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Cardizem CD 180mg (Diltiazem)
Cardizem general information
What is Cardizem used for?
Cardizem capsules 180mg are used to treat hypertension, which is high blood pressure when at rest. Although there are usually no other symptoms, high blood pressure increases risk of cardiovascular disease. Cardizem CD capsules reduce the risk of stroke and heart attack, by lowering blood pressure to normal resting levels. Cardizem CD can be used alone or in combination with other antihypertensive medications such as diuretics. Cardizem capsules 180mg are also used to treat chronic stable angina, to prevent symptoms like chest pain and to prevent heart attack; also to treat angina due to coronary artery spasm, which is an acute angina attack which can occur at rest.
How does Cardizem work?
Cardizem capsules 180mg contain diltiazem, which is a calcium channel blocker that inhibits the inflow of calcium ions across specific calcium channels in the cell membrane into smooth muscle cells of the heart (myocardium) and blood vessel walls (only arteries). Calcium is needed for smooth muscle cells to contract, so by blocking calcium channels, smooth muscle cells contraction is prevented. Diltiazem in Cardizem capsules 180mg blocks calcium channels in smooth muscle cells, allowing peripheral arteries to relax and widen (vasodilation) and this reduces the workload on the heart, the force needed for the heart to pump blood around the body (negative inotropic effect), increases oxygen supply to the heart, and decreases blood pressure. Cardizem capsules CD also causes widening of the main arteries of the heart, increasing the oxygen supply to the heart and, as the heart workload is reduced, the demand for oxygen is also reduced, which prevents chest pain symptoms of angina caused by lack of oxygen to the heart muscle.
What does Cardizem contain?
Cardizem capsules 180mg contain the active ingredient diltiazem hydrochloride, a calcium channel blocker used to treat hypertension and angina, formulated for slow release over a 24 hours period. They also contain fumaric acid, purified talc, non-pareil seeds (sucrose), colloidal silica, white beeswax, ethylcellulose, castor oil, stearic acid, methacrylic acid copolymers, tributyl acetylcitrate, simethicone, gelatin, Brilliant Blue FCF CI 42090 and titanium dioxide.
What doses of Cardizem are available?
Cardizem CD capsules are available online form Inhouse Pharmacy in 3 doses:
- 120mg CDcapsule
- 180mg CD capsules
- 240mg CD capsules
Treating hypertension (high blood pressure) with Cardizem
Cardizem capsules 180mg contain diltiazem, a calcium channel blocker used to lower blood pressure in people with hypertension (high blood pressure at rest), who are at risk of cardiovascular disease due to high blood pressure, although there are usually no other symptoms. Cardizem capsules 180mg can either be used alone or in combination with other antihypertensive drugs such as diuretics. Diltiazem in Cardizem CD capsules 180mg blocks the inflow of calcium ions, needed for contraction, into smooth muscle cells of the heart and blood vessel walls (only arteries), which causes blood vessel walls to relax and peripheral arteries to widen. This action reduces the workload on the heart, which is the force needed for the heart to pump blood around the body, as measured by blood pressure. By lowering blood pressure Cardizem capsules 180mg help reduce risk of cardiovascular disease including stroke and heart attack.
Treating angina with Cardizem
Cardizem capsules 180mg contain diltiazem, a calcium channel blocker used to treat chronic stable angina and angina due to coronary artery spasm, which is an acute angina attack that can occur at rest. Diltiazem in Cardizem CD capsules 180mg blocks the inflow of calcium ions, needed for contraction, into smooth muscle cells of the heart and blood vessel walls (only arteries), which causes blood vessel walls to relax and peripheral arteries to widen. Cardizem capsules 180mg reduces the workload on the heart and its demand for oxygen, while at the same time increasing oxygen supply to the heart, which prevents chest pain symptoms of angina caused by lack of oxygen to the heart muscle.
What are the side effects of Cardizem?
The most commonly reported side effects when taking Cardizem capsules 180mg include: headache, dizziness, flushing, bradycardia (slow heart rate), gastrointestinal upset (nausea, vomiting, constipation, diarrhoea, indigestion, gastric pain) oedema (swelling of the ankles, feet, face or hands), flushing, palpitations, tiredness, weakness, drowsiness.
When should Cardizem not be used?
You should not use Cardizem capsules 180mg if you:
- are allergic to diltiazem, other calcium channel blockers or any ingredients in Cardizem capsules
- are pregnant or are breastfeeding
- have certain types of abnormal heart rhythm like sick sinus syndrome
- have heart problems including, congestive heart failure, left ventricular failure or myocardial infarction with pulmonary congestion
- have hypotension (low blood pressure)
- have kidney or liver disease
- are taking medicines that interact with Cardizem, including: the muscle relaxant dantrolene, the antivirals atazanavir and ritonavir, cimetidine and ranitidine for gastric ulcers or reflux, the immunosuppressant cyclosporine, benzodiazepines like diazepam, midazolam and triazolam for depression or anxiety, corticosteroids like methylprednisolone, beta-blockers like propranolol’ digoxin for heart failure, the antiepileptic carbamazepine, ithium for mood disorders, theophylline for asthma, rimonabant for obesity, alpha-blockers for prostate problems, the antiarrhythmic amiodarone, inhalation anaesthetics like halothane, nitrates for heart conditions, statins for high cholesterol like simvastatin
What medications interact with Cardizem?
Several medications interact with Cardizem capsules 180mg and should either not be taken while you are taking Cardizem 180 or only after discussion and instruction from your doctor:
- Drugs that cause a serious reaction with Cardizem: the muscle relaxant dantrolene; lithium for mood disorders; alpha-blockers for prostate problems; the antiarrhythmic amiodarone; nitrates for heart conditions
- Drugs that affect Cardizem: the antivirals atazanavir and ritonavir; cimetidine and ranitidine for gastric ulcers or reflux; benzodiazepines like diazepam
- Drugs that are affected by Cardizem: the immunosuppressant cyclosporine; benzodiazepines like midazolam and triazolam for depression or anxiety; corticosteroids like methylprednisolone; beta-blockers like propranolol, digoxin for heart failure, the antiepileptic carbamazepine; theophylline for asthma; rimonabant for obesity; inhalation anaesthetics like halothane; statins for high cholesterol like simvastatin
How should Cardizem be taken?
You should take your Cardizem capsules 180mg with a glass of water, swallowed whole, once daily, with or without food. The dose you take and for how long should be as recommended by your doctor. If required your doctor may increase your dose.
How long should you take Cardizem?
You should take your Cardizem capsules 180mg for as long as recommended by your doctor.
Missed dose of Cardizem
If you miss a dose of Cardizem capsules 180mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Cardizem be stored?
You should store your Cardizem capsules 180mg below 25°C in a cool dry place.
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Myloc CR 23.75mg (metoprolol)
Myloc CR general information
What is Myloc CR used for?
Myloc CR tablets 23.75mg are used to treat a variety of conditions of the cardiovascular system including, control of hypertension (high blood pressure) by lowering blood pressure to reduce the risk of complications such as stroke and heart attack; management of angina (chest pain) in patients with heart disease; long-term prevention of myocardial infarction (heart attack); treatment of heart failure to improve survival and quality of life; and control of most forms of arrhythmias and dysrhythmias (irregular heart beat or rhythm) and palpitations. Myloc CR tablets are also used for preventing migraine, and as a supplementary treatment for hyperthyroidism (overactive thyroid). Myloc CR tablets work through a common mechanism in several different body systems to manage the condition and relieve symptoms by reducing heart rate (pulse), workload on the heart (force needed to pump) and oxygen demand by the heart, which increases blood flow and lowers blood pressure.
How does Myloc CR work?
Myloc CR tablets 23.75mg contain metoprolol, which is a beta-blocker or selective beta 1-receptor antagonist and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works via beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are reduced or inhibited by metoprolol in Myloc CR tablets, to slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. Since beta-receptors are found in many tissues, particularly the heart, kidneys, vascular smooth muscle in blood vessel walls, lung, skeletal muscle and liver, all short-term and long-term symptom relief due to taking Myloc CR, is based on blocking beta-receptors in the target tissue. Myloc CR tablets are formulated for controlled release so that metoprolol is that released in a sustained and time controlled manner, to ensure a more even effect over 24 hours, which provides better symptom relief with fewer side effects.
What does Myloc CR contain?
Myloc CR tablets 23.75mg contain the active ingredient metoprolol succinate, a beta-blocker used to treat variety of conditions of the cardiovascular system and other conditions. They also contain ethylcellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, microcrystalline cellulose, paraffin, polyethylene glycol, silicon dioxide, sodium stearyl fumarate, titanium dioxide
What Myloc CR doses are available?
Myloc CR tablets are available to order and buy online from Inhouse Pharmacy in doses of 23.75mg, 47.5mg, 95mg and 190mg.
Treating blood pressure (hypertension) with Myloc CR
Myloc CR tablets 23.75mg contain metoprolol, which is a beta-blocker and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Myloc CR tablets 23.75mg are used to treat high blood pressure (hypertension) by widening blood vessels, reducing heart rate (number of heart beats) and reducing the force of the heart contraction. These actions lower blood pressure and help the heart to cope better, reducing symptoms of breathlessness on exertion and reducing the risk of complications such as stroke and heart attack, due to high blood pressure.
Treating heart disease with Myloc CR
Myloc CR tablets 23.75mg contain metoprolol, which is a beta-blocker and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Myloc CR tablets 23.75mg are used to treat a variety of conditions of the cardiovascular system to improve survival, reduce symptoms and improve the quality of life in patients with heart disease, including, control of hypertension (high blood pressure), management of angina (chest pain); long-term prevention of myocardial infarction (heart attack) and treatment of heart failure.
What are the side effects of Myloc CR?
The mot common side effects reported while taking Myloc CR tablets 23.75mg include: tiredness, dizziness when you change position, cold hands and feet, nausea, vomiting, diarrhoea, stomach pain, constipation, palpitations, weight gain, sleep disturbances or nightmares, shortness of breath on exertion, mood changes or confusion, dry eyes.
When should Myloc CR not be used?
You should not use Myloc CR tablets 23.75mg if you:
- are allergic to metoprolol or any other ingredients in Myloc CR tablets
- have a history of obstructive lung disorder, bronchial asthma or bronchospasm
- are diabetic and taking hypoglycaemic therapy, without discussion with your doctor as metoprolol may prolong the hypoglycaemic response to insulin
- are pregnant or breast feeding, without discussion with your doctor
- have, poor peripheral blood circulation, uncontrolled heart failure, low blood pressure (hypotension),
- have a phaeochromocytoma (a rare tumour of the adrenal gland) which is not already being treated with other medicines
- have certain other heart problems
- are taking medication that may interact with Myloc CR tablets, including: other medicines for high blood pressure; angina or an irregular heart beat such as calcium channel blockers (diltiazem, verapamil, and nifedipine), antiarrhythmics (disopyramide) digoxin, clonidine, hydralazine; other beta-blockers, including eye drops; the antibiotic rifampicin; adrenaline for emergencies like anaphylaxis; monoamine oxidase inhibitors; antiinflammatories like ibuprofen or indomethacin; cimetidine for reflux and ulcers; chlorpromazine for psychiatric disorders.
How should Myloc CR be taken?
You should take your Myloc CR tablets 23.75mg with a glass of water, swallowed whole, with or without food, usually once daily either morning or evening, but at the same time each day. You should take Myloc CR tablets according to your doctor’s recommendations and the number of capsules you take each day, how often you take them and for how long depends on the condition you are being treated for. The dose you are taking may be increased by your doctor. You must take your capsules every day, as instructed and if you are advised to stop taking them, withdrawal should be gradual and treatment should not be discontinued abruptly.
How long should you take Myloc CR?
You should take your Myloc CR tablets 23.75mg for as long as your doctor recommendations, which may be for a few days, weeks, months or longer depending on the condition you are being treated for.
Missed dose of Myloc CR
If you miss a dose of Myloc CR tablets 23.75mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Myloc CR be stored?
You should store your Myloc CR tablets 23.75mg in a cool dry place below 25°C, protected from light and moisture.
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Phenergan 25mg (Promethazine)
Phenergan general information
What is Phenergan used for?
Phenergan tablets 25mg are used to treat a variety of allergic conditions, including allergic contact dermatitis, allergic reactions to drugs, hives (urticaria), and bites and stings, to relieve symptoms of redness, swelling and itching of the skin; also to relieve upper respiratory tract symptoms of allergic rhinitis, including nasal congestion, runny itchy nose and sneezing, caused by seasonal allergies like hayfever. Phenergan tablets 25mg are also used as an antiemetic to reduce nausea and vomiting due to several conditions including postoperative vomiting, irradiation sickness, drug-induced nausea and motion sickness. Phenergan tablets 25mg have sedative properties, which can be used to help with management of the symptoms of measles and chicken pox; also for short-term sedation.
How does Phenergan work?
Phenergan tablets 25mg contain promethazine, an antihistamine belonging to phenothiazine group of drugs that also has antiemetic (prevents nausea) and sedative properties. Histamine is a chemical released from mast cells, (cells involved in allergies) as part of the body’s defence mechanism during an allergic reaction. Histamine and binds to H1 receptors in small blood vessels causing them to leak, allowing white blood cells and blood proteins into the tissues. These infiltrating cells produce inflammatory chemicals (prostaglandins and leukotrienes) that cause tissue swelling and irritation, which are symptoms of an allergic reaction. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors and blocking the action of histamine without blocking its secretion. This action blocks histamine-mediated allergic reactions, relieving symptoms in the upper respiratory tract like nasal congestion, runny itchy nose and sneezing, and in the skin like redness, swelling and itching. Promethazine in Phenergan tablets 25mg also acts on the central nervous system (CNS). Some brain neurones (nerve cells) produce histamine and the action of histamine in the brain is involved in stress and anxiety reactions. Blocking these brain histamine receptors is thought to be responsible for causing sedation. The same CNS mechanism is also responsible for the anti-emetic effect of Phenergan tablets 25mg. Motion sickness is caused by conflicting information being received by the brain from the eyes and the vestibular system in the inner ear; messages sent by the ear suggest motion, whereas the messages sent by the eye suggest that the body is still. The conflicting information received into the brain stimulates the vomiting centre of the brain to induce the vomiting reflex. Promethazine in Phenergan tablets 25mg binds to histamine receptors on cells of the vestibular apparatus of the inner ear and is also thought to bind to histamine receptors on nerve cells in the brain to block the transmission of nerve impulses from the inner ear to the vomiting center in the brain, which in turn prevents transmission of nerve signals from the brain to receptors in the stomach, so that the vomiting reflex is blocked.
What does Phenergan contain?
Phenergan tablets 25mg contain the active ingredient promethazine hydrochloride, an antihistamine belonging to phenothiazine group of drugs that also has antiemetic (prevents nausea) and sedative properties. They also contain lactose, starch maize, povidone, magnesium stearate, hypromellose, macrogol 200, blue opaspray.
Treating allergy with Phenergan
Phenergan tablets 25mg contain the antihistamine promethazine, which is used to relieve symptoms of allergy in several allergic conditions, including allergic contact dermatitis, allergic reactions to drugs, hives (urticaria), bites and stings; also allergic rhinitis caused by seasonal allergies like hayfever. Histamine is a chemical released from mast cells, (cells involved in allergies) as part of the body’s defence mechanism during an allergic reaction and binds to H1 receptors in small blood vessels causing them to leak, allowing white blood cells and blood proteins into the tissues. These infiltrating cells produce inflammatory chemicals (prostaglandins and leukotrienes) that cause tissue swelling and irritation, which are symptoms of an allergic reaction. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors and blocking the action of histamine without blocking its secretion. This action blocks histamine-mediated allergic reactions, relieving symptoms in the upper respiratory tract like nasal congestion, runny itchy nose and sneezing, and in the skin like redness, swelling and itching.
Treating motion sickness with Phenergan
Phenergan tablets 25mg contain promethazine, an antihistamine that is used to control the nausea and vomiting associated with motion sickness caused by all forms of travel including, air, sea train or car travel. The inner ear contains the vestibular apparatus, comprising the membranous labyrinth structures of the cochlea and semicircular canals, where motion or changes in the body’s position is detected and continual information about body position is transmitted to the brain. Motion causes the endolymph (fluid that fills the inner ear) to trigger electrical signals via special sensory cells sending nerve impulses via neurotransmitters (chemicals that allow nerve cells to communicate) along the auditory nerve to the brain to be interpreted. Motion sickness is caused by conflicting information being received by the brain from the eyes and the vestibular system; messages sent by the ear suggest motion, whereas the messages sent by the eye suggest that the body is still. The conflicting information received into the brain stimulates the area postrema or vomiting centre of the brain to induce the vomiting reflex. Promethazine in Phenergan tablets 25mg binds to histamine receptors on cells of the vestibular apparatus of the inner ear and is also thought to bind to histamine receptors on nerve cells in the brain and this blocks the transmission of nerve impulses from the inner ear to the vomiting center in the brain, which in turn prevents transmission of nerve signals from the brain to receptors in the stomach, so that the vomiting reflex is blocked. Phenergan tablets 25mg are also used to reduce nausea and vomiting due to several conditions including postoperative vomiting, irradiation sickness and drug-induced nausea.
Phenergan for sedation
Phenergan tablets 25mg contain promethazine, an antihistamine that has sedating properties. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors in various parts of the body including the brain. Some brain neurones (nerve cells) produce histamine and the action of histamine in the brain is involved in stress and anxiety reactions. Blocking these brain histamine receptors is thought to be responsible for causing sedation.
What are the side effects of Phenergan?
The most commonly reported side effects when taking Phenergan tablets 25mg include: dry mouth, gastro-intestinal disturbances (diarrhoea, constipation, nausea, vomiting or abdominal pain) loss of appetite, tiredness, sleepiness, restlessness, dizziness, blurred vision.
When should Phenergan not be used?
You should not use Phenergan tablets 25mg if you:
- are allergic to promethazine or any ingredients in Phenergan
- are allergic to sulphites, benzoates or phenothiazines
- are pregnant or are breastfeeding
- have had jaundice induced by other phenothiazine derivatives
- are taking medicines that interact with Phenergan, including: monoamine oxidase inhibitors (MAOIs) (up to 14 days previously), tricyclic antidepressants, sedatives and hypnotics, opioid analgesics, barbiturates
Phenergan tablets 25mg should not be used for children under 2 years or for anyone in a coma.
What medications interact with Phenergan?
Several medications interact with Phenergan tablets 25mg to increase side effects and can cause a serious reaction and should either not be taken while you are taking Phenergan or only after discussion and instruction from your doctor: including: monoamine oxidase inhibitors (MAOIs) (up to 14 days previously, tricyclic antidepressants, sedatives and hypnotics, opioid analgesics, barbiturates.
How should Phenergan be taken?
You should take your Phenergan tablets 25mg swallowed whole with a glass of water. The dose you take and how often depends on what you are being treated for and your doctor’s recommendation. For allergy and sedation you should take your Phenergan tablets 25mg at night. For travel sickness you should take one tablet the night before travel and you can take another dose the next day, provided 6-8 hours has elapsed. For nausea and vomiting you should take your Phenergan tablets 25mg every 4 to 6 hours as recommended by your doctor. You should continue to take your Phenergan tablets 25mg for as long as your symptoms persist, or as recommended by your doctor but for no longer than 10 consecutive days.
How long should you take Phenergan?
You should continue to take your Phenergan tablets 25mg for as long as your symptoms persist, or as recommended by your doctor but for no longer than 10 consecutive days.
Missed dose of Phenergan
If you miss a dose of Phenergan tablets 25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Phenergan be stored?
You should store your Phenergan below 25°C in a cool dry place.
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Cardizem CD 240mg (Diltiazem)
Cardizem general information
What is Cardizem used for?
Cardizem capsules 240mg are used to treat hypertension, which is high blood pressure when at rest. Although there are usually no other symptoms, high blood pressure increases risk of cardiovascular disease. Cardizem CD capsules reduce the risk of stroke and heart attack, by lowering blood pressure to normal resting levels. Cardizem CD can be used alone or in combination with other antihypertensive medications such as diuretics. Cardizem capsules 240mg are also used to treat chronic stable angina, to prevent symptoms like chest pain and to prevent heart attack; also to treat angina due to coronary artery spasm, which is an acute angina attack which can occur at rest.
How does Cardizem work?
Cardizem capsules 240mg contain diltiazem, which is a calcium channel blocker that inhibits the inflow of calcium ions across specific calcium channels in the cell membrane into smooth muscle cells of the heart (myocardium) and blood vessel walls (only arteries). Calcium is needed for smooth muscle cells to contract, so by blocking calcium channels, smooth muscle cells contraction is prevented. Diltiazem in Cardizem capsules 240mg blocks calcium channels in smooth muscle cells, allowing peripheral arteries to relax and widen (vasodilation) and this reduces the workload on the heart, the force needed for the heart to pump blood around the body (negative inotropic effect), increases oxygen supply to the heart, and decreases blood pressure. Cardizem capsules CD also causes widening of the main arteries of the heart, increasing the oxygen supply to the heart and, as the heart workload is reduced, the demand for oxygen is also reduced, which prevents chest pain symptoms of angina caused by lack of oxygen to the heart muscle.
What does Cardizem contain?
Cardizem capsules 240mg contain the active ingredient diltiazem hydrochloride, a calcium channel blocker used to treat hypertension and angina, formulated for slow release over a 24 hours period. They also contain fumaric acid, purified talc, non-pareil seeds (sucrose), colloidal silica, white beeswax, ethylcellulose, castor oil, stearic acid, methacrylic acid copolymers, tributyl acetylcitrate, simethicone, gelatin, Brilliant Blue FCF CI 42090 and titanium dioxide.
What doses of Cardizem are available?
Cardizem CD capsules are available online form Inhouse Pharmacy in 3 doses:
- 120mg CDcapsule
- 180mg CD capsules
- 240mg CD capsules
Treating hypertension (high blood pressure) with Cardizem
Cardizem capsules 240mg contain diltiazem, a calcium channel blocker used to lower blood pressure in people with hypertension (high blood pressure at rest), who are at risk of cardiovascular disease due to high blood pressure, although there are usually no other symptoms. Cardizem capsules 240mg can either be used alone or in combination with other antihypertensive drugs such as diuretics. Diltiazem in Cardizem CD capsules 240mg blocks the inflow of calcium ions, needed for contraction, into smooth muscle cells of the heart and blood vessel walls (only arteries), which causes blood vessel walls to relax and peripheral arteries to widen. This action reduces the workload on the heart, which is the force needed for the heart to pump blood around the body, as measured by blood pressure. By lowering blood pressure Cardizem capsules 240mg help reduce risk of cardiovascular disease including stroke and heart attack.
Treating angina with Cardizem
Cardizem capsules 240mg contain diltiazem, a calcium channel blocker used to treat chronic stable angina and angina due to coronary artery spasm, which is an acute angina attack that can occur at rest. Diltiazem in Cardizem CD capsules 240mg blocks the inflow of calcium ions, needed for contraction, into smooth muscle cells of the heart and blood vessel walls (only arteries), which causes blood vessel walls to relax and peripheral arteries to widen. Cardizem capsules 240mg reduces the workload on the heart and its demand for oxygen, while at the same time increasing oxygen supply to the heart, which prevents chest pain symptoms of angina caused by lack of oxygen to the heart muscle.
What are the side effects of Cardizem?
The most commonly reported side effects when taking Cardizem capsules 240mg include: headache, dizziness, flushing, bradycardia (slow heart rate), gastrointestinal upset (nausea, vomiting, constipation, diarrhoea, indigestion, gastric pain) oedema (swelling of the ankles, feet, face or hands), flushing, palpitations, tiredness, weakness, drowsiness.
When should Cardizem not be used?
You should not use Cardizem capsules 240mg if you:
- are allergic to diltiazem, other calcium channel blockers or any ingredients in Cardizem capsules
- are pregnant or are breastfeeding
- have certain types of abnormal heart rhythm like sick sinus syndrome
- have heart problems including, congestive heart failure, left ventricular failure or myocardial infarction with pulmonary congestion
- have hypotension (low blood pressure)
- have kidney or liver disease
- are taking medicines that interact with Cardizem, including: the muscle relaxant dantrolene, the antivirals atazanavir and ritonavir, cimetidine and ranitidine for gastric ulcers or reflux, the immunosuppressant cyclosporine, benzodiazepines like diazepam, midazolam and triazolam for depression or anxiety, corticosteroids like methylprednisolone, beta-blockers like propranolol’ digoxin for heart failure, the antiepileptic carbamazepine, ithium for mood disorders, theophylline for asthma, rimonabant for obesity, alpha-blockers for prostate problems, the antiarrhythmic amiodarone, inhalation anaesthetics like halothane, nitrates for heart conditions, statins for high cholesterol like simvastatin
What medications interact with Cardizem?
Several medications interact with Cardizem capsules 240mg and should either not be taken while you are taking Cardizem 240 or only after discussion and instruction from your doctor:
- Drugs that cause a serious reaction with Cardizem: the muscle relaxant dantrolene; lithium for mood disorders; alpha-blockers for prostate problems; the antiarrhythmic amiodarone; nitrates for heart conditions
- Drugs that affect Cardizem: the antivirals atazanavir and ritonavir; cimetidine and ranitidine for gastric ulcers or reflux; benzodiazepines like diazepam
- Drugs that are affected by Cardizem: the immunosuppressant cyclosporine; benzodiazepines like midazolam and triazolam for depression or anxiety; corticosteroids like methylprednisolone; beta-blockers like propranolol, digoxin for heart failure, the antiepileptic carbamazepine; theophylline for asthma; rimonabant for obesity; inhalation anaesthetics like halothane; statins for high cholesterol like simvastatin
How should Cardizem be taken?
You should take your Cardizem capsules 240mg with a glass of water, swallowed whole, once daily, with or without food. The dose you take and for how long should be as recommended by your doctor. If required your doctor may increase your dose.
How long should you take Cardizem?
You should take your Cardizem capsules 240mg for as long as recommended by your doctor.
Missed dose of Cardizem
If you miss a dose of Cardizem capsules 240mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Cardizem be stored?
You should store your Cardizem capsules 240mg below 25°C in a cool dry place.
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Kenozole Cream (Ketoconazole)
Kenozole general information
What is Kenozole used for?
Kenozole Cream 2% is used as a topical treatment for fungal infections of the skin and scalp, due to the Tinea fungus. Tinea is a dermatophyte fungus also known as ringworm. Tinea causes fungal infection in different parts of the body including ringworm of the foot, also known as Athlete's foot (tinea pedis), of the body (tinea corporis), of the groin (tinea cruris or jock itch), and of the scalp (tinea capitis). Kenozole Cream 2% is also used to treat infection by the yeast fungus Malassezia, which causes Pityriasis versicolor, characterised by flaky discoloured patches that appear on the chest and back and seborrhoeic dermatitis, a form of dermatitis or inflammation of the skin that affects mainly the scalp and face. Kenozole Cream 2% is also effective against infection with the yeast fungus Candida, which causes cutaneous candidiasis, characterised by itchy red rash on various parts of the body, usually in warm, moist creased areas of skin, like under the arms and in the groin.
How does Kenozole work?
Kenozole Cream 2% contains ketoconazole, a synthetic broad-spectrum antifungal that is used to treat a variety of fungal infections of the skin. Ketoconazole in Kenozole Cream 2% prevents growth of dermatophyte and yeast fungi by inhibiting the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells. This results in altering the permeability of the fungal cell membrane causing it to become weakened, so that the cell contents to leak out, which kills the fungus, preventing the infection from spreading and relieving symptoms caused by the fungal infection, including pain and inflammation. When used as a topical antifungal, no detectable ketoconazole enters the blood, reducing risk of systemic side effects.
What does Kenozole contain?
Kenozole Cream contains the active ingredient ketoconazole 2% (w/w), a synthetic broad-spectrum antifungal that is used to treat a variety of fungal infections.
Treating fungal infections with Kenozole
Kenozole Cream 2% contains ketoconazole, a synthetic broad-spectrum antifungal that is used to treat a variety of fungal infections due to dermatophyte fungus Tinea, known as ringworm and the yeast Candida. These infections include, ringworm of the foot, also known as Athlete's foot (tinea pedis), of the body (tinea corporis), of the groin (tinea cruris or jock itch), and of the scalp (tinea capitis). Malassezia is a yeast-like fungus that causes Pityriasis versicolor, characterised by flaky discoloured patches that appear on the chest and back and seborrhoeic dermatitis, a form of dermatitis or inflammation of the skin that affects mainly the scalp and face. Candida causes cutaneous candidiasis, characterised by itchy red rash on various parts of the body, usually in warm, moist creased areas of skin, like under the arms and in the groin. Ketoconazole in Kenozole Cream 2% prevents growth of dermatophyte and yeast fungi by inhibiting the synthesis of ergosterol, an important component of fungal cell membrane that is not found in animal cells. This results in altering the permeability of the fungal cell membrane causing it to become weakened, so that the cell contents to leak out, which kills the fungus, preventing the infection from spreading and relieving symptoms caused by the fungal infection, including pain and inflammation.
What are the side effects of Kenozole?
The most commonly reported side effects when using Kenozole Cream 2% include, burning sensation or irritation at the site of application, such as redness, pain and swelling; oily or dry scalp, mild hair loss.
When should Kenozole not be used?
You should not use Kenozole Cream 2% if you:
- are allergic to ketoconazole or any ingredients in Kenozole
- are pregnant or are breastfeeding, without discussion with your doctor
How should Kenozole be used?
You should apply your Kenozole Cream 2% to the affected area and rub gently into the skin once or twice daily depending on what you are being treated for and the severity of the infection. You should continue your course of treatment with Kenozole Cream for 2-6 weeks, depending on what you are being treated for and your doctor’s recommendation, until signs and symptoms of the infection has disappeared. Wash your hands to prevent spreading the infection and do not get the cream into your eyes.
How long should you take Kenozole?
You should continue your course of treatment with Kenozole Cream for 2-6 weeks, depending on what you are being treated for and your doctor’s recommendation.
Missed dose of Kenozole
If you miss a dose of Kenozole apply it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.
How should Kenozole be stored?
You should store your Kenozole below 25°C in a cool dry place.
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