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Progestins

Our Progestins class of Transgender products contain various forms of the female hormone origesterone, as progestins and progestogens for use in a feminizing regime for transgender hormone therapy during a gender reassignment programme. 

Use the search feature to quickly find the product you are looking for, by entering either the active ingredient, e.g. medroxyprogesterone, or the product name, e.g. Depo Provera.

Our Progestins class of Transgender products contain various forms of the female hormone origesterone, as progestins and progestogens for use in a feminizing regime for transgender hormone therapy during a gender reassignment programme. 

Use the search feature to quickly find the product you are looking for, by entering either the active ingredient, e.g. medroxyprogesterone, or the product name, e.g. Depo Provera.
...Read more

Crinone 8% 15 Applications/Pack
Crinone 8% (Progesterone)
Progesterone Gel 8%
From $6.32 per Applications
Depo Provera 150mg/mL Disposable Syringe
Depo Provera 150mg
Medroxyprogesterone acetate
From $25.00 per mL
Duphaston 10mg 10 Tablets/Strip
Duphaston 10mg
Dydrogesterone
From $2.37 per Tablet
Endogest 100 (Progesterone 100mg) 10 Capsules/Strip
Endogest 100 (Progesterone) 100mg

Progesterone
From $0.78 per Capsule
Endogest 200 (Progesterone 200mg) 10 Capsules/Strip
Endogest 200 (Progesterone) 200mg

Progesterone
From $1.05 per Capsule
Meprate (Medroxyprogesterone acetate 10mg) 10 Tablets/Strip
Meprate (Medroxyprogesterone acetate 10mg)

Medroxyprogesterone acetate
Also known as Provera
From $0.64 per Tablet
Naturogest (Progesterone 8%) Gel (15 Prefilled Applicators/Pack) 1.35g each
Naturogest (Progesterone 8%) Gel

Progesterone
Also known as Crinone
Out Of Stock
Proluton Depot 250mg/ml (Hydroxyprogesterone) 1ml vial
Proluton Depot 250mg/ml (Hydroxyprogesterone)

Hydroxyprogesterone
Each pack includes a syringe and needle
From $8.00 per Vial
Proluton Depot 500mg/2ml (Hydroxprogesterone) 2ml vial
Proluton Depot 500mg/2ml (Hydroxyprogesterone)

Hydroxyprogesterone
Each pack includes a syringe and needle
Out Of Stock
Provera 2.5mg 30 Tablets/Pack
Provera 2.5mg
Medroxyprogesterone acetate
From $0.49 per Tablet
Provera 5mg 100 Tablets/Pack
Provera 5mg
Medroxyprogesterone acetate
From $0.51 per Tablet
Provera 10mg 30 Tablets/Pack
Provera 10mg
Medroxyprogesterone acetate
From $0.82 per Tablet
Strone-50 Injection 10 x 1ml Ampoules/Pack
Strone-50 Injection IM (Progesterone) 10 Ampoules/Pack
Progesterone
Does NOT come with syringe or needles.
From $2.53 per Ampoule
Strone-100 Injection 10 x 1ml Ampoules/Pack
Strone-100 Injection IM (Progesterone) 10 Ampoules/Pack
Progesterone
Does NOT come with syringe or needles.
From $5.64 per Ampoule
Strone-200 Injection 10 x 2ml Ampoules/Pack
Strone-200 Injection IM (Progesterone) 10 Ampoules/Pack
Progesterone
Does NOT come with syringe or needles.
From $8.90 per Ampoule
Utrogestan 100mg (Progesterone) 30 Capsules/Pack
Utrogestan 100mg (progesterone)
Progesterone
Natural micronised progesterone
From $1.09 per Capsule

What are progestins and progestogens?

Progesterone is the female hormone that in women prepares the endometrium (lining of the uterus) for a potential pregnancy.  Progestogens have the same biological activity as naturally occurring progesterone but the chemical structure has been slightly altered to improve stability and absorption. Progestins are synthetic progestogens that have a different chemical structure to progesterone but similar biological effects. 

Progestins and progestogens are used medically for contraception, hormone replacement therapy in menopausal women and to treat certain conditions like endometriosis.  

Use of progestins and progestogens for transgender hormone therapy

Although the clinical opinion is mixed on their effectiveness of use, progestins and progestogens can be used as part of the feminization regime for male to female transgender hormone therapy1.  The rational for this is that adding progesterone in some form more closely simulates the female hormone cycle.  However, there are also some side effects including, weight gain, oedema, and mood swings.  There is also an increased risk of developing breast cancer2.

Progesterone suppresses testosterone production and is also thought to support breast development in transgender hormone therapy, which is one of the roles of progesterone in females.  Although oestrogen is primarily responsible for breast development in females, progesterone is involved in regulation the growth and differentiation of breast tissue.  Also during pregnancy, progesterone contributes to increasing the size of breasts and the nipples in preparation for lactation. 

Progestin products

Progestins, which are synthetic progestogens, available are:

  • Medroxyprogesterone
  • Hydroxyprogesterone
  • Dydrogesterone
Medroxyprogesterone and hydroxyprogesterone are both administered by injection and are more potent and longer-acting than natural progesterone. Medroxyprogesterone is also available for oral administration as is dydrogesterone.  Progestins are more active when taken orally than natural progesterone and do not have other hormonal effects.

Progestogen products

Micronized progesterone, in which natural progesterone is reduced to tiny particles for better absorption, is available as a gel and as capsules.

Progesterone is also available for injection in an oil base for stability. 

References

  1. Wierckx K, Gooren L, T'Sjoen G. Clinical review: Breast development in trans women receiving cross-sex hormones. J Sex Med 2014 May;11(5):1240-7
  2. Axlund SD, Sartorius CA. Progesterone regulation of stem and progenitor cells in normal and malignant breast. Mol Cell Endocrinol 2012 Jun 24;357(1-2):71-9. 



...Read more

What are progestins and progestogens?

Progesterone is the female hormone that in women prepares the endometrium (lining of the uterus) for a potential pregnancy.  Progestogens have the same biological activity as naturally occurring progesterone but the chemical structure has been slightly altered to improve stability and absorption. Progestins are synthetic progestogens that have a different chemical structure to progesterone but similar biological effects. 

Progestins and progestogens are used medically for contraception, hormone replacement therapy in menopausal women and to treat certain conditions like endometriosis.  

Use of progestins and progestogens for transgender hormone therapy

Although the clinical opinion is mixed on their effectiveness of use, progestins and progestogens can be used as part of the feminization regime for male to female transgender hormone therapy1.  The rational for this is that adding progesterone in some form more closely simulates the female hormone cycle.  However, there are also some side effects including, weight gain, oedema, and mood swings.  There is also an increased risk of developing breast cancer2.

Progesterone suppresses testosterone production and is also thought to support breast development in transgender hormone therapy, which is one of the roles of progesterone in females.  Although oestrogen is primarily responsible for breast development in females, progesterone is involved in regulation the growth and differentiation of breast tissue.  Also during pregnancy, progesterone contributes to increasing the size of breasts and the nipples in preparation for lactation. 

Progestin products

Progestins, which are synthetic progestogens, available are:

  • Medroxyprogesterone
  • Hydroxyprogesterone
  • Dydrogesterone
Medroxyprogesterone and hydroxyprogesterone are both administered by injection and are more potent and longer-acting than natural progesterone. Medroxyprogesterone is also available for oral administration as is dydrogesterone.  Progestins are more active when taken orally than natural progesterone and do not have other hormonal effects.

Progestogen products

Micronized progesterone, in which natural progesterone is reduced to tiny particles for better absorption, is available as a gel and as capsules.

Progesterone is also available for injection in an oil base for stability. 

References

  1. Wierckx K, Gooren L, T'Sjoen G. Clinical review: Breast development in trans women receiving cross-sex hormones. J Sex Med 2014 May;11(5):1240-7
  2. Axlund SD, Sartorius CA. Progesterone regulation of stem and progenitor cells in normal and malignant breast. Mol Cell Endocrinol 2012 Jun 24;357(1-2):71-9. 



...Read more

 

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