Breo Ellipta 200/25 (fluticasone, vilanterol)
Breo Ellipta 200/25 (fluticasone, vilanterol) 30 Doses/Pack
Powder for Inhalation, pre dispensed
Fluticasone Furoate 200mcg, Vilanterol 25mcg
Corticosteroid anti-inflammatory Bronchodilator (beta-agonist)
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Breo Ellipta general information
What is Breo Ellipta used for?
Breo Ellipta inhaler 200/25 is a combination medication used for the regular long-term treatment and management of asthma, a reversible obstructive airways disease, where a combination medication is considered appropriate. This includes, patients already using a combination medication, or using an inhaled preventer medication but are not adequately controlled and are still having symptoms, or patients using a reliever medication as needed, to treat symptoms of asthma, but are not adequately controlled. Breo Ellipta Inhaler should not be used for severe asthma or as a “reliever” for asthma attack. The combination of medications in Breo Ellipta 200/25 Inhaler work together to provide better control of asthma to protect against symptoms like tightness of the chest, wheezing and shortness of breath; also to prevent exacerbations of asthma and improve lung function.
How does Breo Ellipta work?
Breo Ellipta inhaler 200/25 contains a combination of two medications that work by different mechanisms of action to control and manage asthma, a reversible obstructive airways disease. Fluticasone in Breo Ellipta inhaler 200/25 is a corticosteroid that blocks Inflammation, one of the underlying causes of asthma. This is a preventer medication and works by inhibiting the production of inflammatory chemicals like cytokines, released by several immune cell types, including macrophages and lymphocytes, in the airways in response to asthma trigger, such as allergens or irritants in the air. Inhibition of these cytokine reduces inflammation and swelling of the airways. Vilanterol in Breo Ellipta inhaler is a long-acting beta2-agonist and bronchodilator that relaxes the muscles of the small airways of the lungs (bronchioles) to widen the airways. This reduces bronchospasm (constriction or the airways) relieving symptoms of asthma such as tightness of the chest, wheezing and shortness of breath. Fluticasone and Vilanterol in Breo Ellipta inhaler 200/25 work synergistically together to enhance the anti inflammatory activity of Breo Ellipta inhaler, providing relief for up to 24 hours. They are delivered as a dry inhalation powder directly into the bronchioles of the lung and work together to improve lung function, and to reduce symptoms and exacerbations of asthma.
What does Breo Ellipta contain?
Breo Ellipta inhaler contains the active ingredients fluticasone furoate (200mcg) a corticosteroid and vilanterol trifenatate a long-acting bronchodilator (25mcg), used in combination to treat asthma. Each blister also contains 12.5 milligram lactose monohydrate per blister and magnesium stearate. Breo Ellipta inhaler comprises a plastic inhaler with two double foil blister strips, containing the active ingredients as an inhalation powder, with one strip containing fluticasone and the other strip containing vilanterol. Each foil strip contains 30 blisters for 30 doses, providing a single dose with each actuation (puff).
Should you use Breo Ellipta with other asthma inhalers?
Breo Ellipta inhaler 200/25 is used as a long-term “preventer” medication to reduce inflammation and swelling of the airways of the lung, and reduce bronchospasm (constriction or narrowing of the bronchioles or small airways) as part of an asthma management plan to reduce symptoms and exacerbations of asthma, and to improve lung function. You may also be prescribed a short-acting bronchodilator for relief of bronchospasm during an asthma attack, to be used as needed. Both are intended to be taken together, only if recommended by your doctor.
Treating asthma with Breo Ellipta
Breo Ellipta inhaler 200/25 contains a combination of fluticasone, a corticosteroid that blocks Inflammation, one of the underlying causes of asthma; and vilanterol, a long-acting bronchodilator that relieves bronchospasm (constriction or narrowing of the bronchioles or small airways) and widens the airways to allow air to flow more easily into the lungs. Breo Ellipta inhaler 25/200 is used as an asthma prevention medication to improve lung function, and to reduce exacerbations of asthma and symptoms like tightness of the chest, wheezing and shortness of breath. Fluticasone and Vilanterol in Breo Ellipta inhaler work synergistically together to enhance the anti inflammatory activity of Breo Ellipta inhaler, providing relief for up to 24 hours. Breo Ellipta inhaler should not be used as a “reliever” or “rescue” medication for an asthma attack.
What are the side effects of Breo Ellipta?
The most commonly reported side effects when taking Breo Ellipta include fungal infection in the mouth or throat or tongue (candidiasis or thrush), persistent soreness in the mouth or throat, distorted voice, weakened immune system and increased chance of getting infections like pneumonia and bronchitis, upper respiratory tract infection like sinusitis, pharyngitis. rhinitis, influenza; headache, tachycardia (rapid heartbeat), tremor (shaky or tense feeling), palpitations, muscle cramps, abdominal pain, joint pain (arthralgia), back pain, fractures, fever.
What are the health risks of Breo Ellipta?
Long term use of Breo Ellipta may cause the adrenal glands, which produce endogenous (naturally occurring) corticosteroids, to stop working efficiently, which may slow down the growth rate in children and adolescents and will need regular monitoring. This may also cause decreased bone mineral density if used for long periods.
What is paradoxical bronchospasm?
All inhaled asthma medications can cause paradoxical bronchospasm, which is when the inhaled medication taken to relieve or prevent bronchospasm actually makes it worse, causing wheezing, shortness of breath and tightness of the chest. If this happens you should inform your doctor and take their advice.
When should Breo Ellipta not be used?
You should not use Breo Ellipta inhaler 200/25 if you:
- are allergic to fluticasone or vilanterol or milk proteins or any ingredients in Breo Ellipta
- are pregnant or are breastfeeding, without discussion with your doctor
- have chronic obstructive pulmonary disorder (COPD) an this dose of Breo Ellipta inhaler is not indicated for COPD, only the lower dose of 100/25
- have liver disease
- have osteoporosis, without discussion with your doctor
- have tuberculosis of the lung or other long term lung infection
- have severe have cardiovascular disease
- are taking medicines that interact with Breo Ellipta, like ritonavir for HIV infection, ketoconazole for fungal infection, or a beta-blocker like propranolol
How should Breo Ellipta be taken?
You should use your Breo Ellipta by taking one puff once daily morning or evening but at the same time each day, as recommended by your doctor. You should begin to feel relief of symptoms within 15 minutes of inhalation but Breo Ellipta inhaler is intended as a long-term medication to maintain control of symptoms. You should continue to take your Breo Ellipta inhaler 25/200 as long as recommended by your doctor and you should not stop taking your Breo Ellipta inhaler even if you feel better.
How to use your Breo Ellipta inhaler
Follow the instructions provided for using your Breo Ellipta inhaler.
- Open the cover of your Breo Ellipta inhaler until it clicks to release a dose of medication.
- Breathe out as far as is comfortable and then place the mouthpiece in your mouth and inhale through your mouth until your lungs are full.
- Hold your breath for a few seconds, and then breathe normally. The dose counter will indicate how many doses you have left in you inhaler.
- Close the cover.
- Rinse your mouth after use.
How long should you take Breo Ellipta?
You should continue to take your Breo Ellipta 200/25 Inhaler as long as recommended by your doctor and you should not stop taking your Breo Ellipta inhaler even if you feel better.
Missed dose of Breo Ellipta
If you miss a dose of Breo Ellipta take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Breo Ellipta be stored?
You should store your Breo Ellipta below 25°C in a cool dry place.