Soltop-S 3% Lotion (Clobetasol & Salicylic Acid)

Soltop-S Lotion general information

What is Soltop-S Lotion used for?

Soltop-S Lotion is used to treat dry resistant hyperkeratotic skin conditions of the skin and scalp, in which the outer layer of the skin becomes thickened, dry and scaly.  These conditions include, recalcitrant eczema (difficult to treat), dermatitis, lichen planus (itchy swollen rash on the skin, mouth or tongue) and Ichthyosis vulgaris (accumulation of dry dead skin in patches that look like fish scales), seborrhoeic dermatitis (a scaly rash that usually affects areas of the skin or scalp that are greasy or oily) and moderate to severe plaque psoriasis (thickening of the skin).  Psoriasis is a non-allergic chronic inflammatory skin disease that is characterised by the appearance of red raised patches of thickened skin covered in a dry silvery scaly rash usually on the skin of the elbows, knees and lower back.  Psoriasis is thought to be an autoimmune disorder (hyperactivity of the immune system which then attacks self) with a genetic predisposition.  Soltop-S Lotion helps relieve symptoms of psoriasis and other hyperkeratotic conditions such as itching, redness, dryness, crusting and scaling; also helps reduce thickening of the skin. 

How does Soltop-S Lotion work?

Soltop-S Lotion contains the synthetic corticosteroid clobetasol 0.05%, which is a high potency anti-inflammatory that is more potent than hydrocortisone.  Clobetasol in Soltop- S  Lotion works by blocking the production of inflammatory chemicals, like prostaglandins and leukotrienes, which are hormone-like substances involved in the inflammatory process.  Clobetasol in Soltop- S Lotion also narrows and constricts causes blood vessels that have become dilated (widened) and leaky allowing other inflammatory cells into the skin to escalate the inflammatory response.  This reduces symptoms of inflammatory skin conditions particularly those that do not respond satisfactorily to less active steroids.  Soltop-S Lotion also contains salicylic acid (3%), a keratolytic that works by softening keratin, which is a fibrous structural protein found in the upper layer of the skin.  Softening the keratin helps loosen the dry scaly skin and allows the corticosteroid component of Soltop-S Lotion to penetrate the skin more easily, which enhances the anti-inflammatory effect of  of Soltop-S Lotion and its effectiveness in relieving symptoms of psoriasis and other hyperkeratotic conditions.  

What does Soltop-S Lotion contain?

Soltop-S Lotion contains the active ingredients clobetasol proprionate 0.05%, a corticosteroid anti-inflammatory and salicylic acid 3%, a keratolytic, used in combination to treat dry resistant hyperkeratotic skin conditions. It also contains an aqueous base.

Treating dry hyperkeratotic skin conditions with Soltop-S Lotion

Soltop-S Lotion contains a combination of active ingredients that are used to treat a variety of moderate to severe dry resistant hyperkeratotic skin conditions of the skin and scalp, in which the outer layer of the skin becomes thickened, dry and scaly.  These conditions include recalcitrant eczema (difficult to treat), dermatitis, lichen planus (itchy swollen rash on the skin, mouth or tongue) and Ichthyosis vulgaris (accumulation of dry dead skin in patches that look like fish scales), seborrhoeic dermatitis (a scaly rash that usually affects areas of the skin or scalp that are greasy or oily) and moderate to severe plaque psoriasis (thickening of the skin).  Psoriasis is a non-allergic chronic inflammatory skin disease that is characterised by the appearance of red raised patches of thickened skin covered in a dry silvery scaly rash usually on the skin of the elbows, knees and lower back.  Psoriasis is thought to be an autoimmune disorder (hyperactivity of the immune system which then attacks self) with a genetic predisposition.  Clobetasol in Soltop- S Lotion is a synthetic corticosteroid and a highly potent anti-inflammatory that works by blocking the production of inflammatory chemicals, like prostaglandins and leukotrienes, which are hormone-like substances involved in the inflammatory process.  Clobetasol in Soltop- S Lotion also narrows and constricts causes blood vessels that have become dilated (widened) and leaky allowing other inflammatory cells into the skin to escalate the inflammatory response.  This reduces symptoms of inflammatory skin conditions particularly those that do not respond satisfactorily to less active steroids.  Salicylic acid in Soltop-S Lotion is a keratolytic that works by softening keratin, a fibrous structural protein found in the upper layer of the skin, which loosens dry scaly skin and allows the clobetasol to penetrate the skin more easily and improve its effectiveness.  Soltop-S Lotion relieves symptoms of inflammation; as well as reducing dryness, scaling and thickening of the skin

What are the side effects of Soltop-S Lotion?

The most commonly reported side effects when taking Soltop-S Lotion include burning, itching, irritation, cracking, fissuring and dryness at the site of application, also long-term use can cause hypopigmentation (loss of skin pigment), and skin atrophy.  Long-term use of Soltop -S Lotion may cause the adrenal glands, which produce endogenous (naturally occurring) corticosteroids, to stop working efficiently and this may slow down the growth rate in children.

When should Soltop-S Lotion not be used?

You should not use Soltop-S Lotion if you:

• are allergic to clobetasol, salicylic acid, lactic acid, urea or any ingredients in Soltop -S Lotion
• are pregnant or are breastfeeding
• have a viral infection of the skin, tuberculosis, acne rosacea (a chronic skin condition), perioral dermatitis (facial rash around the mouth), fungal skin infections and ulcerative conditions
• have damaged skin

How should Soltop-S Lotion be used?

You should apply a thin film of Soltop-S Lotion to the affected area of skin two or three times daily by gently rubbing into the skin.  You should always wash your hands after applying the medication and make sure you don’t get any in your eyes, nose or mouth.  Soltop-S Lotion is intended for short term use and should not be used for more than 2 weeks.  If there is no improvement in symptoms within 2 weeks, you should follow you doctors recommendations.

How long should you use Soltop-S Lotion?

Soltop-S Lotion is intended for short term use and should not be used for more than 2 weeks.  If there is no improvement in symptoms within 2 weeks, you should follow you doctors recommendations.

Missed dose of Soltop-S Lotion

If you miss a dose of Soltop-S Lotion apply it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Soltop-S Lotion be stored?

You should store your Soltop-S Lotion below 25°C in a cool dry place.