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Cordarone X (Amiodarone 100mg) 30 Tablets/Pack


Cordarone X (Amiodarone 100mg) 30 Tablets/Pack

Cordarone X (Amiodarone 100mg) Tablets


Product Name
Cordarone X (Amiodarone 100mg) 30 Tablets/Pack
Active Ingredient
Amiodarone
Manufacturer
Sanofi-Aventis
Product Type
Antiarrythmic agent
Product expiry date we are currently shipping
Aug 2020

Cordarone X tablets 100mg contain amiodarone, a class III antiarrhythmic that is used to treat severe tachyarrhythmia due to rhythm disorders of the heart.

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Cordarone X (Amiodarone) 100mg 30 Tablets
$0.41 per Tablet
|
$24.50 (USD)
$12.25 (USD)
SALE 50% OFF 
$24.50 (USD)
$12.25 (USD)
SALE 50% OFF 
Cordarone X (Amiodarone) 100mg 60 Tablets
$0.36 per Tablet
|
$43.50 (USD)
$21.75 (USD)
SALE 50% OFF 
$43.50 (USD)
$21.75 (USD)
SALE 50% OFF 
Cordarone X (Amiodarone) 100mg 90 Tablets
$0.70 per Tablet
|
$63.00 (USD) 
$63.00 (USD) 
Cordarone X (Amiodarone) 100mg 120 Tablets
$0.68 per Tablet
|
$81.50 (USD) 
$81.50 (USD) 
Cordarone X (Amiodarone) 100mg 150 Tablets
$0.66 per Tablet
|
$99.00 (USD) 
$99.00 (USD) 
Cordarone X (Amiodarone) 100mg 180 Tablets
$0.64 per Tablet
|
$116.00 (USD) 
$116.00 (USD) 

Cordarone X general information

What is Cordarone X used for?

Cordarone X tablets 100mg are used to treat severe tachyarrhythmia, which is a rhythm disorder of the heart, where the heartbeat is fast and irregular due to abnormal electrical activity; it is only used when there is insufficient response to other treatments or when other treatments are contraindicated and cannot be used.  Conditions where Cordarone X tablets 100mg are used include tachyarrhythmias associated with Wolff-Parkinson-White Syndrome, which is an inherited disorder of the electrical system of the heart that transmits impulses to make the heart muscle contract.  An extra pathway of the electrical system shortcuts the normal electrical pathway, causing the electrical impulse to continue instead of fade as in a normal heartbeat and this is also known as re-entry tachycardia.  Atrioventricular nodal tachycardia is another example of re-entry tachycardia and is also the most common form of supraventricular tachycardia.  The electrical impulse begins in or near the atrioventricular (AV) node, which normally conducts electrical impulses between the upper (atrial) and lower (ventricular) chambers of the heart and regulates this electrical activity.  Cordarone X tablets 100mg are also used to treat atrial fibrillation and atrial flutter.  Atrial fibrillation is an arrhythmia of the upper chambers of the heart (atria) and can be permanent or paroxysmal, meaning it is episodic and the episode of arrhythmia begins and ends abruptly.  Atrial flutter is when the atrial chambers beat regularly but faster and more often than the lower chambers (ventricles).  Both are types of supraventricular tachycardia.  Cordarone X tablets 100mg are also used to treat ventricular arrhythmia and ventricular fibrillation, if considered treat life-threatening.  In ventricular arrhythmia, the abnormal electrical impulse originates in the lower (ventricular) chambers of the heart and is caused by the ventricles contracting too fast or irregularly, preventing the supply of oxygen-rich blood circulating efficiently to the heart itself and the rest of the body.  This increases the workload on the heart, which also increases the demand for oxygen and can result in ischemia (restriction of oxygen to the tissues) and heart attack.  Ventricular fibrillation, which can be initiated by a heart attack, is rapid irregular electrical impulses and causes the heart muscles to quiver instead of contract which prevents the heart from pumping and can result in cardiac arrest. Cordarone X tablets 100mg suppress and stabilise abnormal rhythms of the heart and restore rhythm control, to relieve symptoms of arrhythmias including palpitations, shortness of breath and fatigue, and reduce risk of stroke, heart failure and heart attack. 

How does Cordarone X work?

Cordarone X tablets 100mg contain amiodarone, a class III antiarrhythmic that is used to treat severe tachyarrhythmia due to rhythm disorders of the heart, with a broad spectrum of activity effective in controlling tachyarrhythmias in atrial, nodal and ventricular tissues.  Amiodarone in Cordarone X tablets 100mg works by slowing down the electrical signals that cause tachycardia, by blocking the potassium channels in the heart muscle cells (cardiac myocytes) that cause repolarisation of the heart during phase 3 of the cardiac action potential, which is how the passage of electrical impulses through the heart muscle is conducted to cause the heart to contract.  This action of Amiodarone in Cordarone X tablets 100mg prolongs the duration of the action potential and increases the refractory period, which is the time between action potentials, when the myocytes are not excitable.  This contributes to the slowing down of the heartbeat and control of tachyarrhythmias, particularly re-entry tachycardia, in which new action potentials are generated prematurely.  The effects of Amiodarone in Cordarone X tablets 100mg are evident on an ECG as prolongation of the QRS duration (the stages of the action potential due to depolarisation of the left ventricle of the heart) and QT interval (ventricular activity including depolarisation and repolarisation), which are measures of normal electrical activity of the heart muscle.  Unlike other class III antiarrhythmics, amiodarone also binds to beta-adrenergic receptors, calcium channels, and sodium channels which results in beta blocker, calcium channel blocker and sodium channel blocker properties, and can cause unwanted side effects.  

What does Cordarone X contain?

Cordarone X tablets 100mg contain the active ingredient amiodarone, a class III antiarrhythmic used to treat severe rhythm disorders of the heart.  They also contain colloidal silicon dioxide, lactose monohydrate, magnesium stearate, maize starch, povidone.

Treating tachyarrhythmia with Cordarone X

Cordarone X tablets 100mg contain amiodarone, a class III antiarrhythmic that is used to treat severe tachyarrhythmia due to rhythm disorders of the heart, when there is insufficient response to other treatments or when other treatments are contraindicated and cannot be used.  Amiodarone in Cordarone X tablets 100mg has a broad spectrum of activity and is effective in controlling tachyarrhythmias in upper (atrial) and lower (ventricular) chambers of the heart; also the atrioventricular node that connects the two chambers.  Tachyarrhythmia is due to abnormal electrical activity causing the heartbeat to become fast and irregular.  Amiodarone in Cordarone X tablets 100mg is used to treat various forms of tachyarrhythmia, including re-entry tachycardia, which is caused by an extra pathway of the electrical system that shortcuts the normal electrical pathway, such as in Wolff-Parkinson-White Syndrome and atrioventricular nodal tachycardia.  Cordarone X tablets 100mg are also used to treat atrial fibrillation and atrial flutter, which are due to abnormal electrical activity originating in the atrial chambers; also ventricular arrhythmia and fibrillation, where the abnormal electrical impulse originates in the ventricular chambers, which is the most life-threatening form of tachyarrhythmia and can result in cardiac arrest.  Amiodarone in Cordarone X tablets 100mg works by acting directly on the heart muscle cells (myocytes) to prolong the duration of the action potential (the electrical impulse that causes myocytes to contract) and increases the refractory period, which is the time between action potentials.  This action of amiodarone in Cordarone X tablets 100mg slows down the electrical signals that cause tachycardia, thereby slowing down the heartbeat.  Cordarone X tablets 100mg suppress and stabilise abnormal rhythms of the heart and restore rhythm control, to relieve symptoms of arrhythmias including palpitations, shortness of breath and fatigue, and reduce risk of stroke, heart failure and heart attack. 

What are the side effects of Cordarone X?

The most commonly reported side effects when taking Cordarone X tablets 100mg include gastrointestinal upset (nausea, vomiting), constipation, distorted sense of taste (dysgeusia), bradycardia (slow heartbeat), thyroid disorders (hypothyroidism and hyperthyroidism), reversible corneal microdeposits, tremor, insomnia, sleep disorders, lung disorders including pneumonitis (inflammation of the lung), pleuritis (inflammation of the pleural membranes surrounding the lungs), bronchiolitis obliterans organising pneumonia ( a serious inflammatory lung condition), photosensitivity and bluish discolouration of the skin, liver disorders. 

When should Cordarone X not be used?

You should not use Cordarone X tablets 100mg if you:

  • are allergic to amiodarone or any ingredients in Cordarone X
  • are pregnant or are breastfeeding
  • have liver disease
  • have a thyroid disorder, as Cordarone X contains iodine and has a direct toxic effect on the thyroid
  • have hypotension (low blood pressure), severe respiratory failure or heart failure
  • having a general anaesthetic
  • are taking medicines that interact with Cordarone X including other antiarrhythmics, anti-psychotics like pimozide and haloperidol, anti-depressants like amitriptyline, lithium for mood disorders, antihistamines like terfenadine and astemizole, anti-malarials like quinine, quinolone antibiotics like moxifloxacin, beta blockers like propranolol, calcium channel blockers like diltiazem, verapamil, stimulant laxatives like bisacodyl, some diuretics, systemic corticosteroids, the antifungal amphotericin B given intravenously, digoxin for heart conditions, anticoagulants like warfarin and dabigatran, antivirals like sofosbuvir for HIV

What medications interact with Cordarone X?

Several medications interact with Cordarone X tablets 100mg and should either not be taken while you are taking Cordarone X or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with Cordarone X: other antiarrhythmics, anti-psychotics like pimozide and haloperidol, anti-depressants like amitriptyline, lithium for mood disorders, antihistamines like terfenadine and astemizole, anti-malarials like quinine, quinolone antibiotics like moxifloxacin, beta blockers like propranolol, calcium channel blockers like diltiazem, verapamil, stimulant laxatives like bisacodyl, some diuretics, systemic corticosteroids, the antifungal amphotericin B given intravenously
  • Drugs that affect Cordarone X: antivirals like sofosbuvir for HIV
  • Drugs that are affected by Cordarone X: digoxin for heart conditions, anticoagulants like warfarin and dabigatran

How should Cordarone X be taken?

You should take your Cordarone X tablets 100mg swallowed whole with a glass of water, with or without food, three times daily for one week, then twice daily for another week.  The dose you take and how often may be adjusted depending on your doctor’s recommendation and if you experience side effects.  You should continue to take your Cordarone X tablets 100mg for as long as recommended by your doctor.

How long should you take Cordarone X?

You should continue to take your Cordarone X tablets 100mg for as long as recommended by your doctor.

Missed dose of Cordarone X

If you miss a dose of Cordarone X tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Cordarone X be stored?

You should store your Cordarone X tablets 100mg below 25°C in a cool dry place. 

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