Your Country: ?
Your Currency: ?
CONTACT US
USA: 877 271 6591
UK: 0808 234 7254
Outside UK/USA: 1 877 271 6591
Your Country: ?
Your Currency: ?
Login | SHOPPING CART    (0 items)
USA: 877 271 6591
UK: 0808 234 7254
Outside UK/USA: 1 877 271 6591
Your Country: ?
Your Currency: ?
Login | SHOPPING CART    (0 items)
FREE SHIPPING TO UNITED STATES

                Ooops, sorry the page you requested cannot be found.

               
Are you looking for:
Avigra (Sildenafil 100mg) 4's

Avigra general information

What is Avigra used for?

Avigra tablets 100mg are used to treat erectile dysfunction (impotence) in men, which is inability to achieve or maintain a hard erect penis suitable for sexual activity, due to insufficient blood flow into the penis. Avigra tablets 100mg relax the blood vessels in the penis increasing blood flow and causing an erection, which is the natural response to sexual stimulation. However, Avigra 100 will only work if you are sexually aroused.

How does Avigra work?

Avigra tablets 100mg contain sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor that acts on the erectile tissue of the penis to increase blood flow, which is needed to cause an erection. During sexual stimulation nitric oxide is released in the erectile tissue of the penis which activates the enzyme guanylate cyclase. This enzyme increases levels of a chemical called cyclic guanosine monophosphate (cGMP), which relaxes the blood vessels in the penis and allows blood to fill the spongy erectile tissues to cause an erection. Another enzyme called phosphodiesterase type 5 (PDE5) breaks down cGMP preventing blood flow into the penis, which causes loss of an erection. Avigra tablets 100mg inhibit the action of PDE5 which resolves erectile dysfunction by allowing the natural process of sexual stimulation to activate the cGMP mechanism for achieving and maintaining an erection.

How long does Avigra last?

Avigra tablets 100mg should be taken within an hour of planned sex and in most cases it helps you to get an erection in about 30 minutes that will last for around 4 hours, provided you are sexually excited. Avigra 100 does not work if you are not aroused.

What does Avigra contain?

Avigra tablets 100mg contain the active ingredient sildenafil which resolves erectile dysfunction (impotence) in men, by increasing blood flow into the penis. They also contain microcrystalline cellulose, calcium hydrogen phosphate anhydrous, croscarmellose sodium, magnesium stearate, hypromellose, titanium dioxide, lactose, glycerol triacetate, indigo carmine aluminium lake (CI 73015), and PF0102.

Treating erectile dysfunction (impotence) with Avigra

Avigra tablets 100mg contain sildenafil, a phosphodiesterase type 5 (PDE5) inhibitor that is used to treat erectile dysfunction (impotence). When taken before planned sexual activity, Avigra 100 inhibits the breakdown (by the enzyme PDE5) of a chemical called cGMP, produced in the erectile tissue of the penis during sexual arousal, and this action allows blood flow into the penis causing an erection.

What are the side effects of Avigra?

The most commonly reported side effects when taking Avigra include: headache, dizziness, flushing, indigestion, nasal congestion, diarrhoea, rash. More serious side effects include unusual heartbeat, urinary tract infection (stinging or burning urine, more frequent need to pass urine), blood in the urine, changes in vision such as blurring, a blue colour to your vision or a greater awareness of light, persistent headache or fainting, bleeding from the nose.

When should Avigra not be used?

You should not use Avigra if you:
  • are allergic to sildenafil or any other ingredients in Avigra 100mg tablets
  • are taking any nitrate medication, such as nitroglycerin for angina, as it may lead to a severe drop in blood pressure
  • have a condition where sexual intercourse inadvisable due to cardiovascular or heart problems or you have had a heart attack or stroke in the last 6 months
  • have liver disease
  • have abnormally high or low blood pressure
  • have an eye disease like non-arteritic anterior ischaemic optic neuropathy (NAION), which causes loss of vision or if you have retinitis pigmentosa
  • are taking medication that may interact with Avigra or may increase your risk for side-effects, including cimetidine for treating ulcers, antibiotics like erythromycin and rifampicin, verapamil or diltiazem (for high blood pressure), ritonavir or saquinavir (for HIV), the antifungals itraconazole or ketoconazole, alpha-blockers like amlodipine for high blood pressure.

What medications interact with Avigra?

Several medications interact with Avigra and should either not be taken while you are taking Avigra or only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction with Avigra: any nitrate medication, such as nitroglycerin for angina
  • Drugs that affect Avigra: cimetidine for treating ulcers, antibiotics like erythromycin and rifampicin, the antifungals itraconazole or ketoconazole, ritonavir or saquinavir for HIV
  • Drugs that are affected by Avigra: alpha-blockers like amlodipine for high blood pressure

How should Avigra be taken?

You should take your Avigra tablet 100mg with a glass of water approximately one hour before sexual activity and without food. If you have a large meal before taking your Avigra 100mg tablet it may take longer to work. You should take no more than one tablet a day and only if you plan to have sex.

Missed dose of Avigra

You should only take an Avigra 100mg tablet when you plan to have sex; it is not intended as a regular medication.

How should Avigra be stored?

You should store your Avigra below 25°C in a cool dry place.


Spiractin 25 (Spironolactone)

Spiractin general information

What is Spiractin used for?

Spiractin tablets 25mg are used to reduce fluid retention and swelling (oedema) which is caused by several conditions, including congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease.  Spiractin 25 can be used alone to treat hypertension or in combination with other antihypertensive medications like beta blockers, to enhance their activity.  Spiractin tablets 25mg is also used to increase blood potassium levels, which occurs in a condition called hypokalaemia (low blood potassium) and to treat hyperaldosteronism, which is caused by excess secretion by the adrenal gland of the hormone aldosterone (involved in regulating sodium and potassium levels), both of which can cause fluid retention.  Spiractin 25 has anti-androgen activity which is used in the treatment of female hirsutism (androgen-related increase in facial and body hair) and can be used as an anti-androgen component of transgender hormone therapy, to help stimulate the development of female sexual characteristics for male to female transsexuals.    

How does Spiractin work?

Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic (water pill) that acts as an antagonist of the hormone aldosterone, by binding to the aldosterone receptor blocking its action.  This action of spironolactone in Spiractin tablets 25mg increases sodium excretion and reduces potassium loss at the distal renal tubule of the kidney.  The overall effect of this action is to increase water excretion in the urine which reduces fluid build-up in the tissues, increase blood potassium levels and lower sblood pressure.  Spironolactone in Spiractin tablets 25mg also has moderate anti-androgenic activity as it binds to the androgen receptor competing with dihydrotestosterone (DHT) an active metabolite of testosterone.  Binding of DHT to the androgen receptor promotes male characteristics therefore, blocking the action of DHT helps reduce male characteristics.  Another anti-androgenic action of Spiractin 25 is that it blocks the synthesis of a testosterone by the ovaries. 

What does Spiractin contain?

Spiractin tablets 25mg contain the active ingredient spironolactone, a potassium-sparing diuretic used to treat oedema in various conditions.  They also contain quinoline yellow, sunset yellow, erythrosine, polysorbate, peppermint oil, povidone, microcrystalline cellulose, maize starch, sodium starch glycollate, talc, magnesium stearate and lactose.

Treating oedema with Spiractin

Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic (water pill) that is used to treat fluid retention (oedema) caused by several conditions, including congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease.  Spironolactone in Spiractin tablets 25mg works by blocking the action of the hormone aldosterone on the kidneys, which increases excretion of excess water and sodium from the body while at the same time maintaining blood potassium levels. 

Spiractin for hypertension

Spiractin tablets 25mg contain spironolactone, a potassium-sparing diuretic that is used to treat hypertension or high blood pressure, which increases risk of cardiovascular disease and if uncontrolled can cause kidney damage, stroke, heart attack and heart failure.  Spironolactone in Spiractin tablets 25mg binds to the receptor for the hormone aldosterone on the kidneys, blocking the action of aldosterone, which increases sodium excretion and reduces potassium loss at the distal renal tubule of the kidney.  This action of spironolactone in Spiractin tablets 25mg increases water excretion in the urine which reduces fluid build-up in the tissues, increase blood potassium levels and lowers blood pressure. 

Spiractin for transgender treatment

Spiractin tablets 25mg contain spironolactone, which is primarily used as a diuretic, to reduce fluid retention in conditions such as congestive heart failure, hypertension (high blood pressure), liver cirrhosis and kidney disease.  Spironolactone in Spiractin tablets 25mg also acts as an anti-androgen by binding to the androgen receptor and competing with dihydrotestosterone (DHT), the active metabolite of testosterone, which promotes male characteristics, thereby blocking the action of DHT.  Using an anti-androgen like spironolactone (usually in high doses of 200–400 mg per day) allows the amount of oestrogen administered for feminising hormone therapy to be reduced while optimising the hormone regime needed to stimulate breast development, feminisation of skin, and female fat distribution. 

What are the side effects of Spiractin?

The most commonly reported side effects when taking Spiractin includes nausea, vomiting, headache, abdominal cramps and pain, diarrhoea, headache, drowsiness, lethargy, hair loss and excessive hair growth.  Other side effects include skin rash, menstrual period changes in women, breast enlargement (gynaecomastia) and sexual problems (impotence) in men.

When should Spiractin not be used?

You should not use Spiractin tablets 25mg if you:

  • are allergic to spironolactone or any ingredients in Spiractin
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • have high potassium levels in your blood due to a potassium rich diet or if you are taking medications or supplements that increase blood potassium levels
  • are not producing or passing urine
  • are taking other medications that may interact with Spiractin, such as potassium supplements, non-steroidal anti-inflammatory drugs like indomethacin or mefenamic acid, aspirin, digoxin for heart failure, carbenoxolone for mouth ulcers, other diuretics, the ACE inhibitors antihypertensives, ammonium chloride in some cough medications, cholestyramine for lowering blood cholesterol

What medications interact with Spiractin?

Several medications interact with Spiractin tablets 25mg and should either not be taken while you are taking Spiractin or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with Spiractin: potassium supplements, ammonium chloride in some cough medications, cholestyramine for lowering blood cholesterol, the ACE inhibitors antihypertensives
  • Drugs that affect Spiractin: non-steroidal anti-inflammatory drugs like indomethacin or mefenamic acid and aspirin, carbenoxolone for mouth ulcers
  • Drugs that are affected by Spiractin: digoxin for heart failure

How should Spiractin be taken?

You should take your Spiractin tablets 25mg with a glass of water with or without food, once or twice daily.  The dose you take depends on your condition and what you are being treated for and should be as recommended by your doctor.  You should continue taking your Spiractin tablets 25mg even if you are feeling well, which may be for a few days or several weeks and your doctor may increase your dose during treatment. 

How long should you take Spiractin?

You should continue taking your Spiractin tablets 25mg even if you are feeling well, which may be for a few days or several weeks and your doctor may increase your dose during treatment. 

Missed dose of Spiractin

If you miss a dose of Spiractin tablets 25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Spiractin be stored?

You should store your Spiractin tablets 25mg below 30°C in a cool dry place. 

 

 

Naprosyn SR 1000mg (Naproxen)

Naprosyn general information

What is Naprosyn used for?

Naprosyn tablets 1000mg are used to treat chronic inflammatory diseases, including rheumatoid arthritis, juvenile rheumatoid arthritis, osteoarthritis (wear and tear) and ankylosing spondylitis, (an autoimmune inflammatory disease that affects the joints in the spine and pelvis and can cause fusion of the spine) to reduce pain, inflammation, tenderness, stiffness and swelling in the affected joints. Naprosyn tablets 1000mg do not cure arthritic disease but can relieve symptoms of pain and inflammation and improve the functional use of affected joints. Naprosyn tablets 1000mg are also used for musculoskeletal disorders, such as sprains, strains, lower back pain (lumbago) to relieve chronic pain and inflammation. Naprosyn 1000 is not suitable for short-term treatment of acute pain.

How does Naprosyn work?

Naprosyn tablets 1000mg contain naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that has anti-inflammatory, analgesic (pain relieving) and anti-pyretic properties (reduces fever). Naproxen in Naprosyn tablets 1000mg blocks the production of specific chemicals called prostaglandins (PG) that mediate inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) including cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins. Inhibition of COX-2 helps relieve the symptoms of inflammation, including pain, swelling, and joint stiffness. Inhibition of COX-1 is responsible for the gastrointestinal side effects that are due to inhibition of protective prostaglandins in the gut and disruption of regulation of acid content. Naprosyn tablets 1000mg are formulated for sustained controlled release, which provides a constant concentration of naproxen over a period of time, for maximum effectiveness and minimum side effects.

What does Naprosyn contain?

Naprosyn tablets 1000mg contain the active ingredient naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve joint pain and inflammation in arthritis and other conditions. They also contain hydroxypropyl methyl cellulose, sunset yellow FCF, purified water.

Treating arthritis with Naprosyn

Naprosyn tablets 1000mg contain the active ingredient naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation in joints affected with arthritis. Osteoarthritis (also known as wear and tear and is a degenerative disease) and rheumatoid arthritis (an autoimmune disease where the immune system turns on self) are chronic inflammatory diseases in which the joints become inflamed, swollen and painful. Naproxen in Naprosyn tablets 1000mg blocks the production of specific chemicals called prostaglandins (PG) that mediate inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) including cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins. Inhibition of COX-2 helps relieve the symptoms of inflammation, including pain, swelling, and joint stiffness, to improve the functional use of affected joints.

Naprosyn for pain and inflammation

Naprosyn tablets 1000mg contain naproxen, a nonsteroidal anti-inflammatory drug (NSAID) that has anti-inflammatory, analgesic (pain relieving) and anti-pyretic properties (reduces fever). Several chronic inflammatory joint diseases cause pain and inflammation, including rheumatoid arthritis (in adults and children), osteoarthritis (wear and tear) and ankylosing spondylitis, (an autoimmune inflammatory disease that affects the joints in the spine and pelvis and can cause fusion of the spine). Naproxen in Naprosyn tablets 1000mg blocks the production of specific chemicals called prostaglandins (PG) that mediate inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) including cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins. Inhibition of COX-2 helps relieve the symptoms of inflammation, including pain, swelling, and joint stiffness. Naprosyn tablets 1000mg also inhibit cyclooxygenase 1 (COX-1), which is thought to be responsible for the gastrointestinal side effects associated with the non-selective NSAIDs. Naprosyn tablets 1000mg are formulated for sustained controlled release, which provides a constant concentration of naproxen over a period of time, for maximum effectiveness and minimum side effects, but are not suitable for acute pain.

What are the side effects of Naprosyn?

The most commonly reported side effects when taking Naprosyn tablets 1000mg are gastrointestinal and include: upset stomach or stomach pain, diarrhoea, indigestion, bloating wind, heartburn, indigestion, constipation. Other side effects include: dizziness, drowsiness, headache, light-headedness, vertigo, tinnitus (buzzing or ringing in the ears), oedema and fluid retention, thirst, skin eruptions including rash, itching, sweating.

What are the health risks when taking Naprosyn?

Naprosyn tablets 1000mg have been associated with increased risk of gastric ulceration and bleeding and cardiovascular events including heart attack, although these events are rare.

When should Naprosyn not be used?

You should not use Naprosyn tablets 1000mg if you:
  • are allergic to naproxen or any other NSAID including aspirin, or any ingredients in Naprosyn
  • have aspirin-induced asthma or rhinitis (runny itchy nose)
  • have asthma
  • have uncontrolled hypertension, severe heart failure or cardiovascular disease, without discussion with your doctor
  • have active or a history of gastrointestinal bleeding or perforation due to an ulcer
  • have a tendency to bleed easily
  • are pregnant attempting to become pregnant or are breastfeeding, without discussion with your doctor
  • have kidney or liver disease
  • are taking medicines that interact with Naprosyn, including: aspirin or other NSAIDs, anticoagulants like warfarin, cholestyramine for high cholesterol, probenecid for gout, the anti-cancer drug methotrexate, lithium for mood disorders, diuretics like frusemide, beta blockers and ACE inhibitors for high blood pressure, digitalis for heart failure, sulphonamide antibiotics, sulphonylureas for diabetes, SSRI antidepressants, corticosteroids,

What medications interact with Naprosyn?

Several medications interact with Naprosyn tablets 1000mg and should either not be taken while you are taking Naprosyn or only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction or increase side effects with Naprosyn: aspirin or other NSAIDs, SSRI antidepressants, anticoagulants like warfarin, and ACE inhibitors
  • Drugs that affect Naprosyn: cholestyramine for high cholesterol, probenecid for gout
  • Drugs that are affected by Naprosyn: anticoagulants like warfarin, the anti-cancer drug methotrexate, lithium for mood disorders, diuretics like frusemide, beta blockers and ACE inhibitors for high blood pressure, sulphonamide antibiotics, sulphonylureas for diabetes

How should Naprosyn be taken?

You should take your Naprosyn tablets 1000mg swallowed whole with a glass of water once daily with or without food, preferably after a meal to reduce risk of gastrointestinal side effects and at the same time each day. The dose you take and how often depends on what you are being treated for and your doctor’s recommendation. You should continue to take your Naprosyn tablets 1000mg for as long as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for, any side effects and how well you respond.

How long should you take Naprosyn?

You should continue to take your Naprosyn tablets 1000mg for as long as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for, any side effects and how well you respond.

Missed dose of Naprosyn

If you miss a dose of Naprosyn tablets 1000mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Naprosyn be stored?

You should store your Naprosyn below 30°C in a cool dry place and protect from light.


Cardace 10mg (Ramipril) 150s

Cardace general information

What is Cardace used for?

Cardace tablets 10mg (also known as Altace) are used to treat mild to moderate essential hypertension, which is high blood pressure when at rest, by lowering blood pressure to normal resting levels. This reduces risk of stroke, heart attack and end organ damage such as kidney disease. Cardace 10 is also used to treat congestive heart failure, by helping weakened heart muscles pump more efficiently and reducing feelings of breathlessness on exertion. Cardace tablets 10mg are also used to reduce risk of cardiovascular disease in patients over 55 years who have a history of heart attack, coronary artery disease, stroke or peripheral vascular disease, or reduce need for surgery to replace damaged blood vessels; also in people with diabetes who also have other risk factors like high cholesterol or high blood pressure or who smoke. Cardace 10 can be used on its own or with a diuretic, which helps get rid of excess water that is retained in body tissues and can cause swelling (oedema).

How does Cardace work?

Cardace tablets 10mg (also known as Altace) contain ramipril, which is a prodrug that is converted in the liver to its active form ramiprilat, a potent and long acting Angiotensin Converting Enzyme (ACE) inhibitor. Ramipril in Cardace 10 prevents the formation of angiotensin II, a hormone that has several actions involved in regulating blood pressure, which is the force needed to pump blood around the body. Angiotensin II causes salt and water retention by the kidneys, and causes blood vessels to constrict (narrow); this increases blood volume while at the same time reducing blood vessel volume, which increases blood pressure. Ramipril in Cardace 10 inhibits the conversion of angiotensin II from angiotensin I, which allows blood vessels to relax and widen, reducing the force needed by the heart to pump blood around the body, reducing its workload and lowering blood pressure.

What does Cardace contain?

Cardace tablets 10mg contain the active ingredient ramipril an Angiotensin Converting Enzyme (ACE) inhibitor, which widens blood vessels and lowers blood pressure.

Treating hypertension (high blood pressure) with Cardace

Cardace tablets 10mg contain ramipril, an Angiotensin Converting Enzyme (ACE) that is used to treat hypertension, which is high blood pressure when at rest, in people with high blood pressure who are at increased risk of cardiovascular disease, including stroke and heart attack. Ramipril in Cardace 10 inhibits the formation of angiotensin II, a hormone that has several actions involved in regulating blood pressure, which is the force needed to pump blood around the body. Cardace tablets 10mg relax and widen blood vessels, reducing the force needed by the heart to pump blood around the body, reducing its workload and lowering blood pressure.

Cardace for treating congestive heart failure

Cardace tablets 10mg contain ramipril, an Angiotensin Converting Enzyme (ACE) that is used to widen blood vessels and reduce the force needed for the heart to pump blood around the body. This helps weakened heart muscle, such as in congestive heart failure, to work more efficiently and reduces symptoms of breathlessness on exertion. You may also be prescribed a diuretic to help get rid of excess water that is retained in your body tissues and can cause swelling (oedema), as a result of congestive heart failure.

What are the side effects of Cardace?

The most commonly reported side effects when taking Cardace tablets 10mg include: dizziness, light-headedness, headache, fatigue, sleepiness, skin rash, nausea, cough.

When should Cardace not be used?

You should not use Cardace tablets 10mg if you:
  • are allergic to ramipril or any ingredients in Cardace 10
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • have diabetes, or have had angioedema (rapid swelling under the skin)
  • have mitral stenosis, which is heart problems affecting the flow of blood away from the heart.
  • are taking potassium tablets or potassium-containing salt substitutes
  • are taking medicines that interact with Cardace 10, including: other antihypertensive medications, potassium-sparing diuretics like spironolactone, non steroidal antiinflammatories (NSAID) like diclofenac, insulin and some diabetic medication like glyburide, lithium for mood disorders

What medications interact with Cardace?

Several medications interact with Cardace tablets 10mg and should either not be taken while you are taking Cardace or only after discussion and instruction from your doctor:
  • Drugs that cause a serious reaction with Cardace: other antihypertensive medications can cause blood pressure to fall too low (hypotension), potassium-sparing diuretics like spironolactone
  • Drugs that affect Cardace: non steroidal antiinflammatories (NSAID) like diclofenac and aspirin
  • Drugs that are affected by Cardace: and insulin and some diabetic medication like glyburide, lithium for mood disorders

How should Cardace be taken?

You should take your Cardace tablets 10mg with a glass of water, with or without food, once daily, depending on your doctor’s recommendations. Your doctor may increase your dose depending on what you are being treated for and your condition. Cardace tablets 10mg helps improve your condition but does not cure it, therefore, you should continue to take your Cardace 10 for as long as your doctor recommends. Cardace 10 may take a few weeks to lower blood pressure and you should keep taking your tablets even if you feel well, as often there are no symptoms for high blood pressure.

How long should you take Cardace?

Cardace tablets 10mg helps improve your condition but does not cure it therefore you should continue to take your Cardace 10 for as long as your doctor recommends. Cardace 10 may take a few weeks to lower blood pressure and you should keep taking your tablets even if you feel well, as often there are no symptoms for high blood pressure.

Missed dose of Cardace

If you miss a dose of Cardace tablets 10mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Cardace be stored?

You should store your Cardace tablets 10mg below 25°C in a cool dry place.



Tazorac Gel (Tazarotene 0.1%)

Tazorac Gel general information

What is Tazorac Gel used for?

Tazorac Gel 0.1% is a topical medication used to moderate to severe facial acne vulgaris, to prevent the formation and spread of pimples (papules), spots or whiteheads (pustules) and blackheads (comedones), helping to clear up these skin blemishes as well as preventing the outbreak of new acne. Tazorac Gel is also used to treat stable plaque psoriasis or psoriasis vulgaris where there is up to 20% body surface area involvement. Psoriasis is a common non-allergic, chronic skin condition that causes the appearance of red raised patches of skin covered in a dry silvery scaly rash usually on the skin of the elbows, knees and lower back. Psoriasis is thought to be an autoimmune disorder (when the immune system attacks self), which affects people of any age, usually who have a genetic predisposition. Tazorac Gel helps reduce the redness and scaly appearance of the affected skin and relieve the symptoms of psoriasis, which are mainly pain and itching.

How does Tazorac Gel work?

Tazorac Gel 0.1% contains tazarotene, a retinoid prodrug of tazarotenic acid, which binds to the receptor for retinoic acid, a metabolite of vitamin A (retinol) that is important for growth and development and can affect the way skin cells behave. Tazarotene in Tazorac Gel is thought to act as a keratolytic by blocking the hardening processes of the outer skin layer (keratinisation and cornification) and increasing the shedding of old hardened skin cells, while at the same time preventing epidermal hyperproliferation, which is excessive growth of the upper layer of skin cells or keratinocytes. It is also thought to have anti-inflammatory properties. The combined effect of these actions is to help restore normal cell growth and behaviour to the keratinocytes, which helps clear up pimples and blackheads (comedones) in acne lesions and reduces inflammation and the spread of acne. Psoriasis is characterised by raised scaly plaques due to excess proliferation and abnormal differentiation of the keratinocytes also by infiltration of immune cells, which produce chemicals called cytokines that are thought to be responsible for this abnormal behaviour as well as causing inflammation. Tazarotene in Tazorac Gel reverses the abnormal changes in keratinocyte behaviour and the inflammatory response. This reduces the scaling and thickening of the psoriatic plaques and relieves symptoms of psoriasis.

What does Tazorac Gel contain?

Tazorac Gel 0.1% contains the active ingredient tazarotene, a topical medication treatment for acne and psoriasis. It also contains ascorbic acid, butylated hydroxyanisole, butylated hydroxytoluene, carbomer homopolymer type B, edetate disodium, hexylene glycol, poloxamer 407, polyethylene glycol 400, polysorbate 40, purified water, and tromethamine.

Treating acne with Tazorac Gel

Tazorac Gel 0.1% contains tazarotene, a pro-retinoid that binds to receptors for vitamin A and affects the way skin cells grow and behave. Acne forms when over stimulation of the sebaceous glands (oil producing glands in hair follicles), which often happens in response a surge of androgen hormones at puberty, causes pores to become clogged with dead skin, and leads to the formation of new pimples, whitehead and blackheads (comedones), which can become infected and inflamed. Tazarotene in Tazorac Gel 0.1% prevents formation of new pimples and blackheads by blocking the hardening processes of the outer skin layer (keratinisation and cornification) and increasing the shedding of old hardened skin cells, while at the same time preventing epidermal hyperproliferation, which is excessive growth of the upper layer of skin cells or keratinocytes. It is also thought to have anti-inflammatory properties. The combined effect of these actions is to unblock pores and prevent them becoming clogged and inflamed, which reduces the outbreak of new pimples as well as clearing up existing blemishes, which helps clear up pimples and blackheads and reduces the spread of acne.

Tazorac Gel for Psoriasis

Tazorac Gel 0.1% contains tazarotene, a pro-retinoid that binds to receptors for vitamin A and affects the way skin cells grow and behave. Psoriasis is characterised by raised scaly plaques due to excess proliferation and abnormal differentiation of the keratinocytes also by infiltration of immune cells, which produce chemicals called cytokines that are thought to be responsible for this abnormal behaviour as well as causing inflammation. Tazarotene in Tazorac Gel 0.1% blocks the hardening processes of the outer skin layer (keratinisation and cornification) and increases the shedding of old hardened skin cells, while at the same time preventing epidermal hyperproliferation, which is excessive growth of the upper layer of skin cells or keratinocytes. It is also thought to have anti-inflammatory properties. Tazarotene in Tazorac Gel reverses the abnormal changes in keratinocyte behaviour and the inflammatory response, which reduces the scaling and thickening of the psoriatic plaques and relieves symptoms of psoriasis, including extreme itching, pain and discomfort.

What are the side effects of Tazorac Gel?

The most commonly reported side effects when taking Tazorac Gel include itching, dryness, redness, burning, stinging, skin discolouration, rash blistering and peeling at the site of application.

When should Tazorac Gel not be used?

You should not use Tazorac Gel if you:
  • are allergic to tazarotene or any ingredients in Tazorac Gel
  • are pregnant or are breastfeeding, as tazarotene may cause birth defects
  • have sunburn or acute eczema, as tazarotene can cause severe irritation on damaged and eczematous skin
  • are using dermatologic medications and cosmetics that have a strong drying effect
  • are exposed to sunlight for prolonged periods, as tazarotene increases sensitivity of the skin to sunlight. If unavoidable use a sunscreen and protective clothing over treated areas to protect the skin.
  • are taking other drugs that increase sensitivity to sunlight, including, thiazide diuretics, tetracycline fluoroquinolone and sulfonamide antibiotics, phenothiazines antipsychotics

Should you avoid exposure to sun?

You should avoid or at least minimize unprotected exposure to sunlight, including sunlamps, during the use of Tazorac Gel 0.1%, as tazarotene can increase your sensitivity to sunlight and may cause burning. Also if you have sunburn, you should wait until your skin has healed before using Tazorac Gel. If you cannot avoid exposure to sun because of your occupation, for example, make sure you use a sunscreen and protective clothing over treated areas to protect the skin.

How should Tazorac Gel be used?

You should apply your Tazorac Gel 0.1% to the affected area of the skin once daily preferably in the evening before going to bed. Clean the skin with a mild soap or soap-free cleanser, rinse with water and ensure the skin is fully dry then apply a small amount with clean fingers and rub gently into the skin. Do not use large amounts or apply Tazorac Gel 0.1% more often than directed, as your skin will not clear up faster, instead you may increase the chance for side effects like skin irritation. Avoid contact with the eyes, eyelids, inside of the nose and mouth, which are easily irritated areas, or other areas where treatment is not intended. Do not apply to severely inflamed skin or to open lesions. With acne an improvement should be seen within two to three weeks, but it may take more than six weeks before you see definite beneficial effects. With psoriasis plaques and scales will usually begin to improve in about one to two weeks, although the redness may take longer to improve. You should continue to use Tazorac Gel 0.1% for the full course of treatment as directed by your doctor, which may be for several weeks.

How long should you use Tazorac Gel?

You should continue to use Tazorac Gel 0.1% for the full course of treatment as directed by your doctor, which may be for several weeks.

Missed dose of Tazorac Gel

If you miss a dose of Tazorac Gel apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose.

How should Tazorac Gel be stored?

You should store your Tazorac Gel below 25°C in a cool dry place.


To satisfy the requirements of Regulation 7 of the UK Medicines (Advertising) Regulations 1994, this site is not intended for those people who reside in the United Kingdom.
What is this ?
Please select your country to display all the products we are able to supply to you.
What is this ?
Select the currency that you would like to display the prices in. This will be the currency that appears on your credit card statement.