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Home > Digestive > Bowel

Bowel

Our Bowel class of Digestive medications used to treat of disorders the bowel (lower GI tract) like Inflammatory bowel disease and Irritable bowel syndrome, caused by inflammation, immune system dysfunction, stress, muscle spasm and infection; also constipation due to dysmobility of the intestine.

Use the search feature to quickly find the product you are looking for, by entering either the active ingredient, e.g. mesalazine or the product name, e.g. Asacol.

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Asacol 400mg (Mesalazine)
Mesalazine
Also known as Azacol or Pentasa
From $0.86 per Tablet

Colofac 135mg (Mebeverine)
Mebeverine
From $0.44 per Tablet

Creon 25000 (Pancreatic Enzymes )
Pancreatic Enzymes
From $1.66 per Capsule

Creon 10000 (Pancreatin 150mg)
Pancreatin 150mg
From $0.63 per Capsule

Dipentum 250mg (Olsalazine)
Olsalazine
If you need a higher quantity for 90 days supply, please call customer services for assistance.
From $1.10 per Capsule

Budez CR 3mg (Budesonide)

Budesonide
Also known as Entocort
From $1.47 per Tablet

Entocort 3mg (Budesonide)
Budesonide
Modified Release Capsules
From $3.58 per Capsule

Mesacol 400mg (Mesalamine)

Mesalamine (delayed release)
Out Of Stock

Mesacol 800mg (Mesalamine)

Mesalamine (delayed release)
Out Of Stock

Mesacol (Mesalamine (delayed release) 400mg) Tablets

Mesalamine (delayed release)
From $0.78 per Tablet

Mesacol (Mesalamine (delayed release) 800mg) Tablets

Mesalamine (delayed release)
From $1.00 per Tablet

Nalcrom 100mg (Sodium Cromoglycate)
Sodium Cromoglycate
Also known as Gastrocrom
From $1.44 per Capsule

Mesacol OD (Mesalamine (delayed release) 1200mg)

Mesalamine (delayed release)
Also known as Lialda
From $1.30 per Tablet

Pentasa 500mg (Mesalazine)
Mesalazine
From $1.19 per Tablet

Pro-Banthine 15mg
Propantheline bromide B.P. 15mg
Out Of Stock

Resolor (Prucalopride 1mg) Tablets
Prucalopride
Also known as Resotran or Motegrity
From $2.99 per Tablet

Resolor (Prucalopride 2mg) Tablets
Prucalopride
Also known as Resotran or Motegrity
Out Of Stock

Salazopyrin 500mg (Sulphasalazine)
Sulphasalazine
From $0.30 per Tablet

Salazopyrin-EN 500mg (Sulphasalazine)
Sulphasalazine EN
Enteric Coated Tablets
From $0.36 per Tablet

Inflammatory bowel diseases

Inflammatory bowel disease (IBD) is a group of disorders caused by chronic inflammation of the intestines. The two most common forms of IBD are Crohn's Disease, which can affect any part of the upper or lower GI tract, and ulcerative colitis that affects only the large intestine or colon and rectum. Both diseases are thought to be autoimmune diseases due to an over-reactive immune system, when the immune system attacks self, in this case, intestinal tissue. Symptoms vary from mild to severe when inflammation flares up with symptoms including, abdominal pain and cramping, rectal bleeding, diarrhoea and vomiting. Medications used for treating IBD to relieve symptoms include:

Anti-inflammatory drugs like Mesalazine that inhibit the cyclo-oxygenase enzyme (COX) and block the production of inflammatory chemicals like prostaglandins and leukotrienes, which also inhibits the migration of inflammatory cells like macrophages into intestine wall.

Immunomodifiers like sulphasalazine, which have anti-inflammatory, immunomodulatory and immunosuppressive effects and work by several different mechanisms, including, inhibiting production of inflammatory chemicals like prostaglandins and leukotrienes, which are also involved in immune reactions, influencing white cell function and inhibiting antibody production.

Corticosteroids like budesonide, which are also anti-inflammatory but work by a different mechanism, binding to a glucocorticosteroid receptor in the intestinal cells and inhibiting the production of inflammatory cytokines and cytokine-mediated immune responses.

Irritable bowel syndrome

Irritable bowel syndrome (IBS) covers a range of functional bowel disorders and includes conditions like chronic irritable colon (spastic colon), spastic constipation, spastic colitis and nervous diarrhoea. IBS has no specific cause but may be triggered by several factors, including food sensitivity, stress and infection. Symptoms are caused by spasm of the intestinal muscle as it squeezes food through the intestine and include abdominal pain and cramps, diarrhoea (with or without alternating constipation) and flatulence (wind). Medications used for treating IBD include:

Antispasmodics like mebeverine and propantheline that are both anticholinergic and work primarily by blocking the action of the neurotransmitter acetylcholine that is involved in regulating intestinal smooth muscle contraction. This action allows the smooth muscle to relax, reducing muscle spasm.

Serotonin agonists like tegaserod that also regulate intestinal smooth muscle contraction by binding to specific serotonin receptors found only in the nerve cells of the GI tract and this helps restore normal bowel motility; it also helps reduce sensitivity to pain and discomfort caused by symptoms of IBS.

Constipation

Chronic constipation may be a symptom of several GI disorders and is characterised by hard stools that are difficult to pass and infrequent bowel movements. Laxatives like lactulose help soften the stools by changing the osmotic pressure in the colon and allowing water to be drawn into the colon, which also increases bowel motility and makes the stools easier to pass.
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Inflammatory bowel diseases

Anti-inflammatory drugs like Mesalazine that inhibit the cyclo-oxygenase enzyme (COX) and block the production of inflammatory chemicals like prostaglandins and leukotrienes, which also inhibits the migration of inflammatory cells like macrophages into intestine wall.

Immunomodifiers like sulphasalazine, which have anti-inflammatory, immunomodulatory and immunosuppressive effects and work by several different mechanisms, including, inhibiting production of inflammatory chemicals like prostaglandins and leukotrienes, which are also involved in immune reactions, influencing white cell function and inhibiting antibody production.

Corticosteroids like budesonide, which are also anti-inflammatory but work by a different mechanism, binding to a glucocorticosteroid receptor in the intestinal cells and inhibiting the production of inflammatory cytokines and cytokine-mediated immune responses.

Irritable bowel syndrome

Antispasmodics like mebeverine and propantheline that are both anticholinergic and work primarily by blocking the action of the neurotransmitter acetylcholine that is involved in regulating intestinal smooth muscle contraction. This action allows the smooth muscle to relax, reducing muscle spasm.

Serotonin agonists like tegaserod that also regulate intestinal smooth muscle contraction by binding to specific serotonin receptors found only in the nerve cells of the GI tract and this helps restore normal bowel motility; it also helps reduce sensitivity to pain and discomfort caused by symptoms of IBS.