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Nexium 40mg 14 Tablets/Pack


Nexium 40mg 14 Tablets/Pack

Nexium 40mg (Esomeprazole)


Product Name
Nexium 40mg 14 Tablets/Pack
Active Ingredient
Esomeprazole
Manufacturer
Astra Zeneca
Product Type
Proton pump inhibitor (gastric acid reduction)
Product expiry date we are currently shipping
Discontinued, no stock

This product has been discontinued, but we do have alternatives below.

Nexium tablets 40mg contain esomeprazole, used to treat symptoms of gastric reflux and to treat and heal gastric ulcers, by reducing gastric acid reduction.

Nexium general information

What is Nexium used for?

Nexium tablets 40mg are used to treat conditions caused by gastric reflux, which is when the acidic contents of the stomach flow back into the oesophagus (gullet), because the sphincter (muscle at the junction of the oesophagus and stomach) that normally acts as a one-way valve and prevents backflow of stomach contents, does not function properly or is damaged. Gastroesophageal reflux disease (GORD), as this condition is known, causes symptoms like heartburn and dyspepsia (indigestion and abdominal pain), and can damage the oesophagus causing inflammation (oesophagitis). Nexium tablets 40mg are also used to treat and prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and duodenum (duodenal ulcers or damage to the lining of the upper intestine); and gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAID); also as combination therapy to treat gastric ulcers that are caused by infection of the stomach with the bacterium Helicobacter pylori, in conjunction with using antibiotics. Nexium tablets 40mg are also used to treat symptoms of acid-related dyspepsia that can be caused by eating high fat or acidic foods, or Zollinger-Ellison syndrome in which increased levels of the hormone gastrin causes an excessive production of gastric acid.

How does Nexium work?

Nexium tablets 40mg contain esomeprazole, a proton pump inhibitor that is used to treat conditions caused by excess gastric acid, by reducing the amount of gastric acid released into the stomach. Stomach acid is needed for digestion of proteins in your diet and is made by the parietal cells of the stomach wall. Gastric acid production is dependent on the action of the enzyme H+/K+-ATPase, which is the proton pump responsible for pumping positive hydrogen ions out of the cells into the stomach, which increases the acidity of the stomach contents. Esomeprazole in Nexium tablets 40mg inhibits the functioning of the H+/K+-ATPase, which prevents acid secretion by blocking the source of acid production. This action of esomeprazole reduces the acidity of the stomach contents, which reduces the acid damage that can be caused by gastroesophageal reflux disease (GORD) and oesophagitis and relieves symptoms caused by excess gastric acid like heartburn and dyspepsia. By inhibiting gastric acid secretion Nexium tablets 40mg also help prevent the formation of gastric (stomach) and duodenal (upper intestine) peptic ulcers and also helps ulcers and damage caused by gastric reflux to heal.

What does Nexium contain?

Nexium tablets 40mg contain the active ingredient esomeprazole, which is a proton pump inhibitor that is used to treat conditions caused by excess gastric acid secretion.

Treating gastric reflux with Nexium

Nexium tablets 40mg contain esomeprazole, which is used to treat conditions caused by gastroesophageal reflux disease (GORD). Gastric reflux is when the acidic contents of the stomach flow back into the oesophagus (gullet), because the sphincter (muscle at the junction of the oesophagus and stomach) that normally acts as a one-way valve and prevents backflow of stomach contents, does not function properly or is damaged. Symptoms caused by gastric reflux include heartburn and dyspepsia (indigestion and abdominal pain), and damage to the oesophagus causing inflammation (oesophagitis). Esomeprazole in Nexium tablets 40mg reduces acid secretion by parietal cells of the stomach wall, by blocking the action of the enzyme H+/K+-ATPase, which is responsible for acid production. This action of esomeprazole reduces the acidity of the stomach contents, which reduces the acid damage that can be caused by gastroesophageal reflux disease (GORD) and oesophagitis, relieves symptoms caused by excess gastric acid like heartburn and dyspepsia; as well as helping damaged tissues caused by excess acid to heal.

Nexium for peptic ulcers

Nexium tablets 40mg contain the active ingredient esomeprazole, which is used to treat and prevent prevent peptic ulcers in the stomach (gastric ulcers or damage to the stomach lining) and duodenum (duodenal ulcers or damage to the lining of the upper intestine), caused by excess secretion of gastric acid; and gastric ulcers caused by use of nonsteroidal anti-inflammatory drugs (NSAID). Nexium tablets 40mg are also used as combination therapy to treat and prevent gastric ulcers that are caused by infection of the stomach with the bacterium Helicobacter pylori, in conjunction with using antibiotics. Esomeprazole in Nexium tablets 40mg reduces acid secretion by parietal cells of the stomach wall, by blocking the action of the enzyme H+/K+-ATPase, which responsible for acid production. This action of esomeprazole reduces the acidity of the stomach contents, which reduces the acid damage to the stomach wall and allows ulcers that have already developed to heal.

What are the side effects of Nexium?

The most commonly reported side effects when taking Nexium tablets 40mg, include: constipation, nausea, vomiting, diarrhoea, wind (flatulence), headache, dry mouth, skin rash, dizziness, sensation of tingling in the skin (paraesthesia), insomnia.

When should Nexium not be used?

You should not use Nexium if you:
  • are allergic to esomeprazole, any other proton pump inhibitor or any ingredients in Nexium
  • taking medication that interacts with Nexium, including: the antifungals ketoconazole and itraconazole, the anticoagulant warfarin, phenytoin for epilepsy, the antiretroviral atazanavir, the antibiotic clarithromycin, the immunosuppressive tacrolimus, the sedative diazepam

How should Nexium be taken?

You should take your Nexium tablets 40mg with a glass of water at least one hour before a meal. You should continue to take your Nexium tablets 40mg for as long as recommended by your doctor, usually for a few weeks to 6 months, depending on the condition you are being treated for.

How long should you take Nexium?

You should continue to take your Nexium tablets 40mg for as long as recommended by your doctor, usually for a few weeks to 6 months, depending on the condition you are being treated for.

Missed dose of Nexium

If you miss a dose of Nexium tablets 40mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Nexium be stored?

You should keep your Nexium tablets 40mg in their packs until use and store below 30°C in a cool dry place.

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