Shipping to the U.S. has not yet resumed. We are awaiting final confirmation from Qantas Airways’ legal team that it is safe to uplift parcels to the U.S.

This delay is affecting all international shipments into the U.S. until airlines and postal services receive legal clearance. Unfortunately, this is outside of our control.

Australia Post, who work in partnership with Qantas for international freight, has announced it expects to resume U.S. services by 25 September. On this basis, we remain confident that parcels will be uplifted within September and possibly within the coming days.

Orders can still be placed as usual. Our team will pack your items and dispatch them to our postal agent, where they will be securely held until Qantas resumes services.

We sincerely appreciate your patience, trust, and continued support during this frustrating time.

For any questions or concerns, please don’t hesitate to contact us via email or phone.

Many thanks, the Inhouse Pharmacy Team.

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Visiocare (Ciclosporin) 2mg/g Visiocare general information What is Visiocare used for? Visiocare eye ointment 2mg/g is a topical ophthalmic medication for dogs, used to treat conditions that are thought to be immune mediated due to an autoimmune disease, where the immune system attacks the body’s own tissues. Keratoconjunctivitis sicca (KCS), also called dry eye, is a lack of tear production, and the most common cause of this condition is damage to the tear producing lachrymal glands by the immune system. The result is that the tear film, which is a fat and mucus based protective film does not fully cover the eye, causing the eye to dry out causing pain and inflammation. Symptoms of KCS include itching, burning, irritation, and photophobia (extreme sensitivity to light). Chronic superficial keratitis (CSK) is also an immune mediated eye condition in dogs that is most common in German Shepherds but can occur in all breeds of dog. CKS is chronic inflammation of the cornea and sclera (white of the eye), which become pigmented and infiltrated with blood vessels and immune cells and can lead to blindness. The pathogenesis of both KCS and CSK are thought to be influenced by ultraviolet radiation, particularly at high elevation, where UV is stronger. Visiocare eye ointment 2mg/g reduce swelling, redness, discomfort and irritation of the eyes associated with inflammation. It also increases tear production to improve symptoms of dry eyes. How does Visiocare work? Visiocare eye ointment 2mg/g contains ciclosporin, an immunosuppressant that is used to treat immune-mediated eye conditions in dogs. Cyclosporin in Visiocare eye ointment targets specific immune cells involved in the allergic and immune reaction. It works by blocking the action of T lymphocytes by inhibiting the production of certain inflammatory cytokines, specifically interleukin-2 that is produced in response to antigen activation of T lymphocytes, which in the case of autoimmune diseases are autoantigens (antigens against self). Cyclosporin in Visiocare eye ointment also blocks proliferation of these activated T-cells but has no effect on other cells of the immune system. By blocking immune mediated cell damage, Cyclosporin in Visiocare eye ointment reduces pain and inflammation associated with these eye conditions and reduces damage to the lachrymal glands, which increases tear production. Visiocare eye ointment uses microemulsification technology, which is a mixture of oil and water in combination with a surfactant, which allows the ointment to spread more readily over the surface of the eye to increase cyclosporin bioavailability. What does Visiocare contain? Visiocare eye ointment 2mg/g contains the active ingredient cyclosporin, an immunosuppressant that is used to treat immune-mediated eye conditions in dogs. It also contains emulsifier. Treating immune-mediated eye conditions with Visiocare Visiocare eye ointment 2mg/g contains cyclosporin, an immunosuppressant that is used to treat immune-mediated eye conditions in dogs. Keratoconjunctivitis sicca (KCS), also called dry eye, caused by a lack of tear production, due to damage to the tear producing lachrymal glands. The result is that the tear film, which is a fat and mucus based protective film does not fully cover the eye, causing the eye to dry out. Symptoms of KCS include itching, burning, irritation, and photophobia (extreme sensitivity to light). Chronic superficial keratitis (CSK) is chronic inflammation of the cornea and sclera (white of the eye), which become pigmented and infiltrated with blood vessels and immune cells and can lead to blindness. Cyclosporin in Visiocare eye ointment targets specific immune cells involved in the allergic and immune reaction, and the production of certain inflammatory cytokines, specifically interleukin-2 that is produced by antigen activated T lymphocytes. Cyclosporin in Visiocare eye ointment also blocks proliferation of these activated T-cells but has no effect on other cells of the immune system. Visiocare eye ointment 2mg/g reduce swelling, redness, discomfort and irritation of the eyes associated with inflammation. It also increases tear production to improve symptoms of dry eyes. What are the side effects of Visiocare? The most commonly reported side effects when taking Visiocare eye ointment 2mg/g include redness and irritation at the site of application, causing your dog to blink and rub the eye. When should Visiocare not be used? You should not use give Visiocare eye ointment 2mg/g to your dog if your dog: is allergic to cyclosporin or any ingredients in Visiocare is pregnant or lactating has a fungal or viral infection as Visiocare eye ointment may worsen or prolong the infection has corneal ulcers as Visiocare eye ointment may delay healing are taking medicines that interact with Visiocare like topical coticorsteroids, without discussion and instruction from your veterinarian How should Visiocare be taken? You should apply your Visiocare eye ointment 2mg/g to your dogs’ eye by tilting the head back and squeezing a small strip of ointment into the conjunctival sac. You should apply Visiocare eye ointment to your dog’s eye twice daily every 12 hours, morning and evening and for long term as it will help improve symptoms but will not cure your dog’s condition. How long should you use Visiocare? You should apply Visiocare eye ointment to your dog’s eye long term as it will help improve symptoms but will not cure your dog’s condition. Missed dose of Visiocare If you miss a dose of Visiocare eye ointment 2mg/g apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose. How should Visiocare be stored? You should store your Visiocare eye ointment 2mg/g below 25°C in a cool dry place.
Glyciphage 500mg (Metformin) Glyciphage general information What is Glyciphage used for? Glyciphage tablets 500mg are an oral diabetes medication that is used to control blood sugar levels in people with type-2 diabetes mellitus (also called non insulin-dependent diabetes or maturity onset diabetes) who are unable to achieve adequate glycaemic control (normal blood sugar levels) with diet and exercise alone, which is a particular problem in overweight people. Glyciphage tablets 500mg can be used as first time treatment for newly diagnosed diabetics, or for patients who are not responding to an alternative medication, and can be used either alone or in combination with another oral antihyperglycaemic medication (lowers blood sugar). In some cases Glyciphage is used in conjunction with insulin in type 1 diabetes (also called insulin -dependent diabetes), where insulin alone is not enough to control blood sugar levels. How does Glyciphage work? Glyciphage tablets 500mg contain the active ingredient Metformin hydrochloride, which is an oral antihyperglycaemic medication belonging to the biguanide group of drugs. Metformin in Glyciphage tablets 500mg controls blood glucose (sugar) by lowering levels of glucose after a meal (posprandial) as well as keeping levels normal between meals (basal levels), by helping the body respond to insulin without increasing insulin production. Metformin in Glyciphage tablets 500mg works using three different mechanisms: decreasing glucose production in the liver, which is normally switched off when blood glucose levels are high enough; increasing sensitivity to insulin in fat and muscle tissue, where excess glucose is removed from the blood and stored; reducing absorption of glucose by the intestines form the diet. Maintaining glycaemic control with Glyciphage tablets 500mg reduces risk of serious health complications associated with diabetes, including diabetic retinopathy (damage to the retina in the eye with loss of vision), diabetic neuropathy (nerve damage) and diabetic nephropathy (kidney damage). What does Glyciphage contain? Glyciphage tablets 500mg contain the active ingredient metformin, which is an oral antihyperglycaemic medication used to control blood sugar levels in people with type-2 diabetes mellitus. Treating type 2 diabetes with Glyciphage Glyciphage tablets 500mg contain Metformin, which is an oral antihyperglycaemic medication that is used to control blood sugar levels in people with type-2 diabetes mellitus (also called non insulin-dependent diabetes or maturity onset diabetes) who are unable to achieve adequate glycaemic control (normal blood sugar levels) with diet and exercise alone, which is a particular problem in overweight people. Metformin in Glyciphage tablets 500mg lowers blood sugar after a meal (posprandial) as well as keeping levels normal between meals (basal levels), by helping the body respond to insulin without increasing insulin production, using three different mechanisms: decreasing glucose production in the liver, which is normally switched off when blood glucose levels are high enough; increasing sensitivity to insulin in fat and muscle tissue, where excess glucose is removed from the blood and stored; reducing absorption of glucose by the intestines form the diet. Maintaining glycaemic control with Glyciphage tablets 500mg reduces risk of serious health complications associated with diabetes, including diabetic retinopathy (damage to the retina in the eye with loss of vision), diabetic neuropathy (nerve damage) and diabetic nephropathy (kidney damage). What are the side effects of Glyciphage? The most commonly reported side effects when taking Glyciphage tablets 500mg include: gastrointestinal symptoms, such as diarrhoea, nausea, vomiting, which are usually mild and resolve spontaneously during continued treatment; metallic taste in the mouth; and skin rash. A rare and potentially life threatening side effect is lactic acidosis (a build up of lactic acid in the blood) that can occur due to accumulation of metformin, particularly if you are taking high doses of metformin above 2000mg per day, have kidney problems, drink excessive amounts of alcohol, are elderly. When should Glyciphage not be used? You should not use Glyciphage if you: are allergic to metformin or any other biguanide or any ingredients in Glyciphage tablets 500mg are pregnant or are breastfeeding without discussion with your doctor have liver or kidney disease have a conditions affecting renal function, like dehydration, severe infection or shock have diabetic ketoacidosis, diabetic precoma have acute or chronic disease which may cause tissue hypoxia such as heart failure, recent myocardial infarction, respiratory failure, pulmonary embolism, shock, acute significant blood loss, sepsis, gangrene, pancreatitis have a history of lactic acidosis have a problem with alcohol are taking medications that may interact with Glyciphage tablets 500mg including: cimetidine for reflux and ulcers, medications for high blood pressure and heart conditions like nifedipine, beta-blockers, diuretics, other diabetes medications like sulfonylureas and repaglinide, corticosteroids such as prednisone, cortisone, anticoagulants undergoing radiological treatment with intravascular iodinated contrast agents which may lead to renal failure, resulting in metformin accumulation and a risk of lactic acidosis What medications interact with Glyciphage Several medications interact with Glyciphage and should either not be taken while you are taking Glyciphage or only after discussion and instruction from your doctor: Drugs that interact with Glyciphage to increase side effects: other diabetes medications like sulfonylureas and repaglinide, ACE inhibitors for high blood pressure, corticosteroids such as prednisone, cortisone Drugs that affect Glyciphage: cimetidine for reflux and ulcers, medications for high blood pressure and heart conditions like nifedipine, beta-blockers, diuretics , thyroid medicines Drugs that are affected by Glyciphage: anticoagulants How should Glyciphage be taken? You should take your Glyciphage tablets 500mg with a glass of water and with food. The dose you take and how often should be as recommended by your doctor. The usual starting dose is one tablet once, twice or 3 times daily during or immediately after a meal, to reduce stomach effects. You will have your blood sugar levels monitored and your dose may be adjusted after a few weeks, depending on how well your blood sugar levels are controlled. You should continue to take your Metformin tablets 500mg for as long as recommended by your doctor, which may be for long periods. How long should you take Glyciphage? You should continue to take your Glyciphage tablets 500mg for as long as recommended by your doctor, which may be for long periods. Missed dose of Glyciphage If you miss a dose of Glyciphage take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Glyciphage be stored? You should store your Glyciphage tablets 500mg below 25°C in a cool dry place out of direct sunlight.
Myloc CR 95mg 90 Tablets/Pack Myloc CR general information What is Myloc CR used for? Myloc CR tablets 95mg are used to treat a variety of conditions of the cardiovascular system including, control of hypertension (high blood pressure) by lowering blood pressure to reduce the risk of complications such as stroke and heart attack; management of angina (chest pain) in patients with heart disease; long-term prevention of myocardial infarction (heart attack); treatment of heart failure to improve survival and quality of life; and control of most forms of arrhythmias and dysrhythmias (irregular heart beat or rhythm) and palpitations. Myloc CR tablets are also used for preventing migraine, and as a supplementary treatment for hyperthyroidism (overactive thyroid). Myloc CR tablets work through a common mechanism in several different body systems to manage the condition and relieve symptoms by reducing heart rate (pulse), workload on the heart (force needed to pump) and oxygen demand by the heart, which increases blood flow and lowers blood pressure. How does Myloc CR work? Myloc CR tablets 95mg contain metoprolol, which is a beta-blocker or selective beta 1-receptor antagonist and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works via beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are reduced or inhibited by metoprolol in Myloc CR tablets, to slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. Since beta-receptors are found in many tissues, particularly the heart, kidneys, vascular smooth muscle in blood vessel walls, lung, skeletal muscle and liver, all short-term and long-term symptom relief due to taking Myloc CR, is based on blocking beta-receptors in the target tissue. Myloc CR tablets are formulated for controlled release so that metoprolol is that released in a sustained and time controlled manner, to ensure a more even effect over 24 hours, which provides better symptom relief with fewer side effects. What does Myloc CR contain? Myloc CR tablets 95mg contain the active ingredient metoprolol succinate, a beta-blocker used to treat variety of conditions of the cardiovascular system and other conditions. They also contain ethylcellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, microcrystalline cellulose, paraffin, polyethylene glycol, silicon dioxide, sodium stearyl fumarate, titanium dioxide What Myloc CR doses are available? Myloc CR tablets are available to order and buy online from Inhouse Pharmacy in doses of 23.75mg, 47.5mg, 95mg and 190mg Treating blood pressure (hypertension) with Myloc CR Myloc CR tablets 95mg contain metoprolol, which is a beta-blocker and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Myloc CR tablets 95mg are used to treat high blood pressure (hypertension) by widening blood vessels, reducing heart rate (number of heart beats) and reducing the force of the heart contraction. These actions lower blood pressure and help the heart to cope better, reducing symptoms of breathlessness on exertion and reducing the risk of complications such as stroke and heart attack, due to high blood pressure. Treating heart disease with Myloc CR Myloc CR tablets 95mg contain metoprolol, which is a beta-blocker and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Myloc CR tablets 95mg are used to treat a variety of conditions of the cardiovascular system to improve survival, reduce symptoms and improve the quality of life in patients with heart disease, including, control of hypertension (high blood pressure), management of angina (chest pain); long-term prevention of myocardial infarction (heart attack) and treatment of heart failure. What are the side effects of Myloc CR? The mot common side effects reported while taking Myloc CR tablets 95mg include: tiredness, dizziness when you change position, cold hands and feet, nausea, vomiting, diarrhoea, stomach pain, constipation, palpitations, weight gain, sleep disturbances or nightmares, shortness of breath on exertion, mood changes or confusion, dry eyes. When should Myloc CR not be used? You should not use Myloc CR tablets 95mg if you: are allergic to metoprolol or any other ingredients in Myloc CR tablets have a history of obstructive lung disorder, bronchial asthma or bronchospasm are diabetic and taking hypoglycaemic therapy, without discussion with your doctor as metoprolol may prolong the hypoglycaemic response to insulin are pregnant or breast feeding, without discussion with your doctor have, poor peripheral blood circulation, uncontrolled heart failure, low blood pressure (hypotension), have a phaeochromocytoma (a rare tumour of the adrenal gland) which is not already being treated with other medicines have certain other heart problems are taking medication that may interact with Myloc CR tablets, including: other medicines for high blood pressure; angina or an irregular heart beat such as calcium channel blockers (diltiazem, verapamil, and nifedipine), antiarrhythmics (disopyramide) digoxin, clonidine, hydralazine; other beta-blockers, including eye drops; the antibiotic rifampicin; adrenaline for emergencies like anaphylaxis; monoamine oxidase inhibitors; antiinflammatories like ibuprofen or indomethacin; cimetidine for reflux and ulcers; chlorpromazine for psychiatric disorders. How should Myloc CR be taken? You should take your Myloc CR tablets 95mg with a glass of water, swallowed whole, with or without food, usually once daily either morning or evening, but at the same time each day. You should take Myloc CR tablets according to your doctor’s recommendations and the number of capsules you take each day, how often you take them and for how long depends on the condition you are being treated for. The dose you are taking may be increased by your doctor. You must take your capsules every day, as instructed and if you are advised to stop taking them, withdrawal should be gradual and treatment should not be discontinued abruptly. How long should you take Myloc CR? You should take your Myloc CR tablets 95mg for as long as your doctor recommendations, which may be for a few days, weeks, months or longer depending on the condition you are being treated for. Missed dose of Myloc CR If you miss a dose of Myloc CR tablets 95mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Myloc CR be stored? You should store your Myloc CR tablets 95mg in a cool dry place below 25°C, protected from light and moisture.
Phenergan 25mg (Promethazine) Phenergan general information What is Phenergan used for? Phenergan tablets 25mg are used to treat a variety of allergic conditions, including allergic contact dermatitis, allergic reactions to drugs, hives (urticaria), and bites and stings, to relieve symptoms of redness, swelling and itching of the skin; also to relieve upper respiratory tract symptoms of allergic rhinitis, including nasal congestion, runny itchy nose and sneezing, caused by seasonal allergies like hayfever. Phenergan tablets 25mg are also used as an antiemetic to reduce nausea and vomiting due to several conditions including postoperative vomiting, irradiation sickness, drug-induced nausea and motion sickness. Phenergan tablets 25mg have sedative properties, which can be used to help with management of the symptoms of measles and chicken pox; also for short-term sedation. How does Phenergan work? Phenergan tablets 25mg contain promethazine, an antihistamine belonging to phenothiazine group of drugs that also has antiemetic (prevents nausea) and sedative properties. Histamine is a chemical released from mast cells, (cells involved in allergies) as part of the body’s defence mechanism during an allergic reaction. Histamine and binds to H1 receptors in small blood vessels causing them to leak, allowing white blood cells and blood proteins into the tissues. These infiltrating cells produce inflammatory chemicals (prostaglandins and leukotrienes) that cause tissue swelling and irritation, which are symptoms of an allergic reaction. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors and blocking the action of histamine without blocking its secretion. This action blocks histamine-mediated allergic reactions, relieving symptoms in the upper respiratory tract like nasal congestion, runny itchy nose and sneezing, and in the skin like redness, swelling and itching. Promethazine in Phenergan tablets 25mg also acts on the central nervous system (CNS). Some brain neurones (nerve cells) produce histamine and the action of histamine in the brain is involved in stress and anxiety reactions. Blocking these brain histamine receptors is thought to be responsible for causing sedation. The same CNS mechanism is also responsible for the anti-emetic effect of Phenergan tablets 25mg. Motion sickness is caused by conflicting information being received by the brain from the eyes and the vestibular system in the inner ear; messages sent by the ear suggest motion, whereas the messages sent by the eye suggest that the body is still. The conflicting information received into the brain stimulates the vomiting centre of the brain to induce the vomiting reflex. Promethazine in Phenergan tablets 25mg binds to histamine receptors on cells of the vestibular apparatus of the inner ear and is also thought to bind to histamine receptors on nerve cells in the brain to block the transmission of nerve impulses from the inner ear to the vomiting center in the brain, which in turn prevents transmission of nerve signals from the brain to receptors in the stomach, so that the vomiting reflex is blocked. What does Phenergan contain? Phenergan tablets 25mg contain the active ingredient promethazine hydrochloride, an antihistamine belonging to phenothiazine group of drugs that also has antiemetic (prevents nausea) and sedative properties. They also contain lactose, starch maize, povidone, magnesium stearate, hypromellose, macrogol 200, blue opaspray. Treating allergy with Phenergan Phenergan tablets 25mg contain the antihistamine promethazine, which is used to relieve symptoms of allergy in several allergic conditions, including allergic contact dermatitis, allergic reactions to drugs, hives (urticaria), bites and stings; also allergic rhinitis caused by seasonal allergies like hayfever. Histamine is a chemical released from mast cells, (cells involved in allergies) as part of the body’s defence mechanism during an allergic reaction and binds to H1 receptors in small blood vessels causing them to leak, allowing white blood cells and blood proteins into the tissues. These infiltrating cells produce inflammatory chemicals (prostaglandins and leukotrienes) that cause tissue swelling and irritation, which are symptoms of an allergic reaction. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors and blocking the action of histamine without blocking its secretion. This action blocks histamine-mediated allergic reactions, relieving symptoms in the upper respiratory tract like nasal congestion, runny itchy nose and sneezing, and in the skin like redness, swelling and itching. Treating motion sickness with Phenergan Phenergan tablets 25mg contain promethazine, an antihistamine that is used to control the nausea and vomiting associated with motion sickness caused by all forms of travel including, air, sea train or car travel. The inner ear contains the vestibular apparatus, comprising the membranous labyrinth structures of the cochlea and semicircular canals, where motion or changes in the body’s position is detected and continual information about body position is transmitted to the brain. Motion causes the endolymph (fluid that fills the inner ear) to trigger electrical signals via special sensory cells sending nerve impulses via neurotransmitters (chemicals that allow nerve cells to communicate) along the auditory nerve to the brain to be interpreted. Motion sickness is caused by conflicting information being received by the brain from the eyes and the vestibular system; messages sent by the ear suggest motion, whereas the messages sent by the eye suggest that the body is still. The conflicting information received into the brain stimulates the area postrema or vomiting centre of the brain to induce the vomiting reflex. Promethazine in Phenergan tablets 25mg binds to histamine receptors on cells of the vestibular apparatus of the inner ear and is also thought to bind to histamine receptors on nerve cells in the brain and this blocks the transmission of nerve impulses from the inner ear to the vomiting center in the brain, which in turn prevents transmission of nerve signals from the brain to receptors in the stomach, so that the vomiting reflex is blocked. Phenergan tablets 25mg are also used to reduce nausea and vomiting due to several conditions including postoperative vomiting, irradiation sickness and drug-induced nausea. Phenergan for sedation Phenergan tablets 25mg contain promethazine, an antihistamine that has sedating properties. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors in various parts of the body including the brain. Some brain neurones (nerve cells) produce histamine and the action of histamine in the brain is involved in stress and anxiety reactions. Blocking these brain histamine receptors is thought to be responsible for causing sedation. What are the side effects of Phenergan? The most commonly reported side effects when taking Phenergan tablets 25mg include: dry mouth, gastro-intestinal disturbances (diarrhoea, constipation, nausea, vomiting or abdominal pain) loss of appetite, tiredness, sleepiness, restlessness, dizziness, blurred vision. When should Phenergan not be used? You should not use Phenergan tablets 25mg if you: are allergic to promethazine or any ingredients in Phenergan are allergic to sulphites, benzoates or phenothiazines are pregnant or are breastfeeding have had jaundice induced by other phenothiazine derivatives are taking medicines that interact with Phenergan, including: monoamine oxidase inhibitors (MAOIs) (up to 14 days previously), tricyclic antidepressants, sedatives and hypnotics, opioid analgesics, barbiturates Phenergan tablets 25mg should not be used for children under 2 years or for anyone in a coma. What medications interact with Phenergan? Several medications interact with Phenergan tablets 25mg to increase side effects and can cause a serious reaction and should either not be taken while you are taking Phenergan or only after discussion and instruction from your doctor: including: monoamine oxidase inhibitors (MAOIs) (up to 14 days previously, tricyclic antidepressants, sedatives and hypnotics, opioid analgesics, barbiturates. How should Phenergan be taken? You should take your Phenergan tablets 25mg swallowed whole with a glass of water. The dose you take and how often depends on what you are being treated for and your doctor’s recommendation. For allergy and sedation you should take your Phenergan tablets 25mg at night. For travel sickness you should take one tablet the night before travel and you can take another dose the next day, provided 6-8 hours has elapsed. For nausea and vomiting you should take your Phenergan tablets 25mg every 4 to 6 hours as recommended by your doctor. You should continue to take your Phenergan tablets 25mg for as long as your symptoms persist, or as recommended by your doctor but for no longer than 10 consecutive days. How long should you take Phenergan? You should continue to take your Phenergan tablets 25mg for as long as your symptoms persist, or as recommended by your doctor but for no longer than 10 consecutive days. Missed dose of Phenergan If you miss a dose of Phenergan tablets 25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. How should Phenergan be stored? You should store your Phenergan below 25°C in a cool dry place.
Muply (Mupirocin 2%) Ointment Muply general information What is Muply used for? Muply ointment is a topical treatment for a variety of primary bacterial skin infections, including, impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root ; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also used to treat secondary infections that occur in damaged skin, for example due to eczema, psoriasis, atopic dermatitis, herpes (cold sores), epidermolysis bullosa (an inherited diseases characterised by blistering lesions on the skin and mucous membranes), icthyosis (genetic skin disorders that cause dry, fragile skin); also for treatment of infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites, as well as to prevent the development of infection and help wound healing. How does Muply work? Muply ointment contains mupirocin, an antibiotic that has very potent bactericidal activity, and is used as a topical treatment for a variety of primary skin infections; and secondary infections that occur in damaged skin and in skin lesions. Mupirocin in Muply ointment inhibits protein and RNA synthesis in susceptible bacteria, which include staphylococci, streptococci, and Haemophilus influenza. This action of mupirocin in Muply ointment blocks growth and replication of the susceptible bacteria, and prevents the spread of the infection. What does Muply contain? Muply ointment contains the active ingredient mupirocin 2%, a topical antibiotic used to treat variety of skin infections. Treating skin infections with Muply Muply ointment contains mupirocin, an antibiotic that is used as a topical treatment for a variety of skin infections. Skin infections that Muply ointment is used for include impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also effective against secondary infections that occur in damaged skin due to eczema, psoriasis, atopic dermatitis, herpes and genetic skin disorders that cause dry, fragile skin; as well as for infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites; and to prevent the development of infection and help wound healing. Mupirocin in Muply ointment inhibits the protein and RNA synthesis in susceptible bacteria, which blocks growth and replication of these bacteria and prevents the spread of the infection. What are the side effects of Muply? The most commonly reported side effects when taking Muply include itching, dryness, burning, redness, stinging, pain or swelling. When should Muply not be used? You should not use Muply ointment if you: are allergic to mupirocin or any ingredients in Muply have an eye or nose infection, as Muply ointment is suitable only for skin infections How should Muply be used? You should apply your Muply ointment to the affected area three times each day. Squeeze a small amount onto your finger tip and rub in gently; always wash your hands before and after applying the ointment and avoid contact with the eyes. Your doctor may recommend applying a gauze to the infected area over the ointment. You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days. How long should you use Muply? You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days. Missed dose of Muply If you miss a dose of Muply ointment apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose. How should Muply be stored? You should store your Muply ointment below 25°C in a cool dry place; do not freeze the ointment.

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Visiocare (Ciclosporin) 2mg/g

Visiocare general information

What is Visiocare used for?

Visiocare eye ointment 2mg/g is a topical ophthalmic medication for dogs, used to treat conditions that are thought to be immune mediated due to an autoimmune disease, where the immune system attacks the body’s own tissues. Keratoconjunctivitis sicca (KCS), also called dry eye, is a lack of tear production, and the most common cause of this condition is damage to the tear producing lachrymal glands by the immune system. The result is that the tear film, which is a fat and mucus based protective film does not fully cover the eye, causing the eye to dry out causing pain and inflammation. Symptoms of KCS include itching, burning, irritation, and photophobia (extreme sensitivity to light). Chronic superficial keratitis (CSK) is also an immune mediated eye condition in dogs that is most common in German Shepherds but can occur in all breeds of dog. CKS is chronic inflammation of the cornea and sclera (white of the eye), which become pigmented and infiltrated with blood vessels and immune cells and can lead to blindness. The pathogenesis of both KCS and CSK are thought to be influenced by ultraviolet radiation, particularly at high elevation, where UV is stronger. Visiocare eye ointment 2mg/g reduce swelling, redness, discomfort and irritation of the eyes associated with inflammation. It also increases tear production to improve symptoms of dry eyes.

How does Visiocare work?

Visiocare eye ointment 2mg/g contains ciclosporin, an immunosuppressant that is used to treat immune-mediated eye conditions in dogs. Cyclosporin in Visiocare eye ointment targets specific immune cells involved in the allergic and immune reaction. It works by blocking the action of T lymphocytes by inhibiting the production of certain inflammatory cytokines, specifically interleukin-2 that is produced in response to antigen activation of T lymphocytes, which in the case of autoimmune diseases are autoantigens (antigens against self). Cyclosporin in Visiocare eye ointment also blocks proliferation of these activated T-cells but has no effect on other cells of the immune system. By blocking immune mediated cell damage, Cyclosporin in Visiocare eye ointment reduces pain and inflammation associated with these eye conditions and reduces damage to the lachrymal glands, which increases tear production. Visiocare eye ointment uses microemulsification technology, which is a mixture of oil and water in combination with a surfactant, which allows the ointment to spread more readily over the surface of the eye to increase cyclosporin bioavailability.

What does Visiocare contain?

Visiocare eye ointment 2mg/g contains the active ingredient cyclosporin, an immunosuppressant that is used to treat immune-mediated eye conditions in dogs. It also contains emulsifier.

Treating immune-mediated eye conditions with Visiocare

Visiocare eye ointment 2mg/g contains cyclosporin, an immunosuppressant that is used to treat immune-mediated eye conditions in dogs. Keratoconjunctivitis sicca (KCS), also called dry eye, caused by a lack of tear production, due to damage to the tear producing lachrymal glands. The result is that the tear film, which is a fat and mucus based protective film does not fully cover the eye, causing the eye to dry out. Symptoms of KCS include itching, burning, irritation, and photophobia (extreme sensitivity to light). Chronic superficial keratitis (CSK) is chronic inflammation of the cornea and sclera (white of the eye), which become pigmented and infiltrated with blood vessels and immune cells and can lead to blindness. Cyclosporin in Visiocare eye ointment targets specific immune cells involved in the allergic and immune reaction, and the production of certain inflammatory cytokines, specifically interleukin-2 that is produced by antigen activated T lymphocytes. Cyclosporin in Visiocare eye ointment also blocks proliferation of these activated T-cells but has no effect on other cells of the immune system. Visiocare eye ointment 2mg/g reduce swelling, redness, discomfort and irritation of the eyes associated with inflammation. It also increases tear production to improve symptoms of dry eyes.

What are the side effects of Visiocare?

The most commonly reported side effects when taking Visiocare eye ointment 2mg/g include redness and irritation at the site of application, causing your dog to blink and rub the eye.

When should Visiocare not be used?

You should not use give Visiocare eye ointment 2mg/g to your dog if your dog:

is allergic to cyclosporin or any ingredients in Visiocare
is pregnant or lactating
has a fungal or viral infection as Visiocare eye ointment may worsen or prolong the infection
has corneal ulcers as Visiocare eye ointment may delay healing
are taking medicines that interact with Visiocare like topical coticorsteroids, without discussion and instruction from your veterinarian

How should Visiocare be taken?

You should apply your Visiocare eye ointment 2mg/g to your dogs’ eye by tilting the head back and squeezing a small strip of ointment into the conjunctival sac. You should apply Visiocare eye ointment to your dog’s eye twice daily every 12 hours, morning and evening and for long term as it will help improve symptoms but will not cure your dog’s condition.

How long should you use Visiocare?

You should apply Visiocare eye ointment to your dog’s eye long term as it will help improve symptoms but will not cure your dog’s condition.

Missed dose of Visiocare

If you miss a dose of Visiocare eye ointment 2mg/g apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose.

How should Visiocare be stored?

You should store your Visiocare eye ointment 2mg/g below 25°C in a cool dry place.

Glyciphage 500mg (Metformin)

Glyciphage general information

What is Glyciphage used for?

Glyciphage tablets 500mg are an oral diabetes medication that is used to control blood sugar levels in people with type-2 diabetes mellitus (also called non insulin-dependent diabetes or maturity onset diabetes) who are unable to achieve adequate glycaemic control (normal blood sugar levels) with diet and exercise alone, which is a particular problem in overweight people. Glyciphage tablets 500mg can be used as first time treatment for newly diagnosed diabetics, or for patients who are not responding to an alternative medication, and can be used either alone or in combination with another oral antihyperglycaemic medication (lowers blood sugar). In some cases Glyciphage is used in conjunction with insulin in type 1 diabetes (also called insulin -dependent diabetes), where insulin alone is not enough to control blood sugar levels.

How does Glyciphage work?

Glyciphage tablets 500mg contain the active ingredient Metformin hydrochloride, which is an oral antihyperglycaemic medication belonging to the biguanide group of drugs. Metformin in Glyciphage tablets 500mg controls blood glucose (sugar) by lowering levels of glucose after a meal (posprandial) as well as keeping levels normal between meals (basal levels), by helping the body respond to insulin without increasing insulin production. Metformin in Glyciphage tablets 500mg works using three different mechanisms: decreasing glucose production in the liver, which is normally switched off when blood glucose levels are high enough; increasing sensitivity to insulin in fat and muscle tissue, where excess glucose is removed from the blood and stored; reducing absorption of glucose by the intestines form the diet. Maintaining glycaemic control with Glyciphage tablets 500mg reduces risk of serious health complications associated with diabetes, including diabetic retinopathy (damage to the retina in the eye with loss of vision), diabetic neuropathy (nerve damage) and diabetic nephropathy (kidney damage).

What does Glyciphage contain?

Glyciphage tablets 500mg contain the active ingredient metformin, which is an oral antihyperglycaemic medication used to control blood sugar levels in people with type-2 diabetes mellitus.

Treating type 2 diabetes with Glyciphage

Glyciphage tablets 500mg contain Metformin, which is an oral antihyperglycaemic medication that is used to control blood sugar levels in people with type-2 diabetes mellitus (also called non insulin-dependent diabetes or maturity onset diabetes) who are unable to achieve adequate glycaemic control (normal blood sugar levels) with diet and exercise alone, which is a particular problem in overweight people. Metformin in Glyciphage tablets 500mg lowers blood sugar after a meal (posprandial) as well as keeping levels normal between meals (basal levels), by helping the body respond to insulin without increasing insulin production, using three different mechanisms: decreasing glucose production in the liver, which is normally switched off when blood glucose levels are high enough; increasing sensitivity to insulin in fat and muscle tissue, where excess glucose is removed from the blood and stored; reducing absorption of glucose by the intestines form the diet. Maintaining glycaemic control with Glyciphage tablets 500mg reduces risk of serious health complications associated with diabetes, including diabetic retinopathy (damage to the retina in the eye with loss of vision), diabetic neuropathy (nerve damage) and diabetic nephropathy (kidney damage).

What are the side effects of Glyciphage?

The most commonly reported side effects when taking Glyciphage tablets 500mg include: gastrointestinal symptoms, such as diarrhoea, nausea, vomiting, which are usually mild and resolve spontaneously during continued treatment; metallic taste in the mouth; and skin rash. A rare and potentially life threatening side effect is lactic acidosis (a build up of lactic acid in the blood) that can occur due to accumulation of metformin, particularly if you are taking high doses of metformin above 2000mg per day, have kidney problems, drink excessive amounts of alcohol, are elderly.

When should Glyciphage not be used?

You should not use Glyciphage if you:

are allergic to metformin or any other biguanide or any ingredients in Glyciphage tablets 500mg
are pregnant or are breastfeeding without discussion with your doctor
have liver or kidney disease
have a conditions affecting renal function, like dehydration, severe infection or shock
have diabetic ketoacidosis, diabetic precoma
have acute or chronic disease which may cause tissue hypoxia such as heart failure, recent myocardial infarction, respiratory failure, pulmonary embolism, shock, acute significant blood loss, sepsis, gangrene, pancreatitis
have a history of lactic acidosis
have a problem with alcohol
are taking medications that may interact with Glyciphage tablets 500mg including: cimetidine for reflux and ulcers, medications for high blood pressure and heart conditions like nifedipine, beta-blockers, diuretics, other diabetes medications like sulfonylureas and repaglinide, corticosteroids such as prednisone, cortisone, anticoagulants
undergoing radiological treatment with intravascular iodinated contrast agents which may lead to renal failure, resulting in metformin accumulation and a risk of lactic acidosis

What medications interact with Glyciphage

Several medications interact with Glyciphage and should either not be taken while you are taking Glyciphage or only after discussion and instruction from your doctor:

Drugs that interact with Glyciphage to increase side effects: other diabetes medications like sulfonylureas and repaglinide, ACE inhibitors for high blood pressure, corticosteroids such as prednisone, cortisone
Drugs that affect Glyciphage: cimetidine for reflux and ulcers, medications for high blood pressure and heart conditions like nifedipine, beta-blockers, diuretics , thyroid medicines
Drugs that are affected by Glyciphage: anticoagulants

How should Glyciphage be taken?

You should take your Glyciphage tablets 500mg with a glass of water and with food. The dose you take and how often should be as recommended by your doctor. The usual starting dose is one tablet once, twice or 3 times daily during or immediately after a meal, to reduce stomach effects. You will have your blood sugar levels monitored and your dose may be adjusted after a few weeks, depending on how well your blood sugar levels are controlled. You should continue to take your Metformin tablets 500mg for as long as recommended by your doctor, which may be for long periods.

How long should you take Glyciphage?

You should continue to take your Glyciphage tablets 500mg for as long as recommended by your doctor, which may be for long periods.

Missed dose of Glyciphage

If you miss a dose of Glyciphage take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Glyciphage be stored?

You should store your Glyciphage tablets 500mg below 25°C in a cool dry place out of direct sunlight.

Myloc CR 95mg 90 Tablets/Pack

Myloc CR general information

What is Myloc CR used for?

Myloc CR tablets 95mg are used to treat a variety of conditions of the cardiovascular system including, control of hypertension (high blood pressure) by lowering blood pressure to reduce the risk of complications such as stroke and heart attack; management of angina (chest pain) in patients with heart disease; long-term prevention of myocardial infarction (heart attack); treatment of heart failure to improve survival and quality of life; and control of most forms of arrhythmias and dysrhythmias (irregular heart beat or rhythm) and palpitations. Myloc CR tablets are also used for preventing migraine, and as a supplementary treatment for hyperthyroidism (overactive thyroid). Myloc CR tablets work through a common mechanism in several different body systems to manage the condition and relieve symptoms by reducing heart rate (pulse), workload on the heart (force needed to pump) and oxygen demand by the heart, which increases blood flow and lowers blood pressure.

How does Myloc CR work?

Myloc CR tablets 95mg contain metoprolol, which is a beta-blocker or selective beta 1-receptor antagonist and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Adrenaline works via beta-receptors in the heart to stimulate increased heart rate and constriction (narrowing) of blood vessels. These actions of adrenaline are reduced or inhibited by metoprolol in Myloc CR tablets, to slow heart rate, dilate (widen) blood vessels, lower blood pressure, and increase blood flow and oxygen to the heart. Since beta-receptors are found in many tissues, particularly the heart, kidneys, vascular smooth muscle in blood vessel walls, lung, skeletal muscle and liver, all short-term and long-term symptom relief due to taking Myloc CR, is based on blocking beta-receptors in the target tissue. Myloc CR tablets are formulated for controlled release so that metoprolol is that released in a sustained and time controlled manner, to ensure a more even effect over 24 hours, which provides better symptom relief with fewer side effects.

What does Myloc CR contain?

Myloc CR tablets 95mg contain the active ingredient metoprolol succinate, a beta-blocker used to treat variety of conditions of the cardiovascular system and other conditions. They also contain ethylcellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, microcrystalline cellulose, paraffin, polyethylene glycol, silicon dioxide, sodium stearyl fumarate, titanium dioxide

What Myloc CR doses are available?

Myloc CR tablets are available to order and buy online from Inhouse Pharmacy in doses of 23.75mg, 47.5mg, 95mg and 190mg

Treating blood pressure (hypertension) with Myloc CR

Myloc CR tablets 95mg contain metoprolol, which is a beta-blocker and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Myloc CR tablets 95mg are used to treat high blood pressure (hypertension) by widening blood vessels, reducing heart rate (number of heart beats) and reducing the force of the heart contraction. These actions lower blood pressure and help the heart to cope better, reducing symptoms of breathlessness on exertion and reducing the risk of complications such as stroke and heart attack, due to high blood pressure.

Treating heart disease with Myloc CR

Myloc CR tablets 95mg contain metoprolol, which is a beta-blocker and acts by blocking the action of chemicals called catecholamines, such as adrenaline (epinephrine), which are released by the adrenal glands in response to nerve stimulation during physical and mental stress. Myloc CR tablets 95mg are used to treat a variety of conditions of the cardiovascular system to improve survival, reduce symptoms and improve the quality of life in patients with heart disease, including, control of hypertension (high blood pressure), management of angina (chest pain); long-term prevention of myocardial infarction (heart attack) and treatment of heart failure.

What are the side effects of Myloc CR?

The mot common side effects reported while taking Myloc CR tablets 95mg include: tiredness, dizziness when you change position, cold hands and feet, nausea, vomiting, diarrhoea, stomach pain, constipation, palpitations, weight gain, sleep disturbances or nightmares, shortness of breath on exertion, mood changes or confusion, dry eyes.

When should Myloc CR not be used?

You should not use Myloc CR tablets 95mg if you:

are allergic to metoprolol or any other ingredients in Myloc CR tablets
have a history of obstructive lung disorder, bronchial asthma or bronchospasm
are diabetic and taking hypoglycaemic therapy, without discussion with your doctor as metoprolol may prolong the hypoglycaemic response to insulin
are pregnant or breast feeding, without discussion with your doctor
have, poor peripheral blood circulation, uncontrolled heart failure, low blood pressure (hypotension),
have a phaeochromocytoma (a rare tumour of the adrenal gland) which is not already being treated with other medicines
have certain other heart problems
are taking medication that may interact with Myloc CR tablets, including: other medicines for high blood pressure; angina or an irregular heart beat such as calcium channel blockers (diltiazem, verapamil, and nifedipine), antiarrhythmics (disopyramide) digoxin, clonidine, hydralazine; other beta-blockers, including eye drops; the antibiotic rifampicin; adrenaline for emergencies like anaphylaxis; monoamine oxidase inhibitors; antiinflammatories like ibuprofen or indomethacin; cimetidine for reflux and ulcers; chlorpromazine for psychiatric disorders.

How should Myloc CR be taken?

You should take your Myloc CR tablets 95mg with a glass of water, swallowed whole, with or without food, usually once daily either morning or evening, but at the same time each day. You should take Myloc CR tablets according to your doctor’s recommendations and the number of capsules you take each day, how often you take them and for how long depends on the condition you are being treated for. The dose you are taking may be increased by your doctor. You must take your capsules every day, as instructed and if you are advised to stop taking them, withdrawal should be gradual and treatment should not be discontinued abruptly.

How long should you take Myloc CR?

You should take your Myloc CR tablets 95mg for as long as your doctor recommendations, which may be for a few days, weeks, months or longer depending on the condition you are being treated for.

Missed dose of Myloc CR

If you miss a dose of Myloc CR tablets 95mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Myloc CR be stored?

You should store your Myloc CR tablets 95mg in a cool dry place below 25°C, protected from light and moisture.

Phenergan 25mg (Promethazine)

Phenergan general information

What is Phenergan used for?

Phenergan tablets 25mg are used to treat a variety of allergic conditions, including allergic contact dermatitis, allergic reactions to drugs, hives (urticaria), and bites and stings, to relieve symptoms of redness, swelling and itching of the skin; also to relieve upper respiratory tract symptoms of allergic rhinitis, including nasal congestion, runny itchy nose and sneezing, caused by seasonal allergies like hayfever. Phenergan tablets 25mg are also used as an antiemetic to reduce nausea and vomiting due to several conditions including postoperative vomiting, irradiation sickness, drug-induced nausea and motion sickness. Phenergan tablets 25mg have sedative properties, which can be used to help with management of the symptoms of measles and chicken pox; also for short-term sedation.

How does Phenergan work?

Phenergan tablets 25mg contain promethazine, an antihistamine belonging to phenothiazine group of drugs that also has antiemetic (prevents nausea) and sedative properties. Histamine is a chemical released from mast cells, (cells involved in allergies) as part of the body’s defence mechanism during an allergic reaction. Histamine and binds to H1 receptors in small blood vessels causing them to leak, allowing white blood cells and blood proteins into the tissues. These infiltrating cells produce inflammatory chemicals (prostaglandins and leukotrienes) that cause tissue swelling and irritation, which are symptoms of an allergic reaction. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors and blocking the action of histamine without blocking its secretion. This action blocks histamine-mediated allergic reactions, relieving symptoms in the upper respiratory tract like nasal congestion, runny itchy nose and sneezing, and in the skin like redness, swelling and itching. Promethazine in Phenergan tablets 25mg also acts on the central nervous system (CNS). Some brain neurones (nerve cells) produce histamine and the action of histamine in the brain is involved in stress and anxiety reactions. Blocking these brain histamine receptors is thought to be responsible for causing sedation. The same CNS mechanism is also responsible for the anti-emetic effect of Phenergan tablets 25mg. Motion sickness is caused by conflicting information being received by the brain from the eyes and the vestibular system in the inner ear; messages sent by the ear suggest motion, whereas the messages sent by the eye suggest that the body is still. The conflicting information received into the brain stimulates the vomiting centre of the brain to induce the vomiting reflex. Promethazine in Phenergan tablets 25mg binds to histamine receptors on cells of the vestibular apparatus of the inner ear and is also thought to bind to histamine receptors on nerve cells in the brain to block the transmission of nerve impulses from the inner ear to the vomiting center in the brain, which in turn prevents transmission of nerve signals from the brain to receptors in the stomach, so that the vomiting reflex is blocked.

What does Phenergan contain?

Phenergan tablets 25mg contain the active ingredient promethazine hydrochloride, an antihistamine belonging to phenothiazine group of drugs that also has antiemetic (prevents nausea) and sedative properties. They also contain lactose, starch maize, povidone, magnesium stearate, hypromellose, macrogol 200, blue opaspray.

Treating allergy with Phenergan

Phenergan tablets 25mg contain the antihistamine promethazine, which is used to relieve symptoms of allergy in several allergic conditions, including allergic contact dermatitis, allergic reactions to drugs, hives (urticaria), bites and stings; also allergic rhinitis caused by seasonal allergies like hayfever. Histamine is a chemical released from mast cells, (cells involved in allergies) as part of the body’s defence mechanism during an allergic reaction and binds to H1 receptors in small blood vessels causing them to leak, allowing white blood cells and blood proteins into the tissues. These infiltrating cells produce inflammatory chemicals (prostaglandins and leukotrienes) that cause tissue swelling and irritation, which are symptoms of an allergic reaction. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors and blocking the action of histamine without blocking its secretion. This action blocks histamine-mediated allergic reactions, relieving symptoms in the upper respiratory tract like nasal congestion, runny itchy nose and sneezing, and in the skin like redness, swelling and itching.

Treating motion sickness with Phenergan

Phenergan tablets 25mg contain promethazine, an antihistamine that is used to control the nausea and vomiting associated with motion sickness caused by all forms of travel including, air, sea train or car travel. The inner ear contains the vestibular apparatus, comprising the membranous labyrinth structures of the cochlea and semicircular canals, where motion or changes in the body’s position is detected and continual information about body position is transmitted to the brain. Motion causes the endolymph (fluid that fills the inner ear) to trigger electrical signals via special sensory cells sending nerve impulses via neurotransmitters (chemicals that allow nerve cells to communicate) along the auditory nerve to the brain to be interpreted. Motion sickness is caused by conflicting information being received by the brain from the eyes and the vestibular system; messages sent by the ear suggest motion, whereas the messages sent by the eye suggest that the body is still. The conflicting information received into the brain stimulates the area postrema or vomiting centre of the brain to induce the vomiting reflex. Promethazine in Phenergan tablets 25mg binds to histamine receptors on cells of the vestibular apparatus of the inner ear and is also thought to bind to histamine receptors on nerve cells in the brain and this blocks the transmission of nerve impulses from the inner ear to the vomiting center in the brain, which in turn prevents transmission of nerve signals from the brain to receptors in the stomach, so that the vomiting reflex is blocked. Phenergan tablets 25mg are also used to reduce nausea and vomiting due to several conditions including postoperative vomiting, irradiation sickness and drug-induced nausea.

Phenergan for sedation

Phenergan tablets 25mg contain promethazine, an antihistamine that has sedating properties. Promethazine in Phenergan tablets 25mg is an H1 receptor antagonist and works by binding to histamine receptors in various parts of the body including the brain. Some brain neurones (nerve cells) produce histamine and the action of histamine in the brain is involved in stress and anxiety reactions. Blocking these brain histamine receptors is thought to be responsible for causing sedation.

What are the side effects of Phenergan?

The most commonly reported side effects when taking Phenergan tablets 25mg include: dry mouth, gastro-intestinal disturbances (diarrhoea, constipation, nausea, vomiting or abdominal pain) loss of appetite, tiredness, sleepiness, restlessness, dizziness, blurred vision.

When should Phenergan not be used?

You should not use Phenergan tablets 25mg if you:

are allergic to promethazine or any ingredients in Phenergan
are allergic to sulphites, benzoates or phenothiazines
are pregnant or are breastfeeding
have had jaundice induced by other phenothiazine derivatives
are taking medicines that interact with Phenergan, including: monoamine oxidase inhibitors (MAOIs) (up to 14 days previously), tricyclic antidepressants, sedatives and hypnotics, opioid analgesics, barbiturates

Phenergan tablets 25mg should not be used for children under 2 years or for anyone in a coma.

What medications interact with Phenergan?

Several medications interact with Phenergan tablets 25mg to increase side effects and can cause a serious reaction and should either not be taken while you are taking Phenergan or only after discussion and instruction from your doctor: including: monoamine oxidase inhibitors (MAOIs) (up to 14 days previously, tricyclic antidepressants, sedatives and hypnotics, opioid analgesics, barbiturates.

How should Phenergan be taken?

You should take your Phenergan tablets 25mg swallowed whole with a glass of water. The dose you take and how often depends on what you are being treated for and your doctor’s recommendation. For allergy and sedation you should take your Phenergan tablets 25mg at night. For travel sickness you should take one tablet the night before travel and you can take another dose the next day, provided 6-8 hours has elapsed. For nausea and vomiting you should take your Phenergan tablets 25mg every 4 to 6 hours as recommended by your doctor. You should continue to take your Phenergan tablets 25mg for as long as your symptoms persist, or as recommended by your doctor but for no longer than 10 consecutive days.

How long should you take Phenergan?

You should continue to take your Phenergan tablets 25mg for as long as your symptoms persist, or as recommended by your doctor but for no longer than 10 consecutive days.

Missed dose of Phenergan

If you miss a dose of Phenergan tablets 25mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

How should Phenergan be stored?

You should store your Phenergan below 25°C in a cool dry place.

Muply (Mupirocin 2%) Ointment

Muply general information

What is Muply used for?

Muply ointment is a topical treatment for a variety of primary bacterial skin infections, including, impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root ; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also used to treat secondary infections that occur in damaged skin, for example due to eczema, psoriasis, atopic dermatitis, herpes (cold sores), epidermolysis bullosa (an inherited diseases characterised by blistering lesions on the skin and mucous membranes), icthyosis (genetic skin disorders that cause dry, fragile skin); also for treatment of infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites, as well as to prevent the development of infection and help wound healing.

How does Muply work?

Muply ointment contains mupirocin, an antibiotic that has very potent bactericidal activity, and is used as a topical treatment for a variety of primary skin infections; and secondary infections that occur in damaged skin and in skin lesions. Mupirocin in Muply ointment inhibits protein and RNA synthesis in susceptible bacteria, which include staphylococci, streptococci, and Haemophilus influenza. This action of mupirocin in Muply ointment blocks growth and replication of the susceptible bacteria, and prevents the spread of the infection.

What does Muply contain?

Muply ointment contains the active ingredient mupirocin 2%, a topical antibiotic used to treat variety of skin infections.

Treating skin infections with Muply

Muply ointment contains mupirocin, an antibiotic that is used as a topical treatment for a variety of skin infections. Skin infections that Muply ointment is used for include impetigo, a superficial skin infection most common in young children; folliculitis, infection of the hair root; furunculosis, also known as boils; ecthyma, a deep, ulcerating infection of the skin caused by streptococcus bacteria. Muply ointment is also effective against secondary infections that occur in damaged skin due to eczema, psoriasis, atopic dermatitis, herpes and genetic skin disorders that cause dry, fragile skin; as well as for infected traumatic lesions such as wounds, ulcers, minor burns, cuts, grazes and insect bites; and to prevent the development of infection and help wound healing. Mupirocin in Muply ointment inhibits the protein and RNA synthesis in susceptible bacteria, which blocks growth and replication of these bacteria and prevents the spread of the infection.

What are the side effects of Muply?

The most commonly reported side effects when taking Muply include itching, dryness, burning, redness, stinging, pain or swelling.

When should Muply not be used?

You should not use Muply ointment if you:

are allergic to mupirocin or any ingredients in Muply
have an eye or nose infection, as Muply ointment is suitable only for skin infections

How should Muply be used?

You should apply your Muply ointment to the affected area three times each day. Squeeze a small amount onto your finger tip and rub in gently; always wash your hands before and after applying the ointment and avoid contact with the eyes. Your doctor may recommend applying a gauze to the infected area over the ointment. You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days.

How long should you use Muply?

You should continue to apply your Muply ointment for as long as recommended by your doctor, usually for up to 10 days.

Missed dose of Muply

If you miss a dose of Muply ointment apply it as soon as you remember, unless it is time to apply the next dose, then skip the missed dose. Do not apply a double dose.

How should Muply be stored?

You should store your Muply ointment below 25°C in a cool dry place; do not freeze the ointment.

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