Avigra (Sildenafil 100mg) 12's

Avigra general information

What is Avigra used for?

Avigra tablets 100mg are used to treat erectile dysfunction (impotence) in men, which is inability to achieve or maintain a hard erect penis suitable for sexual activity, due to insufficient blood flow into the penis. Avigra tablets 100mg relax the blood vessels in the penis increasing blood flow and causing an erection, which is the natural response to sexual stimulation. However, Avigra 100 will only work if you are sexually aroused.

How does Avigra work?

Avigra tablets 100mg contain sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor that acts on the erectile tissue of the penis to increase blood flow, which is needed to cause an erection. During sexual stimulation nitric oxide is released in the erectile tissue of the penis which activates the enzyme guanylate cyclase. This enzyme increases levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues to cause an erection. Another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP preventing blood flow into the penis, which causes loss of an erection. Avigra tablets 100mg inhibit the action of PDE5 which resolves erectile dysfunction by allowing the natural process of sexual stimulation to activate the cGMP mechanism for achieving and maintaining an erection.

How long does Avigra last?

Avigra tablets 100mg should be taken within an hour of planned sex and in most cases it helps you to get an erection in about 30 minutes that will last for around 4 hours, provided you are sexually excited. Avigra 100 does not work if you are not aroused.

What does Avigra contain?

Avigra tablets 100mg contain the active ingredient sildenafil which resolves erectile dysfunction (impotence) in men, by increasing blood flow into the penis. They also contain microcrystalline cellulose, calcium hydrogen phosphate anhydrous, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, glycerol triacetate, indigo carmine aluminium lake (CI 73015), and PF0102.

Treating erectile dysfunction (impotence) with Avigra

Avigra tablets 100mg contain sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor that is used to treat erectile dysfunction (impotence). When taken before planned sexual activity, Avigra 100 inhibits the breakdown (by the enzyme PDE5) of a chemical called cGMP, produced in the erectile tissue of the penis during sexual arousal, and this action allows blood flow into the penis causing an erection.

What are the side effects of Avigra?

The most commonly reported side effects when taking Avigra include: headache, dizziness, flushing, indigestion, nasal congestion, diarrhoea, rash. More serious side effects include unusual heartbeat, urinary tract infection (stinging or burning urine, more frequent need to pass urine), blood in the urine, changes in vision such as blurring, a blue colour to your vision or a greater awareness of light, persistent headache or fainting, bleeding from the nose.

When should Avigra not be used?

You should not use Avigra if you:

• are allergic to sildenafil or any other ingredients in Avigra 100mg tablets
• are taking any nitrate medication, such as nitroglycerin for angina, as it may lead to a severe drop in blood pressure
• have a condition where sexual intercourse inadvisable due to cardiovascular or heart problems or you have had a heart attack or stroke in the last 6 months
• have liver disease
• have abnormally high or low blood pressure
• have an eye disease like non-arteritic anterior ischaemic optic neuropathy (NAION), which causes loss of vision or if you have retinitis pigmentosa
• are taking medication that may interact with Avigra or may increase your risk for side-effects, including cimetidine for treating ulcers, antibiotics like erythromycin and rifampicin, verapamil or diltiazem (for high blood pressure), ritonavir or saquinavir (for HIV), the antifungals itraconazole or ketoconazole, alpha-blockers like amlodipine for high blood pressure.

What medications interact with Avigra?

Several medications interact with Avigra and should either not be taken while you are taking Avigra or only after discussion and instruction from your doctor:

• Drugs that cause a serious reaction with Avigra: any nitrate medication, such as nitroglycerin for angina
• Drugs that affect Avigra: cimetidine for treating ulcers, antibiotics like erythromycin and rifampicin, the antifungals itraconazole or ketoconazole, ritonavir or saquinavir for HIV
• Drugs that are affected by Avigra: alpha-blockers like amlodipine for high blood pressure

How should Avigra be taken?

You should take your Avigra tablet 100mg with a glass of water approximately one hour before sexual activity and without food. If you have a large meal before taking your Avigra 100mg tablet it may take longer to work. You should take no more than one tablet a day and only if you plan to have sex.

Missed dose of Avigra

You should only take an Avigra 100mg tablet when you plan to have sex; it is not intended as a regular medication.

How should Avigra be stored?

You should store your Avigra below 25°C in a cool dry place.