Micreme-H (Miconazole/Hydrocortisone) Cream

Micreme-H general information

What is Micreme-H used for?

Micreme-H is a topical skin cream used to treat fungal infections of the skin where there are symptoms of inflammation.  Micreme-H is effective against fungal infections due to the dermatophyte fungus tinea, that affects many parts of the body causing infections like athlete's foot (tinea pedis), ringworm or tinea of the body (tinea corporis), and tinea of the groin or jock itch (tinea cruris).  Also fungal infections of the skin due to the yeast Candida, which causes cutaneous candidiasis, characterised by itchy red rash on various parts of the body, usually in warm, moist creased areas of skin, like under the arms and in the groin.  Micreme-H Cream is also effective against some bacterial infections where there is inflammation, also mycotic infections with bacterial superinfection (another infection on top of the first infection).  Micreme-H Cream helps clear the infection and relieve symptoms of infection and inflammation such as itching, redness, dryness, crusting, scaling and discomfort.

How does Micreme-H work?

Micreme-H contains a combination of two medications that are used to treat inflamed fungal infections.  Miconazole in Micreme-H is a broad-spectrum antifungal drug, belonging to the imidazole group, which also has antibacterial activity.  It is absorbed through the skin and kills the fungus by inhibiting the synthesis of ergosterol, an important component of the fungal cell membrane that is not found in animal cells.  Miconazole in Micreme-H weakens the fungal cell membrane, causing the cell contents to leak out, which kills the fungus, preventing the infection from spreading and relieving symptoms of the infection, particularly itching.  Hydrocortisone in Micreme-H is a corticosteroid antiiflammatory that works by blocking the production of inflammatory chemicals, like prostaglandins and leukotrienes, which are hormone-like substances involved in the inflammatory process.  Hydrocortisone in Micreme-H also narrows and constricts blood vessels that have become dilated (widened) and leaky, allowing other inflammatory cells into the skin to escalate the inflammatory response.  This action of hydrocortisone in Micreme-H reduces symptoms of inflammatory skin conditions, including redness and irritation.  The antifungal miconazole and the corticosteroid hydrocortisone, work together in combination to clear up the infection and relieve symptoms of the infection and inflammation.   

What does Micreme-H contain?

Micreme-H cream contains the active ingredients, miconazole (2%) a broad-spectrum antifungal drug and hydrocortisone (1%) a corticosteroid anti-inflammatory that are used in combination to treat fungal infections that have become inflamed.  It also contains octyldodecanol, cetostearyl alcohol, cetyl esters wax, sorbitan monostearate, polysorbate 60, benzyl alcohol and purified water.

Treating fungal infections of the skin with Micreme-H

Micreme-H is a topical cream that contains miconazole, a broad-spectrum antifungal drug and hydrocortisone, a corticosteroid anti-inflammatory that are used in combination to treat fungal infections of the skin where there are symptoms of inflammation.  These include fungal infections due to the dermatophyte fungus tinea, that affects many parts of the body causing infections like athlete's foot (tinea pedis), ringworm or tinea of the body (tinea corporis), and tinea of the groin or jock itch (tinea cruris).  Also fungal infections of the skin due to the yeast Candida, which causes cutaneous candidiasis, characterised by itchy red rash on various parts of the body, usually in warm, moist creased areas of skin, like under the arms and in the groin.  Miconazole in Micreme-H is a broad-spectrum antifungal drug and works by inhibiting the synthesis of ergosterol, an important component of the fungal cell membrane, which weakens the fungal cell membrane, causing the cell contents to leak out, killing the fungus, preventing the infection from spreading.  Hydrocortisone in Micreme-H is a corticosteroid antiiflammatory that works by blocking the production of inflammatory chemicals, like prostaglandins and leukotrienes, which are hormone-like substances involved in the inflammatory process.  Hydrocortisone in Micreme-H also narrows and constricts causes blood vessels that have become dilated (widened) and leaky allowing other inflammatory cells into the skin to escalate the inflammatory response.  This action hydrocortisone in Micreme-H of reduces symptoms of inflammatory skin conditions, including redness and irritation.  Micreme-H Cream helps clear the infection and relieve symptoms of infection and inflammation such as itching, redness, dryness, crusting, scaling and discomfort.

What are the side effects of Micreme-H?

The most commonly reported side effects when taking Micreme-H cream include skin irritation at the site of application such as burning sensation, rash and itching.

When should Micreme-H not be used?

You should not use Micreme-H cream if you:

• are allergic to miconazole or hydrocortisone or any ingredients in Micreme-H
• are pregnant or are breastfeeding
• have kidney or liver disease
• are taking anticoagulants like warfarin that be affected by Micreme-H

How should Micreme-H be used?

You should apply your Micreme-H cream to the affected area once or twice daily, morning and evening. Rub in gently with a clean finger until all the cream is absorbed.  Wash your hands to prevent spreading the infection and do not get the cream into your eyes. You should continue applying your Micreme-H cream until all symptoms have cleared, but for no longer than 2 weeks.

How long should you take Micreme-H?

You should continue applying your Micreme-H cream until all symptoms have cleared, but for no longer than 2 weeks.

Missed dose of Micreme-H

If you miss a dose of Micreme-H apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose.  Do not apply a double dose.

How should Micreme-H be stored?

You should store your Micreme-H below 25°C in a cool dry place.