United States / USD Country & Currency
Country
United States
Currency
US Dollars
Save
Country
Australia
Gibraltar
Hong Kong
Malta
Northern Ireland
Puerto Rico
Scotland
Singapore
Switzerland
United Kingdom
United States
Currency
US Dollars
GB Pounds
AU Dollars
Euro
Explore our range Categories
Ask us a question 877-271-6591 or 800-868-9064
ATTENTION: US CUSTOMERS

Please be advised that there are currently significant Customs Processing Delays at JFK, NY and Newark, NJ ports of entry.

Please understand that these delays are outside our control—We sincerely apologise for any inconvenience encountered. Please consider ordering in advance to allow for longer than usual delays.

Shipping delays due to Covid-19 Virus

Please fill the form to receive updates when we can ship your order.

Trustiva 30 Tablets / pack (Tenofovir Disoproxil Fumarate 300mg/Emtricitabine 200mg/Efavirenz 600mg)

Spacer Image
Trustiva 30 Tablets / pack (Tenofovir Disoproxil Fumarate 300mg/Emtricitabine 200mg/Efavirenz 600mg)

Trustiva 30 Tablets / pack


Product Name
Trustiva 30 Tablets / pack (Tenofovir Disoproxil Fumarate 300mg/Emtricitabine 200mg/Efavirenz 600mg)
Active Ingredient
Tenofovir Disoproxil Fumarate 300mg/Emtricitabine 200mg/Efavirenz 600mg
Manufacturer
Product Type
Antiretroviral (HIV)
Product expiry date we are currently shipping
Jun 2026
Trustiva tablets contain efavirenz, emtricitabine and tenofovir, which are antiretroviral drugs used to treat HIV infection, to prevent or slow down the spread of infection.
Product Price List
REMEMBER SHIPPING IS FREE!

Trustiva 30 Tablets / Pack
$5.00 per Tablet
|
$150.00 (USD)
$150.00 (USD)
Trustiva 60 Tablets / Pack
$4.67 per Tablet
|
$280.00 (USD)
$280.00 (USD)
Trustiva 90 Tablets / Pack
$4.33 per Tablet
|
$390.00 (USD)
$390.00 (USD)
Trustiva 180 Tablets / Pack
$4.00 per Tablet
|
$720.00 (USD)
$720.00 (USD)

Trustiva general information

What is Trustiva used for?

Trustiva tablets are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over age 18. Trustiva tablets are used to treat HIV patients who have already received treatment with other HIV medications and have responded to all medications prescribed; they can also be used alone as monotherapy or in combination with other HIV medications. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection, which can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Trustiva tablets prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4 cell numbers, so that the immune system can recover, reducing the risk of disease progression.

How does Trustiva work?

Trustiva tablets contain a combination of three antiretroviral drugs, efavirenz, emtricitabine and tenofovir disoproxil fumarate, which are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). These three drugs each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) and acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides, which are the precursors to the building blocks of DNA and RNA. Tenofovir and Emtricitabine are both nucleoside analogue reverse transcriptase inhibitors (NRTI), which means that they block the action of RT by competing with one of the nucleosides needed to transcribe the viral RNA into DNA, becoming incorporated into the chain of newly synthesized viral DNA and preventing it from growing (chain termination). Emtricitabine is an analogue of cytidine and tenofovir is an analogue of adenosine. The combined action of the three antiiretroviral drugs in Trustiva tablets prevents the integration of the virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus). Trustiva tablets slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

What does Trustiva contain?

Trustiva tablets contain three active ingredients, the antiretrovirals efavirenz (600mg), tenofovir disoproxil fumarate (300mg) and emtricitabine (200mg), used to treat HIV infection.

Treating HIV infection with Trustiva

Trustiva tablets contain a combination of three antiretroviral drugs, efavirenz, emtricitabine and tenofovir, which are only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection, which can lead to opportunistic life-threatening infection (infections that would not normally be harmful), including pneumonia, herpes virus infections, and Mycobacterium avium complex (MAC) infection. If too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). The three antiretroviral drugs in Trustiva tablets each work by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT) which is needed for the virus to be able to replicate, as it converts viral RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Trustiva tablets prevent the integration of HIV into the DNA of the infected CD4+ cell, which inhibits the replication of HIV so that no more virus can be produced and this reduces the viral load (amount of virus). Trustiva tablets slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others.

What are the side effects of Trustiva?

The most commonly reported side effects when taking Trustiva tablets include: headache, gastrointestinal upset (nausea, diarrhoea, constipation, stomach pain), anorexia, dizziness, fatigue, rash, hot flush, difficulty sleeping, nightmare, depression, depressed mood, anxiety, insomnia, altered mood, abnormal dreams. A more serious but less common side effect is a condition called lactic acidosis which is excess lactic acid in the blood due to liver damage, which may cause pancreatitis, liver failure, or renal failure.

What are the health risks when taking Trustiva?

Lactic acidosis is a rare but potentially fatal condition that has been reported when taking Trustiva tablets. It is caused by a build up of excess of lactic acid in the blood due to liver damage, which is usually associated with hepatomegaly (liver enlargement) with steatosis (build up of fat in the liver) and may cause pancreatitis, liver failure, or renal failure. Symptoms begin within a few months of treatment and include: nausea, vomiting and abdominal pain, difficulty breathing, loss of appetite, weight loss, motor weakness.

When should Trustiva not be used?

You should not use Trustiva tablets if you:


  • are allergic to efavirenz, emtricitabine and tenofovir or any ingredients in Trustiva
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • have hepatitis B infection
  • have a mental illness, including depression; convulsions; or bone disease like osteoporosis without discussion with your doctor, as your condition may worsen
  • are taking medicines that interact with Trustiva, including: cisapride for reflux, midazolam and triazolam for sedation and anxiety, the antipsychotic pimozide, bepridil for angina, Cafergot for migraine, the antifungal voriconazole and Itraconazole, other medications containing efavirenz, emtricitabine, or tenofovir, other retrovirals like ritonavir or lamivudine, herbal preparations containing St. John's wort, the anticonvulsant phenobarbital, antibiotics like clarithromycin rifampicin, statins like simvastatin for lowering cholesterol, the anticoagulant warfarin, the anticonvulsants carbamazepine and Phenytoin, the antidepressant sertraline, the calcium channel blocker diltiazem for high blood pressure, oral contraceptives


What medications interact with Trustiva?

Several medications interact with Trustiva and should either not be taken while you are taking Trustiva or only after discussion and instruction from your doctor:


  • Drugs that cause a serious reaction with Trustiva: cisapride for reflux, midazolam and triazolam for sedation and anxiety, the antipsychotic pimozide, bepridil for angina, Cafergot for migraine, herbal preparations containing St. John's wort, the retroviral lamivudine
  • Drugs that affect Trustiva: the anticonvulsant phenobarbital, the antiinfective rifampin, other retrovirals like ritonavir
  • Drugs that are affected by Trustiva: the antifungals voriconazole and Itraconazole, statins like simvastatin for lowering cholesterol, the anticoagulant warfarin, the anticonvulsant carbamazepine and Phenytoin, the antidepressant sertraline, the calcium channel blocker diltiazem for high blood pressure, antibiotics like clarithromycin rifampicin, oral contraceptives


How should Trustiva be taken?

You should take your Trustiva tablets with a glass of water once a day on an empty stomach (1 hour before or 2 hours after a meal), preferably at bedtime, to reduce problems with side effects. You should continue to take your Trustiva tablets regularly for as long as your doctor recommends, and you condition should be monitored. Do not suddenly stop taking your Trustiva tablets as this may increase risk of HIV resistance.


How long should you take Trustiva?

You should continue to take your Trustiva tablets regularly for as long as your doctor recommends, and you condition should be monitored.


Missed dose of Trustiva

If you miss a dose of Trustiva tablets take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.


How should Trustiva be stored?

You should store your Trustiva below 25°C in a cool dry place.







See more products in
 

This website uses cookies. View our policy and select your preferences here