Suminat (Sumatriptan 100mg) Tablet
Suminat (Sumatriptan 100mg) Tablet
Also known as Imitrex or Imigran
Anti-migraine (serotonin agonist)
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Suminat general information
What is Suminat used for?
Suminat tablets 100mg are used to relieve acute migraine attacks with or without aura, which is the perception of visual disturbances and/or smells and are usually the first sign that a migraine headache is on its way. Suminat tablets 100mg are specific for treatment of migraine attack to relieve headache and other symptoms, including nausea and sensitivity to light, but they are not used to prevent migraine headaches. You can use Suminat 100 at any stage of a migraine attack but it is more effective if taken as soon as possible after the first signs of headache and/or aura. Suminat 100 is not effective for treatment of other types of headache.
How does Suminat work?
Suminat tablets 100mg contain sumatriptan, a serotonin agonist that is used to treat migraine headaches. Sumatriptan in Suminat tablets 100mg is a member of the group of drugs called triptans that mimics the action of serotonin (also known as 5-hydroxytryptamine, or 5-HT). Serotonin is a brain chemical that is involved in the control of mood, pain sensation, sexual behaviour and sleep; as well as constriction (narrowing) of blood vessels. Migraine is thought to be caused by dilatation or widening of blood vessels in the head due to one of many migraine triggers, which in turn stimulates nearby sensory nerves causing pain. Sumatriptan in Suminat 100 stimulates the serotonin receptors in these expanded blood vessels making them contract again (vasoconstriction) and inhibits trigeminal nerve activity, relieving pain. Both actions are thought to contribute to the anti-migraine action of sumatriptan to relieve headache and other symptoms of a migraine attack.
What does Suminat contain?
Suminat tablets 100mg contain the active ingredient sumatriptan, a serotonin agonist that is used to relieve symptoms of migraine headaches.
Treating migraine with Suminat
Suminat tablets 100mg contain sumatriptan, a serotonin agonist that mimics the action of serotonin, and are used to relieve acute migraine attacks with or without aura, which is the perception of visual disturbances and/or smells called and are usually the first sign that a migraine headache is on its way. Sumatriptan in Suminat 100 interacts with specific receptors on blood vessels in the head which have become vasodilated (widened), due to one of many possible migraine triggers, causing them to contract again back to normal. This action along with interaction with the trigeminal nerve to block pain, relieves the headache and other symptoms of migraine, including nausea and sensitivity to light.
What are the side effects of Suminat?
The most commonly reported side effects when taking Suminat tablets 100mg include dizziness, drowsiness, sensory disturbance including, tingling, pricking, or numbness of the skin (paraesthesia), loss of sensitivity to pain or touch (hypoaesthesia), shortness of breath, sensations of heaviness, pain, sensations of heat or cold, pressure or tightness, weakness, fatigue.
When should Suminat not be used?
You should not use Suminat tablets 100mg if you:
- are allergic to sumatriptan or any tryptan or any ingredients in Suminat
- have liver disease
- have high blood pressure (hypertension)
- have had myocardial infarction or have ischaemic heart disease, coronary vasospasm (Prinzmetal's angina), peripheral vascular disease, or a history of cerebovascular accident (CVA) or transient ischaemic attack (TIA
- are taking medicines that interact with Suminat including ergotamine or derivatives of ergotamine (including methysergide), monoamine oxidase inhibitors (MAOIs), antidepressants
What medications interact with Suminat?
Several medications interact with Suminat tablets 100mg and should either not be taken while you are taking Suminat or only after discussion and instruction from your doctor:
- Ergot derivatives including methysergide (also for migraine headaches) should not be taken 24 hours before to 6 hours after dose of Suminat
- Suminat should not be taken within 14 days of discontinuing MAOI antidepressants
- SSRI and SNRI antidepressants (also serotonin agonists) can cause serotonin syndrome
How should Suminat be taken?
You can take your Suminat tablets 100mg at any stage of a migraine attack but it is more effective if taken as soon as possible after the first signs of headache and/or aura. You should take one or two Suminat tablets 100mg as recommended by your doctor, swallowed whole with a glass of water, with or without food. You should not take another dose of Suminat 100 for the same migraine, but you can take another dose if you have another migraine attack in the next 24 hours, provided you do not take more than 300mg in a 24 hour period.
How should Suminat be stored?
You should store your Suminat tablets 100mg below 25°C in a cool dry place.