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Carodyl 100 (Carprofen 100mg)

Carodyl general information

What is Carodyl used for?

Carodyl chewable tablets 100mg are a medication used for dogs to treat and manage the pain and inflammation that can be caused by osteoarthritis.  Many dogs suffer from osteoarthritis, particularly as they age.  Osteoarthritis is caused by wear and tear of the joints and can cause pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness.  Carodyl 100 can help relieve symptoms of osteoarthritis and improve your dog’s mobility.  Carodyl 100 is also used to reduce pain following orthopaedic and soft tissue surgery in dogs.  Carodyl 100 are intended for use for dogs only and should not be given to cats or other pets.

How does Carodyl work?

Carodyl chewable tablets 100mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class that has anti-inflammatory, analgesic (pain relief) and antipyretic (reduces fever) properties.  NSAIDs inhibit the cyclooxygenase (COX) enzyme responsible for the production of chemicals called prostaglandins, which are mediators of a variety of cellular processes as well as inflammation.  There are two COX enzymes, COX1 which is needed for normal cell functions and COX-2 which is involved in the inflammatory process.  Carprofen in Carodyl 100 acts specifically on the inhibition of COX-2 resulting in anti-inflammatory activity which relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.  Carodyl 100 are available as meaty flavoured chewable tablets that are more palatable and easier for dogs to swallow.

What does Carodyl contain?

Carodyl chewable tablets 100mg contains the active ingredient carprofen a non-steroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation due to osteoarthritis and surgery in dogs. 

Treating osteoarthritis with Carodyl

Carodyl 100 contains carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat dogs to help manage the pain and inflammation caused by osteoarthritis.  Many dogs suffer from osteoarthritis, particularly as they age.  Osteoarthritis is caused by wear and tear of the joints causing pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness.  Carprofen in Carodyl 100 specifically inhibits the COX-2 enzyme responsible for the production of chemicals called prostaglandins, which are mediators of inflammation.  The anti-inflammatory activity of carprofen in Carodyl 100 relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.  

What are the side effects of Carodyl?

The most commonly reported side effects when taking Carodyl 100 include; vomiting, diarrhoea, loss of appetite, lethargy and behavioural changes.

When should Carodyl not be used?

You should not use Carodyl 100 if your dog:

  • has a sensitivity reaction to carprofen or any other NSAID or any ingredients in Carodyl
  • is younger than 6 months
  • is pregnant or lactating
  • has a heart condition, liver or kidney disease or bleeding disorders 
  • has been given other NSAID medication, corticosteroids, some heart drugs (ACE inhibitors), some drugs for seizure control

How should Carodyl be given?

You should give your dog Carodyl 100 chewable tablets by mouth and with food.  The recommended dose is 2-4mg per kg body weight (2.2lb) per day given in two equally divided doses.  The same dose may be reduced to once daily after 7 days, depending on your dog’s response and your veterinarian’s recommendation.  You should see signs of improvement within a few days.  You should continue to give Carodyl 100 to your dog for as long as recommended by your veterinarian, which may be long term, as Carodyl 100 will help relieve symptoms of osteoarthritis in your dog but will not cure your dog’s condition.

Dosage:

10-14kg (22-30lb)                      50mg in half tablet

18-27kg (39.6-59.5)                    100mg in one tablet

27-41kg (59.6-90lb)                    150mg in one and a half tablets

41-55kg (90-121lb)                     200mg in two tablets

How long should you give Carodyl?

You should continue to give Carodyl 100 to your dog for as long as recommended by your veterinarian, which may be long term, as. Carodyl 100 will help relieve symptoms of osteoarthritis in your dog but will not cure your dog’s condition.

Missed dose of Carodyl

If you miss a dose of Carodyl 100 give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Carodyl be stored?

You should store your Carodyl 100 below 25°C in a cool dry place and protect from light. 

Mirena (Levonorgestrel) 20mcg
Nifuran (Nitrofurantoin 50mg)

Nifuran general information

What is Nifuran used for?

Nifuran tablets 50mg are used to treat acute urinary tract infection and prevent recurrent urinary tract infections that are caused by susceptible bacteria.  The most common urinary infection in women is bladder infection or cystitis, and in men infection of the prostate or prostatitis.  Nifuran tablets 50mg are also used to treat pyelitis, which is when the infection has travelled up the urinary tract and reached the kidney, causing pain and inflammation.  Nifuran tablets 50mg are a specific treatment for urinary tract infections but are not used for other types of bacterial infection. .

How does Nifuran work?

Nifuran tablets 50mg contain nitrofurantoin, a broad-spectrum antibiotic that is used specifically to treat urinary tract infection caused by a variety of susceptible bacteria.  Nitrofurantoin in Nifuran tablets 50mg exerts its antibacterial effect by damaging the bacterial DNA which inhibits bacterial replication and prevents the spread of infection.  Riboflavins in the bacterial cell convert nitrofurantoin to a form that is very reactive with bacterial proteins and other macromolecules like DNA, which prevent DNA synthesis as well as other metabolic processes, like production of the bacterial cell wall.  This action of nitrofurantoin in Nifuran tablets 50mg kills the bacteria and prevents spread of infection.  Nifuran tablets 50mg are effective against most of the bacteria that cause urinary tract infections including, Escherichia coli, Enterococcus Faecalis and several species of Klebsiella, Enterobacter, Staphylococcus and Citrobacter.

What does Nifuran contain?

Nifuran tablets 50mg contain the active ingredient nitrofurantoin, an antibiotic that is used specifically to treat urinary tract infection.  They also contain acacia, alginic acid, lactose monohydrate, magnesium stearate, maize starch, sodium laurilsulfate, sucrose.

Treating urinary tract infection with Nifuran

Nifuran tablets 50mg contain nitrofurantoin, a broad-spectrum antibiotic that is used to treat acute urinary tract infection and prevent recurrent urinary tract infections that are caused by susceptible bacteria.  The most common urinary infection in women is bladder infection or cystitis, and in men infection of the prostate or prostatitis.  Nitrofurantoin in Nifuran tablets 50mg is converted by bacterial riboflavins to a form that is very reactive with bacterial proteins and other macromolecules like DNA, which prevent DNA synthesis as well as other metabolic processes like production of the bacterial cell wall.  This antibacterial action of nitrofurantoin in Nifuran tablets 50mg inhibits bacterial replication and prevents the spread of infection. 

What are the side effects of Nifuran?

The most commonly reported side effects when taking Nifuran tablets 50mg include gastrointestinal upset, mainly nausea and flatulence, headache, urine discolouration.  Less common side effects include, peripheral neuropathy, dizziness; drowsiness.

When should Nifuran not be used?

You should not use Nifuran tablets 50mg if you:

  • are allergic to nitrofurantoin or any ingredients in Nifuran
  • are pregnant or are breastfeeding
  • have kidney disease or urine problems, such as producing less urine than normal (oliguria) or having trouble producing any urine (anuria)
  • are taking medicines that interact with Nifuran including antacids containing magnesium trisilicate, probenecid and sulphinpyrazone for gout, quinolone antibiotics

What medications interact with Nifuran?

Several medications interact with Nifuran tablets 50mg and should either not be taken while you are taking Nifuran or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction or increase side effects with Nifuran: probenecid and sulphinpyrazone for gout
  • Drugs that affect Nifuran: antacids containing magnesium trisilicate, probenecid and sulphinpyrazone for gout, quinolone

How should Nifuran be taken?

You should take your Nifuran tablets 50mg swallowed whole with a glass of water and with food or with a glass of milk, 4 times daily for 7 days, if you have an acute urinary tract infection.  For prophylaxis (prevention) of urinary tract infection, you should take one tablet at bedtime for up to 6 months.  You should continue to take your Nifuran tablets 50mg according to your doctor’s recommendations or until you have completed your course.  If you do not complete your course of Nifuran tablets 50mg your infection may not fully clear up or may return. 

How long should you take Nifuran?

You should take your Nifuran tablets 50mg for 7 days for an acute urinary tract infection or for up to 6 months for prophylaxis (prevention) of urinary tract infection.  You should complete your course of Nifuran tablets 50mg or your infection may not fully clear up or may return. 

Missed dose of Nifuran

If you miss a dose of Nifuran tablets 50mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Nifuran be stored?

You should store your Nifuran tablets 50mg below 25°C in a cool dry place. 

Carodyl 75mg (Carprofen 75mg)

Carodyl general information

What is Carodyl used for?

Carodyl chewable tablets 75mg are a medication used for dogs to treat and manage the pain and inflammation that can be caused by osteoarthritis.  Many dogs suffer from osteoarthritis, particularly as they age.  Osteoarthritis is caused by wear and tear of the joints and can cause pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness.  Carodyl 75 can help relieve symptoms of osteoarthritis and improve your dog’s mobility.  Carodyl 75 is also used to reduce pain following orthopaedic and soft tissue surgery in dogs.  Carodyl 75 is intended for use for dogs only and should not be given to cats or other pets.

How does Carodyl work?

Carodyl chewable tablets 75mg contain carprofen a non-steroidal anti-inflammatory drug (NSAID) belonging to the propionic acid class that has anti-inflammatory, analgesic (pain relief) and antipyretic (reduces fever) properties.  NSAIDs inhibit the cyclooxygenase (COX) enzyme responsible for the production of chemicals called prostaglandins, which are mediators of a variety of cellular processes as well as inflammation.  There are two COX enzymes, COX1 which is needed for normal cell functions and COX-2 which is involved in the inflammatory process.  Carprofen in Carodyl 75 acts specifically on the inhibition of COX-2 resulting in anti-inflammatory activity which relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.  Carodyl tablets 75mg are available as meaty flavoured chewable tablets that are more palatable and easier for dogs to swallow.  

What does Carodyl contain?

Carodyl chewable tablets 75mg contains the active ingredient carprofen a non-steroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation due to osteoarthritis and surgery in dogs. 

Treating osteoarthritis with Carodyl

Carodyl 75 contains carprofen a non-steroidal anti-inflammatory drug (NSAID) used to treat dogs to help manage the pain and inflammation caused by osteoarthritis.  Many dogs suffer from osteoarthritis, particularly as they age.  Osteoarthritis is caused by wear and tear of the joints causing pain, swelling and stiffness, particularly in the legs, hips and backbone, which can restrict your dog’s activity and cause lameness.  Carprofen in Carodyl 75 specifically inhibits the COX-2 enzyme responsible for the production of chemicals called prostaglandins, which are mediators of inflammation.  The anti-inflammatory activity of carprofen in Carodyl 75 relieves the pain, swelling and stiffness in the joints caused by osteoarthritis.  

What are the side effects of Carodyl?

The most commonly reported side effects when taking Carodyl 75 include; vomiting, diarrhoea, loss of appetite, lethargy and behavioural changes.

When should Carodyl not be used?

You should not use Carodyl 75 if your dog:

  • has a sensitivity reaction to carprofen or any other NSAID or any ingredients in Carodyl
  • is younger than 6 months
  • is pregnant or lactating
  • has a heart condition, liver or kidney disease or bleeding disorders 
  • has been given other NSAID medication, corticosteroids, some heart drugs (ACE inhibitors), some drugs for seizure control

How should Carodyl be given?

You should give your dog Carodyl 75 chewable tablets by mouth and with food.  The recommended dose is 2-4mg per kg body weight (2.2lb) per day given in two equally divided doses.  The same dose may be reduced to once daily after 7 days, depending on your dog’s response and your veterinarian’s recommendation.  You should see signs of improvement within a few days.  You should continue to give Carodyl 75 to your dog for as long as recommended by your veterinarian, which may be long term, as Carodyl 75 will help relieve symptoms of osteoarthritis in your dog but will not cure your dog’s condition.

Dosage:

7-10kg (15.4–22lb)                     37.5mg in half tablet

14-18kg (30-39.6lb)                    75mg in one tablet

How long should you give Carodyl?

You should continue to give Carodyl 75 to your dog for as long as recommended by your veterinarian, which may be long term, as. Carodyl 75 will help relieve symptoms of osteoarthritis in your dog but will not cure your dog’s condition.

Missed dose of Carodyl

If you miss a dose of Carodyl 75 give it as soon as you remember, unless it is time to give the next dose, then skip the missed dose.  Do not give a double dose.

How should Carodyl be stored?

You should store your Carodyl 75 below 25°C in a cool dry place and protect from light. 

Oruvail SR (Ketoprofen 200mg)

Oruvail general information

What is Oruvail used for?

Oruvail SR capsules 200mg are used to help manage symptoms caused by various chronic inflammatory diseases.  These include rheumatoid arthritis, osteoarthritis (wear and tear) and ankylosing spondylitis, (an autoimmune inflammatory disease that affects the joints in the spine and pelvis and can cause fusion of the spine) to reduce pain, inflammation, tenderness, stiffness and swelling in the affected joints.  Oruvail SR capsules 200mg do not cure the underlying disease but can relieve symptoms of pain and inflammation and improve the functional use of affected joints.  Oruvail SR capsules 200mg are also used for acute articular and periarticular disorders, such as bursitis (inflammation of the fluid filled sac in the joints), capsulitis (inflammation of tendons in joints), synovitis (inflammation of the membrane surrounding joints), tendonitis (inflammation of tendons), fibrositis (inflammation of connective tissues in muscles and joints), cervical spondylitis (wear and tear in the neck spinal disks); also for musculoskeletal disorders, such as sprains, strains, lower back pain (lumbago, sciatica) and for gout (uric acid crystals in the joints) to relieve chronic pain and inflammation.  Oruvail SR capsules 200mg are also used for relief dysmenorrhoea (menstrual pain) and in the treatment of post-operative pain.   

How does Oruvail work?

Oruvail SR capsules 200mg contain ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that has anti-inflammatory, analgesic (pain relieving) and anti-pyretic properties (reduces fever).  Ketoprofen in Oruvail SR capsules 200mg blocks the production of specific chemicals called prostaglandins (PG) that mediate inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) including cyclooxygenase 1 (COX-1) and cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins.  Inhibition of COX-2 helps relieve the symptoms of inflammation, including pain, swelling, and joint stiffness.  Inhibition of COX-1 is responsible for the gastrointestinal side effects that are due to inhibition of protective prostaglandins in the gut and disruption of regulation of acid content.  Oruvail SR capsules 200mg contain multiple microbeads which are are formulated for sustained controlled release.  This provides a constant concentration of ketoprofen over a period of time, for maximum effectiveness and minimum side effects.   

What does Oruvail contain?

Oruvail SR capsules 200mg contains the active ingredient ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation of chronic inflammatory bone and joint diseases, and other conditions.  They also contain erythrosine, ethylcellulose, gelatin, non-pareil beads (PI 1014), shellac, colloidal anhydrous silica, sodium lauryl sulfate, purified talc and titanium dioxide. The 200mg capsules also contain Opacode Blue (PI 12300).

Treating arthritis with Oruvail

Oruvail SR capsules 200mg contain ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain and inflammation in joints affected with arthritis.  Osteoarthritis a degenerative disease (also known as wear and tear), and rheumatoid arthritis (an autoimmune disease where the immune system turns on self) are chronic inflammatory diseases in which the joints become inflamed, swollen and painful.  Ketoprofen in Oruvail SR capsules 200mg blocks the production of specific chemicals called prostaglandins (PG) that mediate inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) that is responsible for the synthesis of inflammatory prostaglandins.  Inhibition of PG production by ketoprofen in Oruvail SR capsules 200mg helps relieve the symptoms of inflammation, including pain, swelling, and joint stiffness, to improve the functional use of affected joints., but does not cure the underlying disease.

Oruvail for pain and inflammation

Oruvail SR capsules 200mg contain ketoprofen a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat several chronic inflammatory joint diseases to relieve pain and inflammation.  These include rheumatoid arthritis, osteoarthritis (wear and tear), ankylosing spondylitis (an autoimmune inflammatory disease that affects the joints in the spine and pelvis and can cause fusion of the spine).  Oruvail SR capsules 200mg are also used for for musculoskeletal disorders, such as sprains, strains, lower back pain (lumbago) to relieve chronic pain and inflammation; also to treat rheumatic conditions of the connective tissue surrounding joints (non-articular), including bursitis, tendonitis, synovitis and fibrositis.  Oruvail SR capsules 200mg are also used for acute pain and inflammation are also associated with dysmenorrhea (menstrual pain) and post-operative pain (following surgery).  Ketoprofen in Oruvail SR capsules 200mg blocks the production of specific chemicals called prostaglandins (PG) that mediate inflammation, particularly PGE2, and works by inhibiting the enzyme cyclooxygenase (COX) including cyclooxygenase 2 (COX-2) that is induced during the inflammation process and is responsible for the synthesis of inflammatory prostaglandins.  Inhibition of COX-2 helps relieve the symptoms of inflammation, including pain, swelling, and joint stiffness.  Oruvail SR capsules 200mg also inhibit cyclooxygenase 1 (COX-1), which is thought to be responsible for the gastrointestinal side effects associated with the non-selective NSAIDs.  

What are the side effects of Oruvail?

The most commonly reported side effects when taking Oruvail SR capsules 200mg are gastrointestinal and include: upset stomach or stomach pain, diarrhoea, indigestion, bloating wind, heartburn, indigestion, constipation.  Other side effects include dizziness, headache, visual disturbance, tinnitus (buzzing or ringing in the ears), skin rash, oedema and fluid retention. 

When should Oruvail not be used?

You should not use Oruvail SR capsules 200mg if you:

  • are allergic to ketoprofen or any other NSAID including aspirin or any ingredients in Oruvail
  • are pregnant or are breastfeeding, without discussion with your
  • have kidney or liver disease
  • have asthma as ketoprofen may cause bronchospasm
  • have uncontrolled hypertension, severe heart failure or cardiovascular disease, without discussion with your doctor
  • have active or a history of gastrointestinal bleeding or perforation due to an ulcer
  • have a tendency to bleed easily
  • are taking medicines that interact with Oruvailaspirin or other NSAIDs, anticoagulants like warfarin, cholestyramine for high cholesterol, probenecid for gout, the anti-cancer drug methotrexate, lithium for mood disorders, diuretics like frusemide, beta blockers and ACE inhibitors for high blood pressure, digitalis for heart failure, sulphonamide antibiotics, sulphonylureas for diabetes, SSRI antidepressants, corticosteroids

What medications interact with Oruvail?

Several medications interact with Oruvail SR capsules 200mg and should either not be taken while you are taking Oruvail or only after discussion and instruction from your doctor:

  • Drugs that cause a serious reaction with Oruvail: aspirin or other NSAIDs, SSRI antidepressants, anticoagulants like warfarin, and ACE inhibitors
  • Drugs that affect Oruvail: cholestyramine for high cholesterol, probenecid for gout
  • Drugs that are affected by Oruvail: anticoagulants like warfarin, the anti-cancer drug methotrexate, lithium for mood disorders, diuretics like frusemide, beta blockers and ACE inhibitors for high blood pressure, sulphonamide antibiotics, sulphonylureas for diabetes

How should Oruvail be taken?

You should take your Oruvail SR capsules 200mg swallowed whole with a glass of water once daily at the same time each day and with food to reduce risk of gastrointestinal side effects.  The dose you take depends on your condition and your doctor’s recommendation.  You should continue to take your Oruvail SR capsules 200mg for as long as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for.

How long should you take Oruvail?

You should continue to take your Oruvail SR capsules 200mg for as long as recommended by your doctor, which may be for a few days, several weeks or longer, depending on what you are being treated for.

Missed dose of Oruvail

If you miss a dose of Oruvail SR capsules 200mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose.  Do not take a double dose.

How should Oruvail be stored?

You should store your Oruvail SR capsules 200mg below 25°C in a cool dry place. 

All medicines have risks and benefits, and individual results may vary. Only purchase medicines from this site in accordance with the advice you have obtained from an appropriate medical professional.
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