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Genox 20mg 100 Tablets/Pack


Genox 20mg 100 Tablets/Pack

Genox 20mg (Tamoxifen) 100's

 

Product Name
Genox 20mg 100 Tablets/Pack
Also known as Nolvadex
Active Ingredient
Tamoxifen
Manufacturer
Mylan (New Zealand)
Product Type
Anti-oestrogen
Product expiry date we are currently shipping
Discontinued, no stock

This product has been discontinued, but we do have alternatives below.

Genox tablets 20mg, contain the anti-oestrogen tamoxifen, used to treat breast cancer and endometrial cancer; to prevent spread of breast cancer and to reduce the risk of developing breast cancer in women at risk.

Genox general information

What is Genox used for?

Genox tablets 20mg (also known as Nolvadex and Tamofen) are used to treat breast cancer and endometrial cancer. Genox tablets 20mg reduce the growth of early stage tumours and can slow down the growth of advanced metastatic tumours that have already spread to other parts of the body, reducing mortality rates, particularly if taken continuously for 5 years. In women who have received other treatment for breast cancer, such as chemotherapy, Genox tablets 20mg are used as adjuvant therapy, to increase the chances of a cure and reduce the risk of breast cancer returning to the same breast or new tumours developing in the other breast. Genox tablets 20mg also reduce the risk of developing breast cancer in women who are at risk.

How does Genox work?

Genox tablets 20mg (also known as Nolvadex and Tamofen) contain tamoxifen, which is a non-steroidal anti-oestrogen, also known as a selective oestrogen receptor modulator (SERM), that binds to the oestrogen receptor on breast cancer cells blocks the action of oestrogen in these cells, which is to promote the development of beast cancer, and stimulate breast cancer cell growth. Most, but not all, breast cancers are sensitive to oestrogen and are known as oestrogen receptor-positive because they are oestrogen-dependent tumours and the cells contain oestrogen receptors. Genox tablets 20mg are more effective on oestrogen receptor-positive breast cancers and can block or slow down the growth of these tumours at early and late stages, as well as preventing the spread of advanced tumours to other parts of the body. Although tamoxifen in Genox tablets 10mg acts as an anti-oestrogen (antagonist) in breast cancers, it can act as an oestrogen agonist (mimic) in other cells, such as bone cells, which can provide some benefits, for example helping to maintain bone density and reducing the risk of osteoporosis (brittle bones), also reducing levels of blood total cholesterol, particularly in menopausal women.

What does Genox contain?

Genox tablets 20mg contain the active ingredient tamoxifen citrate, a non-steroidal anti-oestrogen that is used to treat breast cancer. They also also contain mannitol, maize starch, purified water, croscarmellose sodium and magnesium stearate.

Treating breast cancer with Genox

Genox tablets 20mg (also known as Nolvadex and Tamofen) contain tamoxifen that acts as anti-oestrogen and binds to the oestrogen receptor on breast cancer cells, blocking the action of oestrogen in oestrogen-dependent breast tumours. Genox tablets 20mg reduce the growth of early stage tumours and can slow down the growth of advanced metastatic tumours that have already spread to other parts of the body, reducing mortality rates, particularly if taken continuously for 5 years. In women who have received other treatment for breast cancer, such as chemotherapy, Genox tablets 20mg are used as adjuvant therapy, to increase the chances of a cure and reduce the risk of breast cancer returning to the same breast or new tumours developing in the other breast. Genox tablets 20mg can also reduce the risk of developing breast cancer in women who are at risk of developing breast cancer.

What are the side effects of Genox?

Most of the commonly reported side effects when using Genox tablets 20mg are generally mild and some are similar to menopausal symptoms; they include: hot flushes, vaginal bleeding, discharge and itching, fluid retention; also nausea, diarrhoea, indigestion, lightheadedness, skin rash, suppression of menstruation in pre-menopausal women.

What are the health risks of Genox?

There is an increased risk of blood clots when taking Genox tablets 20mg, particularly if you have received other treatments such as chemotherapy; also an increased risk of uterine cancer, just as there is when taking oestrogen for hormone replacement therapy.

When should Genox not be used?

You should not use Genox if you:
  • are allergic to tamoxifen or any ingredient in Genox tablets 20mg
  • are pregnant or planning to become pregnant
  • have had or have a history of abnormal blood clots, such as deep venous thrombosis, thromboembolic disorders, cerebral vascular accident associated with oestrogen
  • are taking other medications that may interact with Genox, including: anticoagulants like warfarin, other breast cancer medication like cytotoxic drugs (chemotherapy)

How should Genox be taken?

You should take Genox tablets 20mg with a glass of water and with food, once or twice a day, for as long as recommended by your doctor. Based on clinical triasl, Genox tablets 20mg get the best results when taken continuously for 5 years.

How long should you take Genox?

Based on clinical trials, Genox tablets 20mg get the best results when taken continuously for 5 years.

Missed dose of Genox

If you miss a dose of Genox tablets 20mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Genox be stored?

You should store your Genox tablets 20mg in their blister pack in a cool dry place, at room temperature below 25°C; keep away from direct sunlight.


All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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