitted from one nerve cell to another. If there is not sufficient serotonin or noradrenaline released to trigger this nerve signal, then this communication pathway does not work properly and can lead to symptoms of depression.

Inhibition of neurotransmitter reuptake

Both serotonin and noradrenaline are recycled after use by being taken back up into the presynaptic neurone or sending cell. Serotonin noradrenaline reuptake inhibitors (SNRIs) work by inhibiting the reuptake of both serotonin and noradrenaline, whereas the selective serotonin reuptake inhibitors (SSRI) are very selective for serotonin and do not affect other neurotransmitters. SNRIs also have a small effect on other neurotransmitters like dopamine. If neurotransmitter reuptake is inhibited, there is more serotonin or noradrenaline remaining in the synapse to trigger the next cell and continue communication between mood-enhancing neurones.

Tricyclic antidepressants also work by inhibiting neurotransmitter reuptake, however, they non-specific in their action as they also affect several other brain chemicals like histamine and acetylcholine, which accounts for their sedative properties and other side effects.

Reversible inhibitors of monoamine oxidase

Reversible inhibitors of monoamine oxidase (RIMA) antidepressants work by a different mechanism from other classes of antidepressant to boost the amount of mood enhancing neurotransmitters. Once they have done their job by stimulating a nerve impulse, neurotransmitters are removed and one way this is done is by being inactivated by the enzyme monoamine oxidase. Inhibition of monoamine oxidase results in more serotonin and noradrenaline remaining to trigger the next cell and continue communication between mood-enhancing neurones. RIMAs are short lived and their effects reversible so they do not have such serious side effects as earlier drugs.
 ...Read more

Symptoms of depression

Depression, also known as clinical depression, major depression or major depressive disorder, is characterised by symptoms including anxiety, loss of interest in activities that are usually pleasurable, disturbed sleep, change in appetite, fatigue, feelings of worthlessness or guilt, difficulty thinking or concentrating, and recurrent thoughts of suicide. If these symptoms continue for more than two weeks this suggests that the depression is a clinical condition and not just feeling low. Once an episode of major depression has occurred there is a high risk of recurrence of another depressive episode. Mood enhancing medications are used to treat depressive episodes and are also used as maintenance against relapse or recurrence of depressive episode.

Mood enhancing neurotransmitters

Serotonin and noradrenaline are the two most important neurotransmitters in the area of the brain that regulates mood. When serotonin or noradrenaline is released from one nerve cell it passes across the gap between nerve cells (synapse) and fires up the next nerve cell. This sets up a communication signal that is transmitted from one nerve cell to another. If there is not sufficient serotonin or noradrenaline released to trigger this nerve signal, then this communication pathway does not work properly and can lead to symptoms of depression.

Inhibition of neurotransmitter reuptake

Both serotonin and noradrenaline are recycled after use by being taken back up into the presynaptic neurone or sending cell. Serotonin noradrenaline reuptake inhibitors (SNRIs) work by inhibiting the reuptake of both serotonin and noradrenaline, whereas the selective serotonin reuptake inhibitors (SSRI) are very selective for serotonin and do not affect other neurotransmitters. SNRIs also have a small effect on other neurotransmitters like dopamine. If neurotransmitter reuptake is inhibited, there is more serotonin or noradrenaline remaining in the synapse to trigger the next cell and continue communication between mood-enhancing neurones.

Tricyclic antidepressants also work by inhibiting neurotransmitter reuptake, however, they non-specific in their action as they also affect several other brain chemicals like histamine and acetylcholine, which accounts for their sedative properties and other side effects.

Reversible inhibitors of monoamine oxidase

Reversible inhibitors of monoamine oxidase (RIMA) antidepressants work by a different mechanism from other classes of antidepressant to boost the amount of mood enhancing neurotransmitters. Once they have done their job by stimulating a nerve impulse, neurotransmitters are removed and one way this is done is by being inactivated by the enzyme monoamine oxidase. Inhibition of monoamine oxidase results in more serotonin and noradrenaline remaining to trigger the next cell and continue communication between mood-enhancing neurones. RIMAs are short lived and their effects reversible so they do not have such serious side effects as earlier drugs.
 ...Read more

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