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Cerenia Injectable Solution (Maropitant citrate 10mg/ml) 20 Vial


Cerenia Injectable Solution (Maropitant citrate 10mg/ml) 20 Vial

Cerenia Injectable Solution 10mg/ml


Product Name
Cerenia Injectable Solution (Maropitant citrate 10mg/ml) 20 Vial
Active Ingredient
Maropitant citrate
Manufacturer
Zoetis
Product Type
Antiemetic
Product expiry date we are currently shipping
Jul 2020

Cerenia Injectable Solution contains maropitant, a novel class of broad-spectrum antiemetic that is used to treat and prevent vomiting in dogs and cats caused by a wide range of emetogenic stimuli (causing emesis or vomiting). 

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Cerenia (Maropitant) Injection 10mg/ml (20ml/Vial) 1 Vial
$6.65 per mL
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$266.00 (USD)
$133.00 (USD)
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$266.00 (USD)
$133.00 (USD)
SALE 50% OFF 
Cerenia (Maropitant) Injection 10mg/ml (20ml/Vial) 2 Vials
$6.54 per mL
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$523.00 (USD)
$261.50 (USD)
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$523.00 (USD)
$261.50 (USD)
SALE 50% OFF 
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Cerenia general information

What is Cerenia used for?

Cerenia Injectable Solution is a broad-spectrum antiemetic used to treat acute vomiting in dogs 2-4 months and older, and cats 4 months or older; also to prevent vomiting in dogs.  Most antiemetics have been developed for use in people and are not suitable for small animals.  Cerenia Injectable Solution is a novel class of antiemetic specifically developed to prevent and treat acute vomiting in dogs and cats.  There are many causes for vomiting, including systemic disorders, such as gastroenteritis or acute pancreatitis; bacterial infection such as leptospirosis; drug side effects such as anticancer drugs like cisplatin; motion sickness; or a clinical condition such as renal failure, adrenal insufficiency, intestinal obstruction or a central nervous system disease; also for treatment of vomiting in cats.  Cerenia Injectable Solution can also be used to prevent vomiting caused by opioid drugs given before surgery to dogs and can therefore be used to prevent preoperative vomiting; also to prevent vomiting due to an emetogenic medication such as for chemotherapy.  It is important that the underlying cause for the vomiting be investigated and if it persists, consult your veterinary professional.  

How does Cerenia work?

Cerenia Injectable Solution contains maropitant, a novel class of broad-spectrum antiemetic that is used to treat and prevent vomiting in dogs and cats caused by a wide range of emetogenic stimuli (causing emesis or vomiting).  Vomiting is a complex process that is coordinated centrally within the central nervous system (CNS) by the vomiting or emetic centre, situated in the brainstem and comprising the area postrema and other nuclei (collection of nerve cells or neurons).  The vomiting centre receives and responds to sensory stimuli transmitted by central and peripheral nerves, which initiates the vomiting process including contraction of smooth muscle in the digestive tract.  The chemoreceptor trigger zone is also situated in the area postrema and induces vomiting in response to emetic drugs, such as chemotherapy drugs.  Maropitant in Cerenia Injectable Solution is a potent and selective neurokinin (NK1) receptor antagonist that blocks the pharmacological action of substance P, a neurotransmitter that plays an important role in emesis.  A neurotransmitter is a chemical messenger that allows nerve cells to communicate.  Substance P is a tachykinin neurotransmitter found in high concentration in the area postrema of the brain and is also found in the peripheral nervous system as well as in other sites such as the gastrointestinal tract.  Substance P acts by stimulating its NK1 receptor to induce vomiting.  Maropitant in Cerenia Injectable Solution mimics the structure of Substance P and binds to the NK1 receptor, blocking the action of Substance P and thereby blocking the signal to induce vomiting from both the central nervous system (CNS) (brain and spinal cord) and peripheral nervous system (nerves and ganglia outside the CNS).  Cerenia Injectable Solution has rapid onset of action (within one hour) and lasts for 24hours and is, therefore, suitable for once daily treatment.  

What does Cerenia contain?

Cerenia Injectable Solution contains the active ingredient maropitant citrate, a broad-spectrum antiemetic that is used to treat and prevent vomiting in dogs and cats caused by a wide range of emetogenic stimuli.  Each ml of Cerenia Injectable Solution contains 10 mg maropitant, 63 mg sulphobutylether-beta-cyclodextrin, 3.3 mg meta-cresol and water for injection.

Treating vomiting in dogs and cats with Cerenia

Maropitant in Cerenia Injectable Solution contains maropitant, a broad-spectrum antiemetic that is used to treat acute vomiting in dogs 2-4 months and older and cats 4 months or older; also to prevent vomiting in dogs, and is effective for central and peripheral causes of emesis (vomiting).  There are many causes for vomiting, including gastroenteritis, bacterial infection, side effects of anticancer drugs, motion sickness or a clinical condition such as renal failure.  Cerenia Injectable Solution can also be used to prevent vomiting caused by opioid drugs given to dogs before surgery and can therefore be used to prevent preoperative vomiting; also to prevent vomiting due to an emetogenic medication such as for chemotherapy.  Vomiting is a complex process that is coordinated by the vomiting or emetic centre in the brain.  Maropitant in Cerenia Injectable Solution is a potent and selective neurokinin (NK1) receptor antagonist that blocks the pharmacological action of substance P, a neurotransmitter (chemical messenger) that plays an important role in vomiting and is found in high concentration in the emetic centre.  Maropitant in Cerenia Injectable Solution binds to the NK1 receptor blocking the action of Substance P and thereby, blocking the signal to induce vomiting from both the central nervous system (CNS) (brain and spinal cord) and peripheral nervous system (nerves and ganglia outside the CNS).  Cerenia Injectable Solution has rapid onset of action (within one hour) and lasts for 24hours and is, therefore, suitable for once daily treatment. 

What are the side effects of Cerenia?

The most commonly reported side effects for dogs and cats taking Cerenia Injectable Solution include hypersalivation, diarrhoea, lethargy, loss of appetite, fever, flatulence, irritation or pain at the site of injection.

When should Cerenia not be used?

You should not give Cerenia Injectable Solution to your pet if your pet:

  • is allergic to maropitant or any ingredients in Cerenia
  • Is pregnant or lactating
  • has liver disease
  • has gastrointestinal obstruction
  • has ingested toxins
  • has bradycardia (low blood pressure) or underlying heart disease
  • is taking calcium channel blockers, if a high dose of Cerenia is used
  • is taking vincristine for cancer treatment 
  • is taking plasma protein-bound medicines that interact with Cerenia, including NSAIDs, cardiac, anticonvulsant, and behavioural medications, without discussion with your vet who should be monitoring drug compatibility

How should Cerenia be given?

For prevention or treatment of acute vomiting in dogs 2-4 months or older Cerenia Injectable Solution should be administered by injection subcutaneously at a dose of 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight, once daily for up to 5 consecutive days.  For dogs older than 4 months the injection can be given intravenously over 1-2 minutes or subcutaneously.  For cats 4 months and older Cerenia Injectable Solution should be administered by injection subcutaneously intravenously over 1-2 minutes, at a dose of 1 mg/kg (0.45 mg/lb) equal to 0.1 mL/kg (0.1 mL/2.2 lb) of body weight, once daily for up to 5 consecutive days.  For prevention of vomiting due to an emetogenic medication such as for chemotherapy, Cerenia Injectable Solution can be administered 45-60 minutes before treatment. 

Note:

For dogs, Cerenia Injectable Solution may be used interchangeably with Cerenia tablets for treatment and prevention of acute vomiting, after initial treatment. 

How long should Cerenia be given?

For prevention or treatment of acute vomiting in dogs and cats Cerenia Injectable Solution should be administered for up to 5 consecutive days.

Missed dose of Cerenia

If you miss a dose of Cerenia Injectable Solution administer it as soon as you remember, unless it is time to administer the next dose, then skip the missed dose.  Do not administer a double dose.

How should Cerenia be stored?

You should store your Injectable Solution Cerenia between 20- 25°C in a cool dry place.  Once the vial has been punctured, store refrigerated at 2-8°C and use within 90 days.

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