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Genox 10mg (Tamoxifen) 100's

Genox general information

What is Genox used for?

Genox tablets 10mg (also known as Nolvadex and Tamofen) are used to treat breast cancer and endometrial cancer. Genox tablets 10mg reduce the growth of early stage tumours and can slow down the growth of advanced metastatic tumours that have already spread to other parts of the body, reducing mortality rates, particularly if taken continuously for 5 years. In women who have received other treatment for breast cancer, such as chemotherapy, Genox tablets 10mg are used as adjuvant therapy, to increase the chances of a cure and reduce the risk of breast cancer returning to the same breast or new tumours developing in the other breast. Genox tablets 10mg also reduce the risk of developing breast cancer in women who are at risk.

How does Genox work?

Genox tablets 10mg (also known as Nolvadex and Tamofen) contain tamoxifen, which is a non-steroidal anti-oestrogen, also known as a selective oestrogen receptor modulator (SERM), that binds to the oestrogen receptor on breast cancer cells blocks the action of oestrogen in these cells, which is to promote the development of beast cancer, and stimulate breast cancer cell growth. Most, but not all, breast cancers are sensitive to oestrogen and are known as oestrogen receptor-positive because they are oestrogen-dependent tumours and the cells contain oestrogen receptors. Genox tablets 10mg are more effective on oestrogen receptor-positive breast cancers and can block or slow down the growth of these tumours at early and late stages, as well as preventing the spread of advanced tumours to other parts of the body. Although tamoxifen in Genox tablets 10mg acts as an anti-oestrogen (antagonist) in breast cancers, it can act as an oestrogen agonist (mimic) in other cells, such as bone cells, which can provide some benefits, for example helping to maintain bone density and reducing the risk of osteoporosis (brittle bones), also reducing levels of blood total cholesterol, particularly in menopausal women.

What does Genox contain?

Genox tablets 10mg contain the active ingredient tamoxifen citrate, a non-steroidal anti-oestrogen that is used to treat breast cancer. They also also contain mannitol, maize starch, purified water, croscarmellose sodium and magnesium stearate.

Treating breast cancer with Genox

Genox tablets 10mg (also known as Nolvadex and Tamofen) contain tamoxifen that acts as anti-oestrogen and binds to the oestrogen receptor on breast cancer cells, blocking the action of oestrogen in oestrogen-dependent breast tumours. Genox tablets 10mg reduce the growth of early stage tumours and can slow down the growth of advanced metastatic tumours that have already spread to other parts of the body, reducing mortality rates, particularly if taken continuously for 5 years. In women who have received other treatment for breast cancer, such as chemotherapy, Genox tablets 10mg are used as adjuvant therapy, to increase the chances of a cure and reduce the risk of breast cancer returning to the same breast or new tumours developing in the other breast. Genox tablets 10mg can also reduce the risk of developing breast cancer in women who are at risk of developing breast cancer.

What are the side effects of Genox?

Most of the commonly reported side effects when using Genox tablets 10mg are generally mild and some are similar to menopausal symptoms; they include: hot flushes, vaginal bleeding, discharge and itching, fluid retention; also nausea, diarrhoea, indigestion, lightheadedness, skin rash, suppression of menstruation in pre-menopausal women.

What are the health risks of Genox?

There is an increased risk of blood clots when taking Genox tablets 10mg, particularly if you have received other treatments such as chemotherapy; also an increased risk of uterine cancer, just as there is when taking oestrogen for hormone replacement therapy.

When should Genox not be used?

You should not use Genox if you:
  • are allergic to tamoxifen or any ingredient in Genox tablets 10mg
  • are pregnant or planning to become pregnant
  • have had or have a history of abnormal blood clots, such as deep venous thrombosis, thromboembolic disorders, cerebral vascular accident associated with oestrogen
  • are taking other medications that may interact with Genox, including: anticoagulants like warfarin, other breast cancer medication like cytotoxic drugs (chemotherapy)

How should Genox be taken?

You should take Genox tablets 10mg with a glass of water and with food, once or twice a day, for as long as recommended by your doctor. Based on clinical triasl, Genox tablets 10mg get the best results when taken continuously for 5 years.

How long should you take Genox?

Based on clinical trials, Genox tablets 10mg get the best results when taken continuously for 5 years.

Missed dose of Genox

If you miss a dose of Genox tablets 10mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Genox be stored?

You should store your Genox tablets 10mg in their blister pack in a cool dry place, at room temperature below 25°C; keep away from direct sunlight.


Neurontin 400mg (Gabapentin)

Neurontin general information

What is Neurontin used for?

Neurontin capsules 400mg are used to treat epilepsy to control seizures in several forms of epilepsy, ranging from partial to generalized tonic-clonic seizures, in adults who have not responded to other antiepileptic drugs; also to control partial seizures in children. Neurontin capsules are also used to control neuropathic (nerve) pain in adults, including, painful diabetic neuropathy and post-herpetic neuralgia, caused by shingles (herpes zoster), to reduce pain sensations primarily in the arms and legs, such as burning, stabbing, or shooting pain, with tingling numbness or pins and needles.

How does Neurontin work?

Neurontin capsules 400mg contain gabapentin, an anticonvulsant that is thought to work by controlling certain neurotransmitters (chemicals that allow nerve cells to communicate) that send nerve signals from the brain causing seizures or nerve pain. Gabapentin in Neurontin capsules is an analogue of, and has a similar chemical structure to the neurotransmitter GABA (gamma-aminobutyric acid). GABA is the major inhibitory neurotransmitter that reduces transmission of nerve signals from the brain to other parts of the central nervous system. Gabapentin in Neurontin capsules does not work through the same receptors as GABA and therefore has a different mechanism of action to other GABA analogues like barbiturates and benzodiazepines, however, it does bind to a receptor in the brain, that has yet to be determined and it is thought to control neurotransmission via voltage-gated calcium channels, which are ion channels in the cell membranes of nerve cells involved in the propagation of electrical signals. Neurontin capsules 400mg reduce the amount of nerve excitation that causes epileptic seizures and nerve pain, which helps control symptoms associated with epilepsy and neuropathic pain.

What does Neurontin contain?

Neurontin capsules contain the active ingredient gabapentin (400mg), an anticonvulsant that is used to control epileptic seizures and nerve pain. They also contain: lactose, talc-purified, starch maize, gelatine, titanium dioxide, Opacode Blue S-1-4118, iron oxide - yellow

Treating epilepsy with Neurontin

Neurontin capsules 400mg contain gabapentin, an anticonvulsant that is used to control seizures in several forms of epilepsy, ranging from partial to generalized tonic-clonic seizures, in adults who have not responded to other antiepileptic drugs; also to control partial seizures in children. Epilepsy is due to an imbalance of neurotransmitters (chemicals that allow nerve cells to communicate), which cause bursts of electrical activity in the brain sending nerve signals from the brain to the central nervous system that triggers seizures. Neurontin 400mg are not effective in forms of epilepsy that do not have seizures (absence and myoclonic). Although the exact mechanism of action of Neurontin 400mg is not known, it is thought to work by suppressing transmission of certain excitatory nerve signals from the brain to the central nervous system which reduces epileptic seizures.

Neurontin for nerve pain

Neurontin capsules 400mg contain gabapentin, an anticonvulsant that is also effective at reducing nerve pain and is used to control several types of neuropathic (nerve) pain in adults, including, painful diabetic neuropathy and post-herpetic neuralgia, caused by shingles (herpes zoster). Although the exact mechanism of action of Neurontin 400mg is not known, it is thought to work by binding to specific receptors in the brain, which suppresses transmission of certain excitatory nerve signals from the brain to the central nervous system, and this reduces pain sensations primarily in the arms and legs, such as burning stabbing shooting or shooting pain, with tingling numbness or pins and needles.

What are the side effects of Neurontin?

The most commonly reported side effects when taking Neurontin capsules 400mg include: dizziness or light-headedness, fatigue, drowsiness, fever, lack of coordination (ataxia), gastrointestinal upset (constipation, diarrhoea, nausea, vomiting), dry mouth, red swollen gums, muscle pain, cramps, back pain, forgetfulness, loss of concentration confusion or abnormal thinking, difficulty speaking, weight changes, hypertension, vasodilatation, visual disturbances, peripheral oedema (swelling of the hands or feet), nystagmus (involuntary eye movement), skin rash, itching. Other side effects more common in children include: infection, emotional lability.

When should Neurontin not be used?

You should not use Neurontin capsules 400mg if you:
  • are allergic to gabapentin or any ingredients in Neurontin capsules
  • are pregnant or are breastfeeding, without discussion with your doctor
  • have mixed seizure disorders that include absence seizures
  • have kidney disease
  • develop pancreatitis
  • are taking medicines that interact with Neurontin, including: cimetidine for peptic ulcers, antacids for reflux, the opiate analgesic morphine

How should Neurontin be taken?

You should take your Neurontin capsules 400mg whole with a glass of water with or without food, 3 times daily and do not allow more than 12 hours between doses. The dose you take depends on what you are being treated for and your doctor’s recommendations. Your doctor may increase your dose gradually depending on how well your condition is controlled. You should not suddenly stop taking your Neurontin 400mg as this may cause withdrawal side effects, instead your doctor will reduce your dose gradually over one week, when you are ready to discontinue treatment. You should continue to take your Neurontin capsules 300mg for as long as recommended by your doctor even if you are feeling better, as Neurontin 400mg helps control your condition but does not cure it.

How long should you take Neurontin?

You should continue to take your Neurontin capsules 400mg for as long as recommended by your doctor even if you are feeling better, as Neurontin 400mg helps control your condition but does not cure it.

Missed dose of Neurontin

If you miss a dose of Neurontin capsules 400mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Neurontin be stored?

You should keep your Neurontin capsules 400mg in their blister packs until use and store below 30°C in a cool dry place.



Cardinol 160 LA (Propranolol)

Cardinol general information

What is Cardinol used for?

Cardinol 160mg capsules are used to treat a variety of conditions including, control of hypertension (high blood pressure); management of angina (chest pain) and long-term prevention of myocardial infarction (heart attack). Cardinol capsules 160 LA work through a common mechanism in several different body systems to manage the condition and relieve symptoms by reducing heart rate (pulse), workload (force needed to pump) and oxygen demand, increasing blood flow and lowering blood pressure.

How does Cardinol work?

Cardinol capsules 160mg contain propanolol, which is a beta-blocker or selective beta-receptor antagonist and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works via beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are blocked by propanolol in Cardinol capsules 160mg, to slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. Since beta-receptors are found in many tissues, particularly the heart, kidneys, vascular smooth muscle in blood vessel walls, lung, skeletal muscle and liver, all short-term and long-term symptom relief due to taking Cardinol capsules 160 LA, is based on blocking beta-receptors in the target tissue. Cardinol capsules 160mg are formulated for long acting slow release of propanolol over a 24 hour period so that you need only take one capsule a day.

What Cardinol doses are available?

Cardinol is available to order and buy online from Inhouse Pharmacy in the following doses:
  • Cardinol 10mg tablets
  • Cardinol 40mg tablets
  • Cardinol 160mg capsules (long-acting slow release)

What does Cardinol contain?

Cardinol 160mg capsules contain spheroids of the active ingredient propanolol hydrochloride, a beta-blocker and beta-receptor agonist that blocks the action of adrenaline to slow heart rate and relax blood vessels, amongst other actions. These spheroids have a sustained release coating to provide long action. Propanolol Cardinol 160mg capsules also contain sucrose, maize starch, shellac, talc and the gelatin capsule.

What is the difference between Cardinol long acting capsules and Cardinol tablets?

Cardinol tablets are formulated for rapid release and absorption and contain lower concentrations of active ingredient than capsules. Cardinol capsules contain slow release spheroids which release the active ingredient over a longer time period for slower but sustained drug absorption, which means that you need only take one capsule a day to get the same dose of drug as several tablets taken each day.

Treating high blood pressure (hypertension) with Cardinol

Cardinol capsules 160mg contain propanolol, a beta-blocker that blocks the action of adrenaline in stimulating beta-receptors in blood vessel walls, causing blood vessels to constrict (narrow) which reduces blood flow and raises blood pressure. Cardinol capsules 160 LA are used to treat high blood pressure (hypertension) by widening blood vessels, reducing heart rate (number of heart beats) and reducing the force of the heart contraction. These actions lower blood pressure and help the heart to cope better,
Reducing heart rate with Cardinol
Cardinol 160mg capsules contain propanolol, a beta-blocker that blocks the action of adrenaline in stimulating beta-receptors in the heart muscle. Adrenaline increases heart rate and the strength of muscular contraction in response to excitement/physical exertion. Cardinol capsules 160 LA are used for management of angina (chest pain) and long-term prevention of myocardial infarction (heart attack) by widening blood vessels, reducing heart rate and the force of contraction of the heart. When the heart does not have to work as hard, it requires less oxygen and relieves symptoms of angina including chest pain and breathlessness on exertion.

What are the side effects of Cardinol?

The mot common side effects reported while taking Cardinol capsules 160mg include: tiredness, dizziness, sleep disturbances or nightmares, hair loss, mood changes or confusion, dry eyes, nausea, vomiting, diarrhoea, stomach pain.

When should Cardinol not be used?

You should not use Cardinol capsules 160mg if you:
  • are allergic to propranolol hydrochloride or any other ingredients in Cardinol 160 LA
  • have a history of bronchial asthma or bronchospasm
  • are diabetic and taking hypoglycaemic therapy as propranolol may prolong the hypoglycaemic response to insulin
  • have, poor peripheral blood circulation, uncontrolled heart failure, low blood pressure (hypotension), metabolic acidosis (too much acid in your blood) or a certain type of angina called Prinzmetal's angina
  • have a phaeochromocytoma (a rare tumour of the adrenal gland) which is not already being treated with other medicines
  • have certain other heart problems
  • are taking medication that may interact with Cardinol 160mg capsules, including: other medicines for high blood pressure; angina or an irregular heart beat such as calcium channel blockers (disopyramide) digoxin, clonidine, hydralazine, diltiazem, verapamil, and nifedipine; adrenaline for emergencies like anaphylaxis; ergotamine and derivatives for migraine; antiinflammatories like ibuprofen or indomethacin; cimetidine for reflux and ulcers; chlorpromazine for psychiatric disorders

How should Cardinol be taken?

You should take your Cardinol capsules 160mg with a glass of water, swallowed whole with or without food, usually once daily either morning or evening, but at the same time each day. You should take Cardinol capsules 160 LA according to your doctor’s recommendations and the number of capsules you take each day, how often you take them and for how long depends on the condition you are being treated for. The dose you are taking may be increased by your doctor. You must take your capsules every day, as instructed and if you are advised to stop taking them, withdrawal should be gradual and treatment should not be discontinued abruptly.

How long should you take Cardinol?

You should take your Cardinol capsules 160mg for as long as your doctor recommendations, which may be for a few days or weeks, depending on the condition you are being treated for.

Missed dose of Cardinol

If you miss a dose of Cardinol capsules 160mg, take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How Cardinol name be stored?

You should store your Cardinol capsules 160mg below 25°C, protected from light and moisture.


Symmetrel 100mg (Amantadine)

Symmetrel general information

What is Symmetrel used for?

Symmetrel capsules 100mg are used to treat Parkinson's disease, a neurological disorder that is either idiopathic, which means that its cause is unknown or secondary to a known cause such as stroke, head trauma or as a side effect of medication, particularly neuroleptic antipsychotics. Symmetrel 100 may be used alone as monotherapy, or in combination with other medications, like anticholinergic drugs or levodopa and helps relieve symptoms of Parkinsonism and Parkinson's disease, including tremor, bradykinesia (slowness of movement) and loss of balance. Symmetrel capsules 100mg are also used as prophylaxis to prevent signs and symptoms of infection caused by influenza A virus, particularly for those at high risk of infection, if vaccination is unavailable or contraindicated, and for those at risk of serious illness if they were to become infected, such as being immunocompromised or having lung problems; also to treat flu-like symptoms if administered within 48 hours.

How does Symmetrel work?

Symmetrel capsules 100mg contain amantadine, which is an antiparkinsonian drug with virostatic properties. The abnormal movements associated with Parkinsonism and Parkinson's disease are caused by low levels of dopamine, a neurotransmitter (chemical that allows communication between nerve cells) produced by certain neurons (nerve cells) in the brain and plays an important role in controlling muscle function and movement; it is important to have the correct levels of dopamine. The loss of dopamine seen in Parkinson's disease is due to slow and progressive destruction of the neurons that produce the dopamine in a certain area of the brain called the substantia nigra. Amantadine in Symmetrel 100 is thought to increase the amount of dopamine in the brain by enhancing the release of dopamine from central neurons and by delaying its re-uptake from the synapse, the gap between nerve cells across which chemical messages are sent from one nerve cell to another. The increase in dopamine levels helps the brain control muscle function and restore normal movement. Amantadine in Symmetrel 100 is also thought to exert some anticholinergic activity, which means that it blocks the binding of the neurotransmitter acetylcholine to its receptor in nerve cells and this action helps prevent the involuntary movements associated with Parkinsonism. The mechanism of action by which Symmetrel 100 prevents the growth of influenza A virus is not known but it is thought to be due to interference with a viral protein needed for the virus to infect the host cell and this inhibits the early stage of replication of the influenza A virus and checks the growth of virus.

What does Symmetrel contain?

Symmetrel capsules 100mg contain the active ingredient amantadine hydrochloride, used to treat Parkinson's disease and to treat and prevent symptoms of influenza A virus. They also contain: rape seed oil, lecithin, a wax blend composed of white beeswax and hydrogenated soya and vegetable oils, sodium ethyl hydroxybenzoate, gelatin, glycerol, iron oxide red CI 77491, sorbitol, sodium propyl hydroxybenzoate, titanium dioxide.

Treating Parkinson's disease with Symmetrel

Symmetrel capsules 100mg contain amantadine, which is an antiparkinsonian drug used to treat neurological symptoms that cause the abnormal movements associated Parkinsonism and Parkinson's disease. Parkinson's disease is a neurological disorder that is either idiopathic, which means that its cause is unknown, or secondary to a known cause such as stroke, head trauma or as a side effect of medication, particularly neuroleptic antipsychotics. Parkinsonism is caused by low levels of dopamine, a neurotransmitter (chemical that allows communication between nerve cells) produced by certain neurons (nerve cells) in the brain that plays an important role in controlling muscle function and movement. This loss of dopamine is due to slow and progressive destruction of the dopamine-producing neurons in the substantia nigra area of the brain. Amantadine in Symmetrel 100 is thought to increase the amount of dopamine in the brain by enhancing the release of dopamine from central neurons and by delaying its re-uptake from the synapse, the gap between nerve cells across which chemical messages are sent from one nerve cell to another. The increase in dopamine levels helps the brain control muscle function and restore normal movement. Amantadine in Symmetrel 100 is also thought to exert some anticholinergic activity, which means that it blocks the binding of the neurotransmitter acetylcholine to its receptor in nerve cells and this action helps prevent the involuntary movements associated with Parkinsonism. Symmetrel 100 may be used alone (monotherapy), or in combination with other medications, like anticholinergic drugs or levodopa and helps relieve symptoms of Parkinsonism and Parkinson's disease, including tremor, bradykinesia (slowness of movement) and loss of balance.

Treating symptoms of influenza A infection with Symmetrel

Symmetrel capsules 100mg contain amantadine, which is an antiparkinsonian drug with influenzal virostatic properties, which means that it specifically blocks the growth of the Influenza A virus. Although the mechanism of action by which Symmetrel 100 prevents the growth of influenza A virus is not known it is thought to be due to interference with a viral protein needed for the virus to infect the host cell and this inhibits the early stage of replication of the influenza A virus. Symmetrel capsules 100mg are used as prophylaxis to prevent signs and symptoms of infection caused by influenza A virus, particularly for those at high risk of infection, if vaccination is unavailable or contraindicated, and for those at risk of serious illness if they were to become infected, such as being immunocompromised or having lung problems; also to treat flu-like symptoms if administered within 48 hours.

What are the side effects of Symmetrel?

The most commonly reported side effects when taking Symmetrel capsules 100mg include: depression, anxiety, elevation of mood, agitation, nervousness, difficulty in concentrating, dizziness, light-headedness, headache, insomnia, lethargy, hallucinations, nightmares, ataxia, slurred speech, blurred vision, oedema of ankles, livedo reticularis (purplish-red blotchy spots on the skin), dry mouth, anorexia, nausea, vomiting, constipation, palpitations, orthostatic hypotension, excessive sweating.

When should Symmetrel not be used?

You should not use Symmetrel capsules 100mg if you:
  • are allergic to amantadine or any ingredients in Symmetrel
  • are pregnant or are breastfeeding
  • have kidney or liver disease
  • have or have had recurrent eczema, stomach ulcers, or cardiovascular disorders
  • suffer from convulsions or psychiatric disorders
  • are taking medicines that interact with Symmetrel, including: other antiparkinsonian drugs, like anticholinergics or levodopa (without discussion with your doctor), other medicines that act on the central nervous system, like sedatives, analgesics and alcohol, combination diuretics, like hydrochlorothiazide + potassium-sparing diuretics

What medications interact with Symmetrel?

Several medications interact with Symmetrel capsules 100mg and should either not be taken while you are taking Symmetrel or only after discussion and instruction from your doctor:
  • Drugs that increase side effects with Symmetrel: other antiparkinsonian drugs, like anticholinergics or levodopa,
  • Drugs that cause dangerous reactions with Symmetrel: other medicines that act on the central nervous system, like sedatives, analgesics and alcohol
  • Drugs that affect Symmetrel: combination diuretics, like hydrochlorothiazide + potassium-sparing diuretics

How should Symmetrel be taken for Parkinson's disease?

You should take your Symmetrel capsules 100mg with a glass of water once daily and preferably with food to prevent stomach problems. Your doctor may increase the dose to one capsule twice daily, depending on your condition. You should see some benefit within a few days and should continue to take your Symmetrel 100 for as long as recommended by your doctor, which may be for a long time depending on your condition. For some people the effectiveness of Symmetrel 100 wears off after a few months of continuous treatment, if this is the case your doctor may recommend that you gradually reduce the dose and stop it for a few weeks, then start again.

How should Symmetrel be taken for influenza A?

You should take your Symmetrel capsules 100mg with a glass of water twice daily and preferably with food to prevent stomach problems, or once daily for children or adults over 65. For prophylaxis you should start taking Symmetrel as soon as possible after you have been exposed to the flu and keep taking it through outbreak for at least 10 days or until the outbreak of influenza A is over. For treatment you should start taking Symmetrel 100 within 48 hours of the first symptoms onset and then for 4-5 days.

How long should you take Symmetrel?

For Parkinson's disease you should continue to take your Symmetrel capsules 100mg for as long as recommended by your doctor, which may be for a long time depending on your condition. For prophylaxis against influenza A, you should start taking Symmetrel capsules 100mg as soon as possible after you have been exposed to the flu and keep taking it through outbreak for at least 10 days or until the outbreak of influenza is over. For treatment you should start taking Symmetrel 100 within 48 hours of the first symptoms onset and then for 4-5 days.

Missed dose of Symmetrel

If you miss a dose of Symmetrel capsules 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Symmetrel be stored?

You should store your Symmetrel below 25°C in a cool dry place. Protect from moisture and heat.



Rimadyl 75mg (Carprofen) 14's

Rimadyl general information

What is Rimadyl used for?

Rimadyl chewable tablets 75mg are a medication used for dogs to treat and manage the pain and inflammation that can be caused by osteoarthritis. Many dogs suffer from osteoarthritis, particularly as they age. Osteoarthritis is caused by wear and tear of the joints and can cause pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness. Rimadyl chewable tablets 75mg can help relieve symptoms of osteoarthritis and improve your dog’s mobility. Rimadyl chewables are also used to reduce pain following orthopaedic and soft tissue surgery in dogs. Rimadyl chewable tablets 75mg are intended for use for dogs only and should not be given to cats or other pets.

How does Rimadyl work?

Rimadyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class that has anti-inflammatory, analgesic (pain relief) and antipyretic (reduces fever) properties. NSAIDs inhibit the cyclooxygenase (COX) enzyme responsible for the production of chemicals called prostaglandins, which are mediators of a variety of cellular processes as well as inflammation. There are two COX enzymes, COX-1 which is needed for normal cell functions and COX-2 which is involved in the inflammatory process. Carprofen in Rimadyl chewables acts specifically on the inhibition of COX-2 resulting in anti-inflammatory activity which relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.

What does Rimadyl contain?

Rimadyl chewable tablets 75mg contain the active ingredient carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat osteoarthritis in dogs.

What doses of Rimadyl are available?

Rimadyl chewable tablets are available from Inhouse Pharmacy in 3 doses:
  • 25mg chewable tablets in packets of 60 tablets
  • 75mg chewable tablets in packets of 14 tablets
  • 100mg chewable tablets in packets of 60 tablets

Treating osteoarthritis in dogs with Rimadyl

Rimadyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat dogs to help manage the pain and inflammation caused by osteoarthritis. Many dogs suffer from osteoarthritis, particularly as they age. Osteoarthritis is caused by wear and tear of the joints, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness. Carprofen in Rimadyl chewables specifically inhibits the COX-2 enzyme responsible for the production of chemicals called prostaglandins, which are mediators of inflammation. The anti-inflammatory activity of Rimadyl chewable tablets 75mg relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.

What are the side effects of Rimadyl?

The most commonly reported side effects in dogs when given Rimadyl chewable tablets 75mg include: gastrointestinal problems; vomiting, diarrhoea and loss of appetite, lethargy and behavioural changes. If you observe signs of intolerance to chewable Rimadyl tablets 75mg in your dog you should stop giving them Rimadyl chewables and seek help from your vet.

When should Rimadyl not be used?

You should not give Rimadyl chewable tablets 75mg to your dog if your dog:
  • has a sensitivity reaction to carprofen or any other NSAID or any other ingredients in Rimadyl chewables
  • is younger than 6 months
  • is pregnant or lactating
  • has a heart condition, liver or kidney disease or bleeding disorders
  • has been given other NSAID medication, corticosteroids, some heart drugs (ACE inhibitors) and some drugs for seizure control

How should Rimadyl be given to your dog?

You should give your dog Rimadyl chewable tablets 75mg by mouth, with or without food and according to your vet’s instructions. The recommended dose is 2mg/lb or 4.4mg/kg of body weight daily, which can be given as a single dose once daily or divided and into two doses given as 1mg/lb or 2.2mg/kg twice daily. Rimadyl chewables will help relieve symptoms of osteoarthritis in your dog and you should see signs of improvement within a few days. However Rimadyl chewable tablets 75mg will not cure your dog’s osteoarthritis, so you should continue to give them to your dog for as long as recommended by your vet.

How long should you give Rimadyl to your dog?

Rimadyl chewable tablets 75mg will help relieve symptoms of osteoarthritis in your dog and you should see signs of improvement within a few days, Rimadyl chewables will not cure your dog’s osteoarthritis, so you should continue to give them to your dog for as long as recommended by your vet.

Missed dose of Rimadyl

If you forget to give a dose of Rimadyl chewable tablets 75mg to your dog, administer it as soon as you remember, unless it is time to give the next dose, then skip the missed dose. Do not give your dog a double dose.

How should Rimadyl be stored?

You should store your dog’s Rimadyl chewable tablets 75mg below 25°C in a cool dry place and protect from light.


All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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