Diclofenac Sandoz EC Tablets 25mg

Diclofenac Sandoz EC 25mg general information

What is Diclofenac Sandoz used for?

Diclofenac Sandoz enteric coated tablets 25mg are used to relieve pain and reduce inflammation in acute inflammatory
conditions. These conditions include flare-up of osteoarthritis, a degenerative joint disease caused by wear and tear that
has periods of remission and flare up. Also, non-articular rheumatism, which is pain that is not associated with joints and
include nerve entrapment and regional pain syndrome; rheumatic conditions of the connective tissue surrounding joints
(non-articular), including bursitis, tendinitis, tenosynovitis; as well as acute injury following trauma, such as sprains and
strains. Also, chronic musculoskeletal disorders, such as lower back pain (lumbago) and painful syndromes of the
vertebral column. Diclofenac Sandoz enteric coated tablets 25mg are also used to reduce pain, inflammation and swelling
following surgery, such as following dental or orthopaedic surgery; also, for acute attacks of gout and to relieve menstrual
pain or dysmenorrhoea or adnexitis (inflammation of the ovaries and fallopian tubes). Diclofenac Sandoz 50 is also used
as an adjuvant to treat severe painful inflammatory infections of the ear, nose, or throat, such as pharyngotonsillitis and
otitis, in addition to other medications. Diclofenac Sandoz enteric coated tablets 25mg are a short-term treatment to
relieve pain, inflammation and swelling in these acute conditions.

How does Diclofenac Sandoz work?

Diclofenac Sandoz enteric coated tablets 25mg contain diclofenac, which is a nonsteroidal anti-inflammatory drug
(NSAID) that has antirheumatic, anti-inflammatory, analgesic, and antipyretic (fever reducing) properties. Diclofenac in
Diclofenac Sandoz tablets 25mg blocks the production of specific chemicals called prostaglandins (PG) that mediate
inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) including cyclooxygenase 1
(COX-1) and cyclooxygenase 2 (COX-2). COX-2 is induced during the inflammation process and is responsible for the
synthesis of inflammatory prostaglandins, and inhibition of COX-2 helps relieve the symptoms of inflammation, including
pain, swelling, and joint stiffness. Inhibition of COX-1 is responsible for the gastrointestinal side effects that are due to
inhibition of protective prostaglandins in the gut and disruption of regulation of acid content. 

What does Diclofenac Sandoz contain?

Diclofenac Sandoz enteric coated tablets contain diclofenac sodium 25mg. They also contain Calcium hydrogen
phosphate dihydrate, Colloidal silicon dioxide, Iron oxide yellow, Lactose monohydrate, Magnesium stearate, Maize
starch, Methacrylic acid copolymer, Microcrystalline cellulose, Purified talc, Sodium starch glycolate, Titanium dioxide and
Triethyl citrate.

Treating pain and inflammation with Diclofenac Sandoz

Diclofenac Sandoz enteric coated tablets 25mg contain diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) that is
used to relieve pain and reduce inflammation in acute conditions. These include, flare-up of osteoarthritis, non-articular
rheumatism, (pain not associated with joints like nerve entrapment and regional pain syndrome, bursitis, tendinitis,
tenosynovitis, sprains and strains, lumbago, and painful syndromes of the vertebral column). Diclofenac Sandoz tab
enteric coated tablets 25mg are also used to reduce pain, inflammation and swelling following surgery, such as following
dental or orthopaedic surgery; also, for acute attacks of gout and to relieve menstrual pain or dysmenorrhoea or adnexitis
(inflammation of the ovaries and fallopian tubes). Diclofenac Sandoz enteric coated tablets 25mg are also used as an
adjuvant to treat severe painful inflammatory infections of the ear, nose, or throat, such as pharyngotonsillitis and otitis,
in addition to other medications. Diclofenac blocks the production of specific chemicals called prostaglandins (PG) that
mediate inflammation particularly PGE2 and works by inhibiting the enzyme cyclooxygenase. This action of diclofenac
in Diclofenac Sandoz tablets 25mg relieves symptoms of inflammation, including pain, swelling, and joint stiffness.

What are the side effects of Diclofenac Sandoz?

The most commonly reported side effects when taking Diclofenac Sandoz enteric coated tablets 25mg include
gastrointestinal upset (stomach or stomach pain, diarrhoea, indigestion, bloating, wind, heartburn, indigestion,
constipation) headache dizziness, vertigo, rash.

When should Diclofenac Sandoz not be used?

You should not use Diclofenac Sandoz enteric coated tablets 25mg if you:

• are allergic to diclofenac or any other NSAID including aspirin or any ingredients in Diclofenac Sandoz
• are pregnant or are breastfeeding
• have kidney or liver disease
• have any form of asthma including aspirin-induced asthma or rhinitis (runny itchy nose)
• have severe heart failure or have had a heart attack within the last 12 months
• have active or a history of gastrointestinal bleeding or perforation due to an ulcer
• have a tendency to bleed easily
• are taking medicines that interact with Diclofenac Sandoz including aspirin or other NSAIDs, anticoagulants like
warfarin or heparin, cholestyramine for high cholesterol, probenecid for gout, the anti-cancer drug methotrexate,
lithium for mood disorders, diuretics like frusemide, beta blockers for high blood pressure, digoxin for heart failure,
sulphonamide antibiotics, sulphonylureas for diabetes

What medications interact with Diclofenac Sandoz?

Several medications interact with Diclofenac Sandoz enteric coated tablets 25mg and should either not be taken while
you are taking Diclofenac Sandoz or only after discussion and instruction from your doctor:

• Drugs that cause a serious reaction with Diclofenac Sandoz: aspirin or other NSAIDs, the anti-cancer drug
methotrexate, anticoagulants like warfarin
• Drugs that affect Diclofenac Sandoz: cholestyramine for high cholesterol, probenecid for gout
• Drugs that are affected by Diclofenac Sandoz: anticoagulants like warfarin or heparin, the anti-cancer drug
methotrexate, lithium for mood disorders, diuretics like frusemide, beta blockers for high blood pressure, digoxin
for heart failure, sulphonamide antibiotics, sulphonylureas for diabetes.

How should Diclofenac Sandoz be taken?

You should take your Diclofenac Sandoz enteric coated tablets 25mg immediately after food. The dose you take depends
on what you are being treated for and your doctor’s recommendation and may be reduced or increased depending on
side effects and how well you respond. Typically the dose does not exceed one to two tablets taken immediately after
food up to three times daily. You should continue to take your Diclofenac Sandoz enteric coated tablets 25mg for as long
as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are
being treated for.

How long should you take Diclofenac Sandoz?

You should continue to take your Diclofenac Sandoz enteric coated tablets 25mg for as long as recommended by your
doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for.

Missed dose of Diclofenac Sandoz?

If you miss a dose of Diclofenac Sandoz enteric coated tablets 25mg take it as soon as you remember, unless it is time
to take the next dose, then skip the missed dose. Do not take a double dose.

How should Diclofenac Sandoz be stored?

You should store your Diclofenac Sandoz enteric coated tablets 25mg below 25°C in a cool dry place.