Lifanta Eye Drops 0.05% (Lifitegrast) 3ml/Pack

General information

What is Lifanta used for?

Lifanta Opthalmic solution 5% is an eye drop solution that is used twice daily in each eye to treat the signs and symptoms of dry eye disease (DED) in adults over the age of 17 years.

How does Lifanta work?

Lifanta Opthalmic solution 5% is an eye drop solution that is used twice daily in each eye to treat the signs and symptoms of dry eye disease (DED) in adults over the age of 17 years.

Lifanta Opthalmic solution 5%   works by preventing a certain protein called lymphocyte function-associated antigen-1 (LFA-1) on the surface of leukocytes (a type of blood cell), from binding to a type of adhesion molecule called ICAM-1 which may be overexpressed in corneal and conjunctival tissues in people with DED. The interaction between LFA-1 and ICAM-1 is associated with T-cell activation and migration and the secretion of inflammatory cytokines. By blocking this interaction, Lifanta Opthalmic solution 5%   may prevent the secretion of inflammatory cytokines which improves the symptoms of DED, although the exact way it works in DED is not known.

What does Lifanta contain?

Active ingredients: lifitegrast 5% (50 mg/mL).

This is the therapeutic component that reduces inflammation on the eye surface in dry eye disease.

Inactive ingredients: sodium chloride, sodium phosphate dibasic anhydrous, sodium thiosulfate pentahydrate, sodium hydroxide, and/or hydrochloric acid (to adjust pH) and water for injection.

The inactive ingredients help stabilize the solution, maintain pH, and make it safe for the eye.

Treating dry eyes with Lifanta

Lifanta Opthalmic solution 5%  is specifically designed for treating dry eye disease (DED).

In dry eye, inflammation on the eye surface damages the tear film and causes stinging, burning and irritation.

Lifitegrast (the active ingredient) is an LFA-1 antagonist and it blocks interaction between LFA-1 (on T cells) and ICAM-1 (on eye surface cells).

This reduces T-cell mediated inflammation, leading to less irritation and redness and protection of the ocular surface with improved tear film stability.

What are the side effects of Lifanta?

Common side effects of Lifanta Opthalmic solution 5%  may include blurred vision, eye discomfort, eye irritation, or an unusual or unpleasant taste in the mouth.

Get emergency medical help if you have signs of an allergic reaction to Lifanta Opthalmic solution 5% , such as hives, difficulty breathing, or swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• vision problems
• severe eye redness or irritation.

When should Lifanta not be used?

Before you use Lifanta Opthalmic solution 5%  , tell your doctor if you:

• are using any other eye drops
• wear contact lenses
• are pregnant or plan to become pregnant. It is not known if Lifanta Opthalmic solution 5%  will harm your unborn baby
• are breastfeeding or plan to breastfeed. It is not known if Lifanta Opthalmic solution 5% passes into your breast milk. Talk to your doctor about the best way to feed your baby if you use Lifanta Opthalmic solution 5%.

Lifanta Opthalmic solution 5% is not approved for use by anyone younger than 17 years old.

There are no contraindications to the use of Lifanta Opthalmic solution 5%.  

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

How should Lifanta be used?

Wash your hands before using the eye drops.

• Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop.
• Instil one drop of into each eye twice daily (approximately 12 hours apart).
• Wait at least 10 minutes before using any other eye drops your doctor has prescribed.

Do not touch the tip of the Lifanta Opthalmic solution 5% eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems.

Each container of Lifanta Opthalmic solution 5%   is for single use only. Throw away the container after putting the drops in each eye, even if some solution remains.

If you wear contact lenses, remove them before putting Lifanta Opthalmic solution 5%   into your eyes. You can reinsert them 15 minutes later.

Use Lifanta Opthalmic solution 5%   exactly as directed by your healthcare provider. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

How long should you take Lifanta?

Lifanta Opthalmic solution 5% is generally used as a long-term treatment for dry eye disease, not just a short course of treatment.

It often takes 4-12 weeks of consistent use before people notice meaningful improvements in symptoms.

Continued treatment is usually recommended as long as the benefits outweigh side effects, because dry eye disease is a chronic condition.

Some people stay on it for many months to years under medical supervision, and always follow your Health Professional’s advice.

Missed dose of Lifanta

Instil the missed dose of Lifanta Opthalmic solution 5%  as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up for the missed dose.

How should Lifanta be stored?

Store Lifanta Opthalmic solution 5% at room temperature 20-25°C  away from moisture, heat, and light.

Keep out of the reach of children.