Your Country: ?
Your Currency: ?
CONTACT US
USA: 877 271 6591
UK: 0808 234 7254
Outside UK/USA: 1 877 271 6591
Your Country: ?
Your Currency: ?
Login | SHOPPING CART    (0 items)
USA: 877 271 6591
UK: 0808 234 7254
Outside UK/USA: 1 877 271 6591
Your Country: ?
Your Currency: ?
Login | SHOPPING CART    (0 items)
FREE SHIPPING TO UNITED STATES
Topamate-100 100 Tablets/Pack


Topamate-100 100 Tablets/Pack

Topamate-100 (Topiramate)

 

Product Name
Topamate-100 100 Tablets/Pack
Active Ingredient
Topiramate
Manufacturer
Cipla Pharmaceuticals
Product Type
Anticonvulsant, Anti-epileptic
Product expiry date we are currently shipping
Discontinued, no stock

This product has been discontinued, but we do have alternatives below.

Topamate-100 general information

What is Topamate-100 used for?

Topamate-100 tablets 100mg are used to treat epilepsy in adults and children to control seizures, which happen when there is abnormal electrical activity in the brain. Topamate-100 tablets 100mg are used as monotherapy (on its own) for adults and children (over 6) who have just been diagnosed with idiopathic epilepsy (of unknown cause) and who have either generalised tonic-clonic seizures, seizures affecting the whole brain (formerly known as grand mal seizures), which usually last 1-3 minutes; or partial seizures, which affect only part of the brain but can spread to the whole brain and these are called secondarily generalised seizures. Topamate-100 is also used in addition to another medication for controlling seizures in adults and children (over 2 years of age) in partial onset seizures, generalised tonic-clonic seizures but who have been unable to achieve control of seizures with other medications; also in children for treatment seizures associated with of Lennox-Gastaut syndrome, a form of childhood-onset epilepsy that causes frequent seizures and developmental problems. Topamate-100 tablets 100mg are also used for the prevention of migraines in adults who have regular migraines (3 or more per month).

How does Topamate-100 work?

Topamate-100 tablets 100mg contain topiramate, an anticonvulsant used to treat epilepsy and control seizures. Nerve cells throughout the central nervous system communicate by sending out electrical signals, generated by the movement of electrically charged particles in and out of nerve cells, which travel to the all parts of the body via chemical messengers called neurotransmitters. This usually happens in an orderly fashion to control all our actions and thought processes. Epileptic seizures are thought to be caused by abnormal electrical activity in the brain, with uncontrolled, rapid and repetitive electrical signals being sent continually to various parts of the body, although the trigger for this abnormality is not known. Topiramate in Topamate-100 works directly on the brain cells to reduce the rate at which electrical signals are generated, by three different mechanisms. The effect is a calming of the overactive nerve activity. Conduction of electrical impulses is dependent on the flow of positive sodium ions into and out of the nerve cell through special sodium channels. Topiramate in Topamate-100 blocks these sodium channels and therefore reduces the neurone’s ability to send out continuous signals which cause seizures. Topiramate also has the ability to enhance the activity of gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter that regulates how much neurones can be excited (stimulated to send out electrical impulses), and inhibits the activity of the excitatory neurotransmitter glutamate, which adds to the calming effect on brain electrical activity. These three mechanisms are thought to contribute to the anticonvulsant activity of Topamate-100, which control seizures in epilepsy, but cannot cure them.

What does Topamate-100 contain?

Topamate-100 tablets 100mg contain the active ingredient topiramate, which is an anticonvulsant used to treat epilepsy and control seizures.

Treating epilepsy with Topamate-100

Topamate-100 tablets 100mg contain topiramate, an anticonvulsant used to treat epilepsy in adults and children to control tonic-clonic seizures, seizures affecting the whole brain (formerly known as grand mal seizures), and partial seizures, which affect only part of the brain but can spread to the whole brain and are called secondarily generalised seizures. Epileptic seizures happen when there is abnormal electrical activity in the brain, with uncontrolled, rapid and repetitive electrical signals being sent continually to various parts of the body, although the trigger for this abnormality is not known. Topiramate in Topamate-100 works directly on the brain to reduce the rate at which electrical signals are generated, by blocking the ability of nerve cells to transmit electrical signals. This action is thought to contribute to the anticonvulsant activity of Topamate-100 tablets 100mg, which prevent the overload of electrical activity in the brain that causes seizures in epilepsy and therefore controls the seizures, but cannot cure epilepsy.

Topamate-100 for preventing migraine

Topamate-100 tablets 100mg contain topiramate, an anticonvulsant that is used to treat epilepsy to control seizures. They are also used for the prevention of migraines in adults who have regular migraines (3 or more per month) that interfere with normal daily activities. Topiramate in Topamate-100 works directly on the brain to reduce the rate at which electrical signals are generated and reducing the transmission of electrical signals by over excitable nerve cells. This action of Topamate-100 is thought to contribute to the blocking of pain signals, which reduces the occurrence of a migraine headache. Topamate-100 tablets 100mg are not intended to treat a migraine attack but can control the number of migraine attacks if they happen regularly and frequently, to help you manage your daily life.

What are the side effects of Topamate-100?

The most commonly reported side effects when taking Topamate-100 tablets 100mg usually relate to the dose you are taking and include: unusual tiredness, drowsiness, weakness, dizziness; decrease in appetite or weight loss, slowness of thought processes (bradyphrenia), tingling and numbness of hands and feet (paresthesia); headache; nausea, diarrhoea, constipation; memory impairment; double vision (diplopia); inability to sleep; speech disturbances; anxiety and depression;

When should Topamate-100 not be used?

You should not use Topamate-100 if you:
  • are allergic to topiramate or any ingredients in Topamate-100
  • if you are pregnant or breastfeeding
  • have or have had kidney stones
  • have kidney disease or liver disease or glaucoma
  • have a psychiatric disorder
  • are taking medication that interact with Topamate-100, including: other epilepsy medicines like phenytoin or carbamazepine; digoxin for heart failure; CNS depressant medicines and alcohol; oral contraceptives; lithium and risperidone (for bipolar disorder and schizophrenia), the diuretic hydrochlorothiazide; metformin, pioglitazone, glibenclamide for diabetes; the anticonvulsant valproic acid
  • are taking any medicine which slows your reactions, such as medicines to help you sleep or relieve pain, antidepressants, tranquillisers or antihistamines which can make you drowsy

What medications interact with Topamate-100?

Several medications interact with Topamate-100 and should either not be taken while you are taking Topamate-100 only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction or increases side effects with Topamate-100: any medicine which slows your reactions (CNS depressants), such as medicines to help you sleep or relieve pain, antidepressants, tranquillisers or antihistamines which can make you drowsy and the effects may be worse when combines with Topamate-100; the anticonvulsant valproic acid can cause metabolic disturbances
  • Drugs that affect Topamate-100: other epilepsy medicines like phenytoin or carbamazepine; the diuretic hydrochlorothiazide
  • Drugs that are affected by Topamate-100; digoxin for heart failure; oral contraceptives; lithium and risperidone (for bipolar disorder and schizophrenia); metformin, pioglitazone, glibenclamide for diabetes

How should Topamate-100 be taken?

You should take your Topamate-100 tablets 100mg with a glass of water, with or without food, once daily preferably at the end of the day. Your doctor will probably start you on a low dose and then increase your dose, which may be taken as 2 tablets morning and evening, depending on how well you respond, what you are being treated for and your doctor’s recommendation. You should take your Topamate-100 continually for as long as recommended by your doctor, which may be for several months or longer and you should not stop taking your tablets, you will probably discontinue treatment gradually.

How long should you take Topamate-100?

You should take your Topamate-100 tablets 100mg continually for as long as recommended by your doctor, which may be for several months or longer.

Missed dose of Topamate-100

If you miss a dose of Topamate-100 tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Topamate-100 be stored?

You should store your Topamate-100 tablets 100mg in a cool, dry place at room temperature below 25°C.


See more products in
All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
What is this ?
Please select your country to display all the products we are able to supply to you.
What is this ?
Select the currency that you would like to display the prices in. This will be the currency that appears on your credit card statement.
 

This website uses cookies. View our policy and select your preferences here