Cefybond 250 (Cefuroxime) 250mg

Cefybond general information

What is Cefybond used for?

Cefybond tablets 250mg are a broad spectrum antibiotic used to treat common infections caused by a variety of bacteria in different parts of the body.  These include upper respiratory tract infections, such as ear infections (otitis media), sinusitis, tonsillitis and pharyngitis; also lower respiratory tract infections such as pneumonia and acute bronchitis, including acute exacerbations of chronic bronchitis.  Cefybond 250 is also used for genitourinary tract infections like, cystitis and pyelonephritis (kidney infection); skin and soft tissue infections such as, furunculosis (infection of the hair follicle), pyoderma (pus filled skin infection) and impetigo (a blistering sore skin infection).  Cefybond tablets 250mg are also used to treat genital infections including gonorrhoea, acute uncomplicated gonococcal urethritis, and cervicitis. 

How does Cefybond work?

Cefybond tablets 250mg contain cefuroxime, a second generation cephalosporin antibiotic, belonging to a sub group of the beta lactam group of antibiotics (which include penicillins).  Cefuroxime in Cefybond 250 is a prodrug that is hydrolysed to its active form.  The active form of cefuroxime then attaches to the penicillin binding proteins on the bacterial cell wall. This inhibits the synthesis of the peptidoglycan layer of the bacterial cell wall, which is important for the structural integrity of the cell wall.  Blocking formation of the bacterial cell wall in susceptible bacteria kills the bacteria.  Unlike other beta lactam antibiotics like penicillins, cephalosporins are less susceptible to destruction by beta-lactamase found in some resistant bacteria.  Cefuroxime has good stability to bacterial beta-lactamase and is therefore, active against many ampicillin-resistant or amoxycillin-resistant strains.  Cefuroxime in Cefybond 250 is effective against a wide range of common bacteria found in general practice and in hospitals including: Streptococcus pyogenes, Staphylococcus aureus (including penicillinase-producing strains and non-resistant strains); Haemophilus influenzae; Klebsiella pneumonia, Escherichia coli among others.  

What does Cefybond contain?

Cefybond tablets 250mg contains the active ingredient contain the active ingredient cefuroxime axetil, a cephalosporin antibiotic belonging to a sub group of the beta lactam group of antibiotics, which is used to treat a wide range of bacterial infections. 

Treating bacterial infection with Cefybond

Cefybond tablets 250mg contain cefuroxime, abroad spectrum antibiotic used to treat common infections caused by a variety of bacteria in different parts of the body.  These susceptible bacteria include Streptococcus pyogenes, Staphylococcus aureus (including penicillinase-producing strains and non-resistant strains); Haemophilus influenzae; Klebsiella pneumonia, Escherichia coli among others.  Cefuroxime in Cefybond tablets 250mg is used to treat upper respiratory tract infections, such as ear infections (otitis media), sinusitis, tonsillitis and pharyngitis; also lower respiratory tract infections such as, pneumonia and acute bronchitis, including acute exacerbations of chronic bronchitis.  Cefybond 250 is also used for genitourinary tract infections like, cystitis and pyelonephritis (kidney infection); skin and soft tissue infections such as, furunculosis (infection of the hair follicle), pyoderma (pus filled skin infection) and impetigo (a blistering sore skin infection).  Cefybond 250 is also used to treat genital infections including gonorrhoea, acute uncomplicated gonococcal urethritis, and cervicitis.  Cefuroxime in Cefybond tablets 250mg work by blocking formation of the bacterial cell wall in susceptible bacteria, which kills the bacteria.  Cefuroxime in Cefybond 250 is less susceptible than some penicillin like antibiotics to destruction by beta-lactamase found in some resistant bacteria and can therefore, be used against resistant bacterial strains. 

What are the side effects of Cefybond?

The most commonly reported side effects when taking Cefybond 250 include: gastrointestinal upset, diarrhoea, nausea, vomiting, stomach pain, skin rash, genital and anal pruritis (itching), due to candida overgrowth, headache, dizziness.

When should Cefybond not be used?

You should not use Cefybond tablets 250mg if you:

• are allergic to cefuroxime or any other beta-lactam antibiotic, including penicillins or any ingredients in Cefybond
• are pregnant or are breastfeeding, without discussion with your doctor
• have kidney disease without discussion with your doctor
• have a history of gastrointestinal disease particularly pseudomembranous colitis
• are taking medicines that interact with Cefybond, including probenecid for gout, oral contraceptives, anticoagulants like warfarin, medications to reduce gastric acidity may lower bioavailability of cefuroxime

What medications interact with Cefybond?

Several medications interact with Cefybond 250 and should either not be taken while you are taking Cefybond or only after discussion and instruction from your doctor:

• Drugs that cause a serious reaction with Cefybond: probenecid for gout
• Drugs that affect Cefybond: medications to reduce gastric acidity may lower bioavailability of cefuroxime
• Drugs that are affected by Cefybond: oral contraceptives, anticoagulants like warfarin

How should Cefybond be taken?

You should take your Cefybond tablets 250mg swallowed whole with a glass of water, and after food.  The dose you take and how often, depends on what you are being treated for and your doctor’s recommendation, which is usually twice daily for an average of 7 days, but may be 5-10 days, depending on your condition.  You should continue to take your Cefybond 250 for as long as recommended by your doctor and always finish your course of tablets even if you feel better, if not, the infection may not clear up completely or your symptoms may return.

How long should you take Cefybond?

You should continue to take your Cefybond tablets 250mg  for as long as recommended by your doctor and always finish your course of tablets even if you feel better, if not, the infection may not clear up completely or your symptoms may return.

Missed dose of Cefybond

If you miss a dose of Cefybond 250 take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Cefybond be stored?

You should store your Cefybond tablets 250mg below 25°C in a cool dry place.