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Eliquis (Apixaban 5mg) 60 Tablets/Pack (Turkish)


Eliquis (Apixaban 5mg) 60 Tablets/Pack (Turkish)

Eliquis (Apixaban) 5mg (Sourced from Turkey)


Product Name
Eliquis (Apixaban 5mg) 60 Tablets/Pack (Turkish)
Tablets CANNOT be split - must be taken whole. Original branded product (Turkish writing) - comes with English language leaflet.
Active Ingredient
Apixaban
Manufacturer
Pfizer
Product Type
Oral anticoagulant
Product expiry date we are currently shipping
Jan 2022
Packaging & Product
IMPORTANT: Eliquis made by BMS is sourced from Turkey. The packaging has Turkish writing on it but in all other respects is the same product. We supply an English Language leaflet for all Turkish products. Please do not order if this is unsuitable for your requirements.

Eliquis tablets 5mg contain apixaban, a fast acting and highly specific anticoagulant that is used to treat and prevent the formation of blood clots (thrombosis) in conditions where an embolism may result and could be life threatening. 

Product Price List
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Eliquis (Apixaban) 5mg [Turkish] 60 Tablets
$3.02 per Tablet
|
$181.00 (USD) 
$181.00 (USD) 
Eliquis (Apixaban) 5mg [Turkish] 120 Tablets
$2.41 per Tablet
|
$289.00 (USD) 
$289.00 (USD) 
Eliquis (Apixaban) 5mg [Turkish] 180 Tablets
$2.15 per Tablet
|
$387.00 (USD) 
$387.00 (USD) 
Other Strengths


Eliquis general information

What is Eliquis used for?

Eliquis tablets 5mg are used to treat and prevent the formation of blood clots (thrombosis) in conditions where an embolism may result and could be life threatening.  Blood clot formation is a normal response to blood vessel damage to stop bleeding.  However, a blood clot (thrombus) can also form in situations where blood flow is disturbed or slows down due to reduced mobility, heart failure or atrial fibrillation (irregular heart beat).  If a clot becomes detached from the vessel it can travel through the circulation and this is a thromboembolism.  Blood clot formation in the veins is called a venous thrombosis or deep vein thrombosis, because they usually occur in the deep veins of the leg or pelvis and can become lodged in the lungs causing a pulmonary embolism.  If a clot forms in an artery or in the heart, it can block the blood supply to the heart tissue and cause a myocardial infarction (heart attack); or it can travel to the brain and cause a stroke.  Eliquis tablets 5mg are used to prevent venous thromboembolism (VTE) following hip or knee replacement surgery when there is increased risk of blots clots due to immobility; also to treat and prevent recurrent deep vein thrombosis (DVT) and pulmonary embolism (PE).  Eliquis tablets 5mg are used to prevent stroke and systemic embolism (blood clots in peripheral blood vessels) due to non-valvular atrial fibrillation and other risk factors, such as congestive heart failure, hypertension (high blood pressure), increasing age over 75 years, diabetes mellitus, prior stroke or transient ischaemic attack (mini stroke).  Eliquis tablets 5mg are also used for treatment of DVT and PE, and prevention of recurrent DVT and PE.

How does Eliquis work?

Eliquis tablets 5mg contain apixaban, which is a reversible, direct and highly selective inhibitor of Factor Xa, a clotting factor in the coagulation cascade.  Factor Xa is a serine protease, an enzyme that converts prothrombin to its active form thrombin.  The coagulation cascade involves the interaction of a series of coagulation factors, which are mostly enzymes, resulting in the generation of a plug formed by a fibrous protein (fibrin) that combines with a clump of aggregated platelets and becomes a blood clot or thrombus.  This cascade is activated to prevent bleeding under normal conditions, following injury or trauma to a blood vessel.  It can also be activated if blood becomes stagnant and is no longer free flowing such as when muscles are paralysed during surgical anaesthesia or if the heart pumping mechanism fails such as due to atrial fibrillation.  The intrinsic pathway is initiated when collagen is exposed in damaged blood vessel walls and the extrinsic pathway is activated by tissue factor released from blood vessels as a result of trauma to the endothelial cell lining of the blood vessel.  The activation of Factor Xa is the common link in the coagulation cascade.  Factor Xa plays a pivotal role in the coagulation pathway by directly converting prothrombin to thrombin, which leads to the generation of fibrin resulting in clot formation.  The activation of factor Xa causes amplification of coagulation with a burst of thrombin generation.  Therefore, inhibition of Factor Xa is an effective target for preventing thrombosis, by rapidly inhibiting the burst of fibrin generation and thereby preventing formation of a clot from both the intrinsic and extrinsic pathway.  Several of the coagulation factors, are dependent on Vitamin K as a cofactor in their production and include factors VII, IX, X and II; these are the target of other anticoagulants like warfarin, which can take time to become effective and may need dose adjustment.  Apixaban in Eliquis tablets 20mg is fast acting with maximum effect within 3 to 4 hours with high bioavailability when taken orally, is not affected by dietary vitamin K and is effective at a fixed dose.  Apixaban in Eliquis tablets 5mg has no direct effects on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin.  By inhibiting Factor Xa, apixaban prevents thrombin generation and thrombus development at doses that that does not interfere with haemostasis, which is the normal control of bleeding.  

What does Eliquis contain?

Eliquis tablets contain the active ingredient apixaban 5mg, an inhibitor of coagulation Factor Xa, used to treat and prevent the formation of blood clots (thrombosis).  They also contain anhydrous lactose, microcrystalline cellulose (E460), croscarmellose sodium, sodium laurilsulfate, magnesium stearate (E470b), lactose monohydrate, hypromellose (E464), titanium dioxide (E171), triacetin (E1518, yellow iron oxide (E172)

Treating thrombosis with Eliquis

Eliquis tablets 5mg contain apixaban, an anticoagulant are used to treat and prevent the formation of blood clots (thrombosis) in conditions where blood flow is disturbed or slows down due to reduced mobility, heart failure and atrial fibrillation (irregular heart beat).  If a clot (thrombus) becomes detached from the vessel it can travel through the circulation and this is a thromboembolism, which could be life threatening if it blocks the blood supply to the heart tissue causing a myocardial infarction (heart attack), or the brain causing a stroke.  Blood clot formation in the veins is called a venous thrombosis or deep vein thrombosis, because they usually occur in the deep veins of the leg or pelvis and can become lodged in the lungs causing a pulmonary embolism.  Eliquis tablets 5mg are used to prevent venous thromboembolism (VTE) following hip or knee replacement surgery when there is increased risk of blots clots due to immobility; also to treat and prevent recurrent deep vein thrombosis (DVT) and pulmonary embolism (PE).  Eliquis tablets 20mg are used to prevent stroke and systemic embolism (blood clots in peripheral blood vessels) due to non-valvular atrial fibrillation and other risk factors, such as congestive heart failure, hypertension (high blood pressure), increasing age over 75 years, diabetes mellitus, prior stroke or transient ischaemic attack (mini stroke).  Apixaban in Eliquis tablets 5mg is a highly selective, fast acting direct inhibitor of Factor Xa, a serine protease clotting factor in the coagulation cascade that plays a pivotal role in the coagulation pathway.  Factor Xa converts prothrombin to thrombin, which leads to the generation of fibrin, a fibrous protein that traps aggregated platelets resulting in clot formation.  Apixaban in Eliquis tablets 5mg prevents thrombin generation and thrombus development at doses that that does not interfere with haemostasis, which is the normal control of bleeding

What are the side effects of Eliquis?

The most commonly reported side effects when taking Eliquis tablets 5mg include haemorrhage, contusion (bruising in the skin due to damage to small blood vessels) epistaxis (nosebleeds), haematoma (bruising), Haematuria (blood in the urine), nausea.

When should Eliquis not be used?

You should not use Eliquis tablets 5mg if you:

  • are allergic to apixaban or any ingredients in Eliquis
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • liver disease associated with increased blood coagulation
  • have any excessive bleeding or a condition that leads to increased bleeding, like gastrointestinal ulceration
  • have a malignant tumour at high risk of bleeding
  • have a prosthetic heart valve
  • are taking medicines that interact with Eliquis including ritonavir for HIV, the antifungal ketoconazole), other anticoagulants like heparin or warfarin, inhibitors of platelet aggregation like clopidogrel, heparin or warfarin, inhibitors of platelet aggregation like clopidogrel and NSAIDs like aspirin, the antiinfective rifampicin, the anticonvulsives carbamazepine and phenytoin, the sedative phenobarbital the herbal remedy St. John’s Wort

What medications interact with Eliquis?

Several medications interact with Eliquis tablets 5mg and should either not be taken while you are taking Eliquis or only after discussion and instruction from your doctor:

  • Drugs that increase bleeding when taken with Eliquis: ritonavir for HIV, the antifungal ketoconazole), other anticoagulants like heparin or warfarin, inhibitors of platelet aggregation like clopidogrel and NSAIDs like aspirin,
  • Drugs that affect Eliquis: ritonavir for HIV, the antifungal ketoconazole), other anticoagulants like heparin or warfarin, inhibitors of platelet aggregation like clopidogrel and NSAIDs like aspirin, the antiinfective rifampicin, the anticonvulsives carbamazepine and phenytoin, the sedative phenobarbital the herbal remedy St. John’s Wort for depression

How should Eliquis be taken?

You should take your Eliquis tablets 5mg swallowed whole with a glass of water, with food, or crushed into food if swallowing is difficult.  The dose you take, how often (once or twice daily) and for how long depends on what you are being treated for and your doctor’s recommendation.  You should continue to take your Eliquis tablets 5mg for as long as recommended by your doctor, which may be for several days or weeks.

How long should you take Eliquis?

You should continue to take your Eliquis tablets 5mg for as long as recommended by your doctor, which may be for several days or weeks.

Missed dose of Eliquis

If you miss a dose of Eliquis tablets 5mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Eliquis be stored?

You should store your Eliquis tablets 5mg below 25°C in a cool dry place. 

 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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