Toxo-Mox 500 (Amoxycillin & Potassium Clavulanate 400mg/100mg) Tablets

Toxo-Mox general information

What is Toxo-Mox used for?

Toxo-Mox tablets 500mg are a combination veterinary antibiotic used for short-term treatment of a wide range of bacterial infections commonly found in cats and dogs.  These include skin disease, such as deep and superficial pyodermas, which are infections of the skin where bacteria have entered a cut, or a wound causing symptoms like itching, pustules (inflamed pus filled swelling), hair loss, raised lesions, dried discharge.  Toxo-Mox 500 is also used to treat urinary tract infections, upper and lower respiratory tract infection and enteritis (inflammation of the small intestine). 

How does Toxo-Mox work?

Toxo-Mox tablets 500mg contain a combination of two antibiotics.  Amoxycillin is as an antibiotic similar to penicillin and belongs to the beta-lactam group of antibiotics, which block the formation of the bacterial cell wall and this kills the bacteria.  However, amoxycillin can be inactivated by the bacterial enzyme beta-lactamase that makes certain bacteria resistant to amoxycillin.  Clavulanic acid is an antibiotic structurally related to the penicillins that is able to inactivate a wide range of beta-lactamase enzymes commonly found in amoxycillin-resistant bacteria.  This dual action of Toxo-Mox tablets provides a broad spectrum antibiotic and a beta-lactamase inhibitor, which extends the range of susceptible bacteria.  Toxo-Mox 500 is effective against a wide range of bacteria, including susceptible Staphylococci, Streptococci and Escherichia coli, and is used to treat infections common to cats and dogs caused by these bacteria.

What does Toxo-Mox contain?

Toxo-Mox tablets contains the active ingredients amoxycillin (400mg) and clavulanic acid (100mg), used to treat a wide range of common bacterial infections in cats and dogs. 

Treating bacterial infection in cats and dogs with Toxo-Mox

Toxo-Mox tablets 500mg contain a combination of two antibiotics, amoxycillin, that kills bacteria, and clavulanic acid that inactivates the beta-lactamase enzyme commonly found in amoxycillin-resistant bacteria and therefore helps prevent resistance to amoxycillin.  Toxo-Mox tablets 500mg are used for short-term treatment of a wide range of bacterial infections commonly found in cats and dogs.  These include skin diseases, such as deep and superficial pyodermas, which are infections of the skin where bacteria have entered a cut or a wound causing symptoms like itching, pustules (inflamed pus filled swelling), hair loss, raised lesions, dried discharge.  Toxo-Mox 500 is also used to treat urinary tract infections, upper and lower respiratory tract infection and enteritis (inflammation of the small intestine).

What are the side effects of Toxo-Mox?

The most commonly reported side effects when taking Toxo-Mox tablets 500mg include gastrointestinal symptoms including diarrhoea and vomiting, also loss of appetite.

When should Toxo-Mox not be used?

You should not give Toxo-Mox tablets 500mg to your cat or dog if they:

• show signs of allergic reaction or hypersensitivity to amoxycillin or have had a reaction with any other beta-lactams antibiotic, including cephalosporins or clavulanic acid or any ingredients in Toxo-Mox
• are pregnant or lactating, without discussion with your vet
• have kidney problems that causes them to produce less urine than normal
• have liver problems

How should Toxo-Mox be taken?

You should give Toxo-Mox 500mg orally to your dog or cat twice daily.  The recommended dose is 12.5mg/kg (6.25mg/lb) bodyweight twice daily.  The number of tablets per body mass works out as follows:

• 10-13kg (22-29 lb)              ¼ tablet
• 14-18kg (30-39 lb)               ½ tablets
• 19-25kg (41-55 lb                ½ -¾ tablet
• 26-35kg (57-77 lb)               ¾-1 tablet
• 36-50kg (79-110 lb)            1-1¼ tablet

You should continue to give Toxo-Mox tablets 500mg to your pet as recommended by your vet, usually for 5 to 7 days when you should see an improvement in your pet, or for 48 hours after all symptoms have gone.  If needed your vet may suggest a longer course of treatment, for example, 10-20 days for chronic skin disease, 10-28 days for chronic cystitis, 8-10 days for respiratory disease.

How long should Toxo-Mox be given?

You should continue to give Toxo-Mox tablets 500mg to your pet as recommended by your vet, usually for 5 to 7 days when you should see an improvement in your pet, or for 48 hours after all symptoms have gone.  If needed your vet may suggest a longer course of treatment, for example, 10-20 days for chronic skin disease, 10-28 days for chronic cystitis, 8-10 days for respiratory disease.

Missed dose of Toxo-Mox

If you miss a dose of Toxo-Mox tablets 500mg give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Toxo-Mox be stored?

You should store your Toxo-Mox tablets 500mg below 25°C in a cool dry place.